<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Ochirbat Dagvadorj</style></author><author><style face="normal" font="default" size="100%">Javkhlan Bold</style></author><author><style face="normal" font="default" size="100%">Tserendagva Dalkh</style></author><author><style face="normal" font="default" size="100%">Selenge Erdenechimeg</style></author><author><style face="normal" font="default" size="100%">Bold Sharav</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Re-examining Crude Drugs used in the Treatment of COVID-19 from Ancient Medical Books</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Ancient medical books</style></keyword><keyword><style  face="normal" font="default" size="100%">Common cold</style></keyword><keyword><style  face="normal" font="default" size="100%">COVID-19</style></keyword><keyword><style  face="normal" font="default" size="100%">Influenza</style></keyword><keyword><style  face="normal" font="default" size="100%">Mana-4</style></keyword><keyword><style  face="normal" font="default" size="100%">Norov-7</style></keyword><keyword><style  face="normal" font="default" size="100%">Traditional medicine</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2025</style></year><pub-dates><date><style  face="normal" font="default" size="100%">June 2025</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">17</style></volume><pages><style face="normal" font="default" size="100%">327-330</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Purpose:&lt;/strong&gt; Research ancient medical books to find the medicinal ingredients used in the two most widely used recipes for treating COVID-19. &lt;strong&gt;Research materials: &lt;/strong&gt;1. The following materials were used in the study. Including: Lamyn gegeen Luvsandanzanjantsan (1649-1704). “Man ngag bdud rtsi zegs ma.” Wooden printing block with Tibetan script. 2. Toin Jambaldorj (1792-1855). Gso byed bdud rtsi'i 'khrul med ngos 'dzin bzo rig me long du rnam par shar ba mdzes mtshar mig rgyan zhes bya ba bzhugs so. Wooden printing block with Tibetan script.&lt;strong&gt; Research Methods: &lt;/strong&gt;Methods of textual analysis for ancient books and checklist methods were used in the study. &lt;strong&gt;Conclusion:&lt;/strong&gt; The most effective and most widely used drugs for the treatment of COVID-19 were Mana-4 and Norov-7 decoctions. The source of these two decoctions is Lamyn gegeen Luvsandanzanjantsan’s (1649-1704) book “Man ngag bdud rtsi zegs ma”. This book was one of the main textbooks at the Medical School established in Mongolia in 1685. The traditional medicinal indications and usages of the 7 medicinal crude drugs included in the composition of Mana-4 and Norov-7 decoctions were studied in detail in Toin Jambaldorj’s book “Beautiful Marvelous Eye Ornament.” Apart from these 7 medicinal crude drugs, 6 medicinal crude drugs have the effect of treating influenza and influenza-like illnesses according to modern medical theory. Therefore, it has been established that Mana- 4 and Norov-7 decoctions have the effect of treating infectious febrile disorders accompanied by cold chills and shivering, preliminary stages of influenza, and open up bodily pores and induce sweat.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">327</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Ochirbat Dagvadorj&lt;sup&gt;1&lt;/sup&gt; , Javkhlan Bold&lt;sup&gt;1&lt;/sup&gt;, Tserendagva Dalkh&lt;sup&gt;1&lt;/sup&gt;, Selenge Erdenechimeg&lt;sup&gt;2&lt;/sup&gt;, Bold Sharav&lt;sup&gt;2,3&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Mongolian National University of Medical Sciences, Post Box 48/111, Ulaanbaatar city 14210, Mongolia&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Mongolian University of Pharmaceutical Sciences PO-37, Box-59, Ulaanbaatar 18080, Mongolia&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;“Ach” Medical University, Peace Avenue, Ulaanbaatar 18101&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Mfundisi Nhlapo</style></author><author><style face="normal" font="default" size="100%">Brian Ngobeni</style></author><author><style face="normal" font="default" size="100%">Idah Manduna</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">A Review: Medicinal Uses, Phytochemistry and Pharmacological Properties of Plants from the Hermannia Genus</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Bioactive compounds</style></keyword><keyword><style  face="normal" font="default" size="100%">drug development</style></keyword><keyword><style  face="normal" font="default" size="100%">Hermannia</style></keyword><keyword><style  face="normal" font="default" size="100%">Pharmacological activities</style></keyword><keyword><style  face="normal" font="default" size="100%">Phytochemistry</style></keyword><keyword><style  face="normal" font="default" size="100%">Secondary metabolites</style></keyword><keyword><style  face="normal" font="default" size="100%">Traditional medicine</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2025</style></year><pub-dates><date><style  face="normal" font="default" size="100%">June 2025</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">17</style></volume><pages><style face="normal" font="default" size="100%">384-393</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; Medicinal plants play a pivotal role in treating illnesses and modern medicines are still being derived from plants. Hermannia genus is a significant traditional herbal medicine. This review evaluates the medicinal uses, phytochemistry and pharmacological properties of plants from the genus Hermannia genus based on available research. &lt;strong&gt;Methods:&lt;/strong&gt; Studies accessed from online research databases were systematically selected and analysed to construct a comprehensive review of the medicinal uses, phytochemistry and pharmacological properties of plants from the genus. &lt;strong&gt;Results: &lt;/strong&gt;Hermannia species are used in traditional medicine to treat or manage; respiratory conditions, gastrointestinal issues, skin conditions, sexually transmitted infections, and diabetes. Scientific findings also discovered promising pharmacological activities within members of the genus such as antimicrobial, anti-inflammatory, antioxidant, antidiabetic and anticancer activities. To date, over 30 types of secondary metabolites have been identified from the genus, including the 2 pure compounds that were isolated and tested for pharmacological activities. Further research must prioritize other unexplored species of the genus and efficacy and mechanism of action studies on isolated compounds. &lt;strong&gt;Conclusion: &lt;/strong&gt;The genus Hermannia is important in the treatment of diseases of high public health concern. The pharmacological studies and presence of secondary metabolites and bioactive compounds further validates the traditional uses of the genus. Therefore, the findings suggest that the genus has species that may serve as candidates for novel drug discovery for the treatment of various illnesses. Efficacy and mechanism of action studies still need to be conducted on isolated compounds and other unexplored species of the genus.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Review Article</style></work-type><section><style face="normal" font="default" size="100%">384</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Mfundisi Nhlapo&lt;sup&gt;1&lt;/sup&gt;, Brian Ngobeni&lt;sup&gt;2*&lt;/sup&gt;, Idah Manduna&lt;sup&gt;3&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Health Sciences, Central University of Technology, Free State, SOUTH AFRICA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Clinical Sciences, Central University of Technology, Free State SOUTH AFRICA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Centre for Applied Food Sustainability and Biotechnology, Faculty of Health and Environmental Sciences, Central University of Technology, Free State, SOUTH AFRICA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Durga Prasad Kondeti</style></author><author><style face="normal" font="default" size="100%">T. Sundarrajan</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">A Review on Chemical Profile and Pharmacological Properties of Marine Sponge Tectitethya Crypta</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Anticancer drugs</style></keyword><keyword><style  face="normal" font="default" size="100%">Antiviral drugs</style></keyword><keyword><style  face="normal" font="default" size="100%">Bioactive compounds</style></keyword><keyword><style  face="normal" font="default" size="100%">Marine sponges</style></keyword><keyword><style  face="normal" font="default" size="100%">pharmacological properties</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2025</style></year><pub-dates><date><style  face="normal" font="default" size="100%">September 2025</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">17</style></volume><pages><style face="normal" font="default" size="100%">608-619</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;Marine sponges have gained recognition as a valuable resource due to their significant pharmacological properties. The investigation of substances produced by sponges has been extensively researched to identify their pharmacological properties. Marine sponges, which are part of the phylum Porifera, are thought to be the main source of marine natural products. Sponges are multicellular organisms that have a number of pores and channels for exchanging water; the secondary metabolites they create are in turn influenced by their specific environmental circumstances. Natural products such as lipids, terpenoids, peptides, alkaloids, and steroids are abundant in the marine sponge genus Tectitethya crypta. These compounds have unique chemical structures and have shown promising biological activities, making them ideal candidates for the development of novel drugs to treat various ailments. Tectitethya crypta is a sessile filter-feeder that produces a variety of bioactive compounds, including nucleosides and other secondary metabolites. This article reviews the biology and chemistry of Tectitethya crypta and serves as an introduction to the organism. We discuss the taxonomic classification, morphology, and microenvironment of the sponge, as well as the chemical structures and biological activities of its bioactive compounds. Tectitethya crypta was the source for the development of vidarabine, ara-C, and gemcitabine, which are used to treat viruses and cancer, respectively. We discussed about how these molecules may be used to treat parasitic and infectious disorders.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">608</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Durga Prasad Kondeti&lt;sup&gt;1&lt;/sup&gt;, T. Sundarrajan&lt;sup&gt;1*&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmaceutical Chemistry, SRM College of Pharmacy, SRM Institute of Science and Technology, Kattankulathur, Tamil Nadu, INDIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Dijeng Euginiah Rampana</style></author><author><style face="normal" font="default" size="100%">Pakiso Moses Makhoahle</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">A Review: Searsia genus and Its Potential Anti-Cancer Properties</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Anti-inflammatory</style></keyword><keyword><style  face="normal" font="default" size="100%">Anticancer</style></keyword><keyword><style  face="normal" font="default" size="100%">Antioxidant</style></keyword><keyword><style  face="normal" font="default" size="100%">Phytochemistry</style></keyword><keyword><style  face="normal" font="default" size="100%">Searsia genus</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2025</style></year><pub-dates><date><style  face="normal" font="default" size="100%">January 2025</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">17</style></volume><pages><style face="normal" font="default" size="100%">117-120</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;The &lt;em&gt;Searsia genus&lt;/em&gt;, belonging to the &lt;em&gt;Anacardiaceae&lt;/em&gt; family, comprises small trees and evergreen shrubs primarily found in Southern Africa, with some species extending to East Africa and the Mediterranean. While these species are well-known for their ecological roles in stabilizing soils and providing habitat for wildlife, they also possess significant medicinal value, particularly in traditional African medicine. Searsia plants are rich in bioactive compounds such as flavonoids, phenolic acids, and tannins, which exhibit potent anti-inflammatory, antibacterial, antioxidant, and anticancer properties. This has drawn scientific interest, especially regarding their potential in cancer treatment. Notably, &lt;em&gt;Searsia chirindensis&lt;/em&gt; and other species have demonstrated cytotoxic effects against various cancer cell lines, attributed to compounds like gallic acid and other polyphenolics. This review delves into the phytochemical profiles of selected &lt;em&gt;Searsia species&lt;/em&gt;, exploring their medicinal properties with a particular focus on their anticancer activities. The anti-inflammatory properties of these plants, coupled with their antioxidant activities, suggest a promising role in cancer prevention and treatment, although further research is necessary to confirm these benefits in clinical settings.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Review Article</style></work-type><section><style face="normal" font="default" size="100%">117</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Dijeng Euginiah Rampana*, Pakiso Moses Makhoahle&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;Department of Health Sciences, Faculty of Health Sciences, Central University of Technology, Bloemfontein, SOUTH AFRICA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Prajna R H</style></author><author><style face="normal" font="default" size="100%">Shivananda Nayak</style></author><author><style face="normal" font="default" size="100%">Priya V</style></author><author><style face="normal" font="default" size="100%">Shruthi Rai P</style></author><author><style face="normal" font="default" size="100%">Shivaraja shankara Y M</style></author><author><style face="normal" font="default" size="100%">Prashanthkumar Goudappala</style></author><author><style face="normal" font="default" size="100%">Dinesh PV</style></author><author><style face="normal" font="default" size="100%">Namratha KG</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">The role of TNF-Alpha, IL-6, Adiponectin, and Leptin in Inflammation and Metabolic Dysregulation in Type 2 Diabetes Mellitus</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Adiponectin</style></keyword><keyword><style  face="normal" font="default" size="100%">IL-6</style></keyword><keyword><style  face="normal" font="default" size="100%">Inflammation</style></keyword><keyword><style  face="normal" font="default" size="100%">Leptin</style></keyword><keyword><style  face="normal" font="default" size="100%">Metabolic Dysregulation</style></keyword><keyword><style  face="normal" font="default" size="100%">TNF-Alpha</style></keyword><keyword><style  face="normal" font="default" size="100%">Type 2 diabetes mellitus</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2025</style></year><pub-dates><date><style  face="normal" font="default" size="100%">December 2025</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">17</style></volume><pages><style face="normal" font="default" size="100%">699-702</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background: &lt;/strong&gt;Type 2 Diabetes Mellitus (T2DM) is characterized by chronic inflammation and metabolic dysregulation. The present study investigates the role of inflammatory markers, including TNF-alpha and IL-6, and metabolic hormones such as adiponectin and leptin, in individuals with T2DM. &lt;strong&gt;Methods:&lt;/strong&gt; A total of 147 participants diagnosed with T2DM were included in the study. Clinical and biochemical parameters, including fasting blood sugar (FBS), glycated hemoglobin (HbA1C), adiponectin, leptin, TNF-alpha, and IL-6, were measured. Descriptive statistics and correlation analysis were performed to determine associations between inflammatory markers and metabolic dysregulation.&lt;strong&gt; Results: &lt;/strong&gt;The mean age of participants was &lt;strong&gt;42.63 ± 6.38 &lt;/strong&gt;years, and the average BMI was &lt;strong&gt;28.38 ± 2.25 kg/m²&lt;/strong&gt;. FBS and HbA1C levels were &lt;strong&gt;175.72 ± 61.61 mg/dL&lt;/strong&gt; and &lt;strong&gt;7.26 ± 0.94%,&lt;/strong&gt; respectively. The mean adiponectin and leptin levels were &lt;strong&gt;4.71 ± 1.75 μg/mL&lt;/strong&gt; and &lt;strong&gt;20.58 ± 5.19 ng/mL&lt;/strong&gt;, respectively. TNF-alpha and IL-6 levels averaged &lt;strong&gt;132.00 ± 9.45 pg/mL&lt;/strong&gt; and &lt;strong&gt;33.52 ± 14.55 pg/mL&lt;/strong&gt;, respectively. Correlation analysis indicated an inverse relationship between adiponectin and BMI, while leptin was positively correlated with BMI and insulin levels. Elevated TNFalpha and IL-6 levels were associated with increased HbA1C and fasting blood glucose. &lt;strong&gt;Conclusion: &lt;/strong&gt;This study highlights the significant role of inflammatory markers in metabolic dysregulation among T2DM patients. Elevated TNF-alpha and IL-6 levels reinforce the link between chronic inflammation and impaired glucose metabolism. These findings underscore the need for anti-inflammatory strategies in diabetes management.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">699</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Prajna R H&lt;sup&gt;1,2&lt;/sup&gt;, Shivananda Nayak&lt;sup&gt;3&lt;/sup&gt;, Priya V&lt;sup&gt;4*&lt;/sup&gt;, Shruthi Rai P&lt;sup&gt;5&lt;/sup&gt;, Shivaraja shankara Y M&lt;sup&gt;6&lt;/sup&gt;, Prashanthkumar Goudappala&lt;sup&gt;7&lt;/sup&gt;, Dinesh PV&lt;sup&gt;8&lt;/sup&gt;, Namratha KG&lt;sup&gt;9&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Research scholar, SaveethaResearch Center, Saveetha Institute of Medical and Technical Sciences(SIMATS), Chennai, INDIA,600077&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Assistant Professor, Department of Biochemistry, KVG Medical College and Hospital, Sullia, INDIA, 574327&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Professor, Department of Biochemistry, Subbaiah Institute of Medical Science, Shivamogga, INDIA,577222&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Professor, Center of Molecular Medicine and Diagnostics (COMManD), Department of Biochemistry, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University Chennai, INDIA,600077&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;5&lt;/sup&gt;Professor, Department of Biochemistry, KVG Medical College and Hospital, Sullia, INDIA, 574327&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;6&lt;/sup&gt;Professor, Department of Biochemistry, KVG Medical College and Hospital, Sullia, INDIA, 574327&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;7&lt;/sup&gt;Associate Professor, Department of Biochemistry, Sri Siddhartha Medical College, Sri Siddhartha Academy of Higher Education, Tumkur, INDIA ,572107&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;8&lt;/sup&gt;Professor, Department of Community medicine, KVG Medical College and Hospital, Sullia, INDIA, 574327&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;9&lt;/sup&gt;Professor, Department of Microbiology, KVG Medical College and Hospital,Sullia , INDIA, 574327.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Junjungan Kristianto Manurung</style></author><author><style face="normal" font="default" size="100%">Prananda Surya Airlangga</style></author><author><style face="normal" font="default" size="100%">Hamzah Hamzah</style></author><author><style face="normal" font="default" size="100%">Prihatma Kriswidyatomo</style></author><author><style face="normal" font="default" size="100%">Anggraini Dwi Sensusiati</style></author><author><style face="normal" font="default" size="100%">Budi Utomo</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">The Relationship Between Blood Levels of Ubiquitin Carboxyterminal Hydrolase L1 (UCH-L1) Protein and the Severity of Traumatic Brain Injury Based on the Glasgow Coma Scale and Rotterdam CT Score</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Glasgow Coma Scale</style></keyword><keyword><style  face="normal" font="default" size="100%">Rotterdam CT score</style></keyword><keyword><style  face="normal" font="default" size="100%">Traumatic Brain Injury</style></keyword><keyword><style  face="normal" font="default" size="100%">UCH-L1</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2024</style></year><pub-dates><date><style  face="normal" font="default" size="100%">June 2024</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">16</style></volume><pages><style face="normal" font="default" size="100%">695-699</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Objective:&lt;/strong&gt; Traumatic brain injury (TBI) is a leading cause of disability and death worldwide, with an estimated 64-74 million cases annually. The current gold standard for diagnosis is a computed tomography (CT) scan, which has limitations such as access, cost, and radiation risk. Therefore, a simple, accessible, and safe diagnostic modality is needed, one of which is biomarker examination. This study aims to establish the relationship between blood levels of the biomarker ubiquitin carboxy-terminal hydrolase-L1 (UCH-L1) and the severity of TBI based on the Glasgow Coma Scale (GCS) and Rotterdam CT score. &lt;strong&gt;Material and Methods: &lt;/strong&gt;This observational analytic study with a cross-sectional design involved 41 samples aged 18-50 years who presented to the Emergency Department of Dr. Soetomo General Hospital, Surabaya, within 3-24 hours of the incident. UCH-L1 levels were measured from blood samples using the ELISA method, and the data on UCH-L1, GCS, and Rotterdam CT scores were analyzed with SPSS 29. &lt;strong&gt;Results:&lt;/strong&gt; The mean UCH-L1 level was 0.522 ± 0.592, with a cutoff value of &amp;gt; 0.2057, indicating moderate to severe TBI if UCH-L1 levels exceeded 0.2057. Spearman's test and correlation coefficient analysis showed a strong relationship between UCH-L1 levels and Rotterdam CT score (p &amp;lt; 0.05), as well as between UCH-L1 levels and TBI severity based on GCS (p &amp;lt; 0.05). The cutoff value for Rotterdam CT score was &amp;gt; 2, indicating moderate to severe TBI if the score exceeded 2. &lt;strong&gt;Conclusion:&lt;/strong&gt; Serum UCH-L1 levels are significantly associated with the severity of TBI based on GCS and Rotterdam CT score.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">695</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Junjungan Kristianto Manurung&lt;sup&gt;1&lt;/sup&gt;, Prananda Surya Airlangga&lt;sup&gt;1&lt;/sup&gt;*, Hamzah Hamzah&lt;sup&gt;1&lt;/sup&gt;, Prihatma Kriswidyatomo&lt;sup&gt;1&lt;/sup&gt;, Anggraini Dwi Sensusiati&lt;sup&gt;2&lt;/sup&gt;, Budi Utomo&lt;sup&gt;3&lt;/sup&gt;&amp;nbsp;&lt;/strong&gt;&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Anesthesiology and Intensive Care, Faculty of Medicine, Universitas Airlangga – Dr. Soetomo General Academic Hospital, Surabaya, INDONESIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Radiology, Faculty of Medicine, Universitas Airlangga – Airlangga University Hospital, Surabaya, INDONESIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;3&lt;/sup&gt;Departement of Public Health &amp;amp; Preventive Medicine, Faculty of Medicine, Universitas Airlangga – Dr. Soetomo General Academic Hospital, Surabaya, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Rian Nofiansyah</style></author><author><style face="normal" font="default" size="100%">Kohar Hari Santoso</style></author><author><style face="normal" font="default" size="100%">Prananda Surya Airlangga</style></author><author><style face="normal" font="default" size="100%">Prihatma Kriswidyatomo</style></author><author><style face="normal" font="default" size="100%">Hamzah</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Relationship Between Cerebrospinal Fluid S100B Levels with Glasgow Coma Scale and Rotterdam CT Score in Traumatic Brain Injury Patients</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Glasgow Coma Scale</style></keyword><keyword><style  face="normal" font="default" size="100%">Rotterdam CT score.</style></keyword><keyword><style  face="normal" font="default" size="100%">S100B</style></keyword><keyword><style  face="normal" font="default" size="100%">Traumatic Brain Injury</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2024</style></year><pub-dates><date><style  face="normal" font="default" size="100%">June 2024</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">16</style></volume><pages><style face="normal" font="default" size="100%">503-508</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;&lt;!-- x-tinymce/html --&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; Traumatic brain injury (TBI) stands as one of the foremost reasons for mortality and incapacitation in young adults on a global scale, accounting for nearly half of all injury-related deaths. The severity of TBI can be assessed using various biomarkers, with the SI00B protein being one of them. While many studies have explored the correlation between serum protein levels and various aspects such as neuroimaging findings, clinical scores, and neuropsychological evaluations, there is a notable lack of research examining the correlation with cerebrospinal fluid (CSF) levels. &lt;strong&gt;Methods: &lt;/strong&gt;The research design of this study was prospective and observational, employing analytic methods for analysis. Fifteen TBI patients who met the inclusion and exclusion criteria and were fitted with ICP monitors comprised the study sample. GCS data used is post-resuscitation GCS. Data on SIOOB protein levels were taken from the examination of CSF samples taken when the ICP monitor was installed. Rotterdam CT score variables was taken from the last CT scan performed before the patient was fitted with an ICP monitor. The statistical analysis was conducted utilizing the SPSS version 26 software. &lt;strong&gt;Results: &lt;/strong&gt;Demographic characteristics for this study tended to be more male (73.3%), with ages ranging from 18 to 65 years, and a mean age of 34.60 ± 16.22 years. The majority of injury mechanisms were traffic accidents (80%), and the most common lesion type was ICH. The mean CSF S 100B value of the 15 samples was 2753.689 pg/ ml. The results of the relationship test between S 100B CSF and GCS using the Spearman test obtained a p-value of less than 0.05, indicating a meaningful correlation between S 100B CSF and GCS, with a correlation coefficient or r value of -0.684. The results of the SIOOB CSF relationship test with Rotterdam CT Score obtained a p-value &amp;lt;0.05, with a correlation coefficient or r value of 0.827. &lt;strong&gt;Conclusion: &lt;/strong&gt;Increased levels of S100B in cerebrospinal fluid are associated with decreased GCS and increased Rotterdam CT score in traumatic brain injury patients.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">503</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Rian Nofiansyah&lt;sup&gt;1&lt;/sup&gt;*, Kohar Hari Santoso&lt;sup&gt;2&lt;/sup&gt;, Prananda Surya Airlangga&lt;sup&gt;2&lt;/sup&gt;, Prihatma Kriswidyatomo&lt;sup&gt;2&lt;/sup&gt;, Hamzah&lt;sup&gt;2&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;1&lt;/sup&gt;Clinical Medicine Study Program, Master’s Degree, Faculty of Medicine, Universitas Airlangga – Dr. Soetomo General Academic Hospital, Surabaya, INDONESIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Anesthesiology and Reanimation, Faculty of Medicine, Universitas Airlangga – Dr. Soetomo General Academic Hospital, Surabaya, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Ika Bella Rezqi Jaya</style></author><author><style face="normal" font="default" size="100%">Muhammad Yusran Amir</style></author><author><style face="normal" font="default" size="100%">Darmawansyah</style></author><author><style face="normal" font="default" size="100%">Sukri Palutturi</style></author><author><style face="normal" font="default" size="100%">Nurhaedar Jafar</style></author><author><style face="normal" font="default" size="100%">Muhammad Syafar</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">The Relationship of Marketing Mix with Patients' Decisions to Choose Health Services in Outpatient and Inpatient Installations at Sandi Karsa Hospital, Makassar</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Patient Decision</style></keyword><keyword><style  face="normal" font="default" size="100%">Performance</style></keyword><keyword><style  face="normal" font="default" size="100%">Physical Evidence</style></keyword><keyword><style  face="normal" font="default" size="100%">Price</style></keyword><keyword><style  face="normal" font="default" size="100%">Process</style></keyword><keyword><style  face="normal" font="default" size="100%">Product</style></keyword><keyword><style  face="normal" font="default" size="100%">Promotion</style></keyword><keyword><style  face="normal" font="default" size="100%">Staff</style></keyword><keyword><style  face="normal" font="default" size="100%">Strength</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2024</style></year><pub-dates><date><style  face="normal" font="default" size="100%">June 2024</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">16</style></volume><pages><style face="normal" font="default" size="100%">630-637</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;The marketing mix is a core business that is very closely related to the targeted patients, so that hospital efforts are specifically closely related to patient behavior in utilizing services. The aim of this research is to determine the relationship between the marketing mix and the patient's decision to choose health services in outpatient and inpatient installations at Sandi Karsa Hospital, Makassar. The type of research used is quantitative research with a cross sectional study design. The population in this study was 97 outpatients and 76 inpatients. Sample determination was carried out using the accidental sampling method. Data analysis used univariate, bivariate with chi square test and multivariate with multiple logistic regression test. The results showed that in outpatient installations, there was a relationship between product (p=0.003), staff (p=0.009), physical evidence (p=0.001), process (p=0.000), and performance (p=0.000), there was no relationship between price (p=1,000), promotion (p=0.554), place (p=1,000), and strength (p=1,000) with the patient's decision to choose health services at Sandi Karsa Hospital. Meanwhile, in inpatient installations there is a relationship between product (p=0.005), place (p=0.017), staff (p=0.000), process (p=0.002) and physical evidence (p=0.006), there is no price relationship (p= 0.674), promotion (p=1.000), performance (p=1.000), and strength (p=0.358) with the patient's decision to choose health services at Sandi Karsa Hospital Makassar.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">630</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Ika Bella Rezqi Jaya&lt;sup&gt;1&lt;/sup&gt;*, Muhammad Yusran Amir&lt;sup&gt;2&lt;/sup&gt;, Darmawansyah&lt;sup&gt;2&lt;/sup&gt;, Sukri Palutturi&lt;sup&gt;2&lt;/sup&gt;, Nurhaedar Jafar&lt;sup&gt;3&lt;/sup&gt;, Muhammad Syafar&lt;sup&gt;4&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Masters Student of Health Administration and Policy, Faculty of Public Health, Hasanuddin University, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Health Administration and Policy, Faculty of Public Health, Hasanuddin University, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Nutritional Sciences, Faculty of Public Health, Hasanuddin University, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Department of Health Promotion and Behavioral Sciences, Faculty of Public Health, Hasanuddin University, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Patnaree Wongmanit</style></author><author><style face="normal" font="default" size="100%">Kusuma Sriyakul</style></author><author><style face="normal" font="default" size="100%">Parunkul Tungsukruthai</style></author><author><style face="normal" font="default" size="100%">Ouppatham Supasyndh</style></author><author><style face="normal" font="default" size="100%">Pratya Phetkate</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Renal Resistive Index and Estimated Glomerular Filtration Rate in Nondiabetic Chronic Kidney Disease Stage 3: A Cross-Sectional Analytical Study</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2024</style></year><pub-dates><date><style  face="normal" font="default" size="100%">June 2024</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">16</style></volume><pages><style face="normal" font="default" size="100%">538-544</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; Renal resistive index (RRI) and estimated glomerular filtration rate (eGFR) are predictive markers for chronic kidney disease (CKD) progression. &lt;strong&gt;Aim:&lt;/strong&gt; To evaluate RRI value, eGFRcr-cys and renal biomarker in nondiabetic patients with CKD stage 3 in Bangkok, Thailand. &lt;strong&gt;Methods:&lt;/strong&gt; A cross-sectional analytical analysis was conducted involving nondiabetic patients with CKD stage 3, aged 35-85 years. Ultrasound was used to assess the RRI of arteries in both kidneys. Patients underwent assessments of serum and urine 24-hour. &lt;strong&gt;Results:&lt;/strong&gt; Among the 61 participants (67.2% male; mean age 69.03 ± 12.59 years), the mean eGFRcr-cys was 41.63 ± 8.64 mL/min/1.73 m², and the mean RRI was 0.65 ± 0.06. Patients were categorized into three RRI groups: low (&amp;lt;0.65, n=35), intermediate (0.65-0.70, n=14), and high (&amp;gt;0.70, n=12). The high RRI group showed a mean RRI of 0.73 ± 0.05 (p &amp;lt; 0.01). Among those with high RRI group were significant decreased right kidney size (p&amp;lt;0.05) and they had a lower BMI, averaging 22.49 ± 3.48. An increase in PP (59.66 ± 13.84, p=0.04) was also significant in this group. The correlations coefficient of RRI value showed a significant positive correlation with age (p&amp;lt;0.05) and significant negative with BMI (p&amp;lt;0.05). In addition, eGFRcr-cys displayed a significant negative correlation with UAGT and 24hUP (p&amp;lt;0.05) and a significant while eGFRcr-cys positive correlation with both kidney size and urine iNOS(p&amp;lt;0.01). &lt;strong&gt;Conclusion:&lt;/strong&gt; An increase in RRI is inversely linked to age, BMI, and PP. Lower eGFR is correlated with factors that cause CKD progression.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">538</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Patnaree Wongmanit&lt;sup&gt;1&lt;/sup&gt;, Kusuma Sriyakul&lt;sup&gt;1&lt;/sup&gt;, Parunkul Tungsukruthai&lt;sup&gt;1&lt;/sup&gt;, Ouppatham Supasyndh&lt;sup&gt;2&lt;/sup&gt;, Sucharat Tungsukruthai&lt;sup&gt;3&lt;/sup&gt;, Pratya Phetkate&lt;sup&gt;1&lt;/sup&gt;*&lt;/strong&gt;&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Integrative Medicine, Chulabhorn International College of Medicine, Thammasat University (Rangsit Campus), Pathum Thani, 12120, THAILAND.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;2&lt;/sup&gt;Faculty of Medicine, Kasetsart University, Ngamwongwan Rd, Chatuchak, Bangkok 10900, THAILAND.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;3&lt;/sup&gt;Division of Health and Applied Sciences, Faculty of Science, Prince of Songkla University, Hat Yai, Songkhla 90110, THAILAND.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Pakiso Moses Makhoahle</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">A Review: Understanding the Impact of Cancer During the Search of Safe and Affordable Medicinal Plants. A Need for In Vivo Investigation for the Safety Aspect of Asparagus Laricinus?</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Asparagus Laricinus</style></keyword><keyword><style  face="normal" font="default" size="100%">burden of cancer</style></keyword><keyword><style  face="normal" font="default" size="100%">Impact of cancer</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2024</style></year><pub-dates><date><style  face="normal" font="default" size="100%">August 2024</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">16</style></volume><pages><style face="normal" font="default" size="100%">975-981</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;&lt;!-- x-tinymce/html --&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;The understanding of the initiation, progression, and predictions about the burden of cancer are of importance during the scientific race for the discovery of much safer and cheap medicinal plants. The world population mostly relies on medicinal plants for the treatment of infections and diseases due to ongoing economic constraints and growing poverty. This review study seeks to establish the what the literature reported and the true extent to which &lt;em&gt;Asparagus laricinus&lt;/em&gt; is being studied for safe use. Studies indicate how cancer spreads and affects the different organs in the body. Most studies on medicinal plants are performed invitro with few concentrating to in vivo due to ethical requirements during the use of animal rats. Literature does not reveal any previous toxicological studiesafor &lt;em&gt;Asparagus laricinus&lt;/em&gt; per se in vivo, but several studies were performed on other medicinal plants used for the treatment of cancer. The safety aspects certain palnts were established for example &lt;em&gt;Moringa oleifera &lt;/em&gt;and &lt;em&gt;Lithocarpus dealbata&lt;/em&gt; were found to have no mortality or any visible signs of acute toxicity, while serum biochemistry tests did not reveal any noticeable changes in aspartate aminotransferase (AST), alanine aminotransferase (ALT), cholesterol (CHOL) and protein levels in animals. While in vivo showed high dose of toxicological studies on &lt;em&gt;Moringa oleifera&lt;/em&gt; have indicated to cause severe hepatotoxicity and organ damage. The acute lethality (LD50) test has been found to be relatively safe with subchronic toxicity studies, eliciting no significant difference in sperm quality, haematological and biochemical parameters in the treated rats, as compared to the controls . Both studies engaged the use of laboratory experimental animal models to evaluate the toxicology of plant extracts. With the growing interest in the use of &lt;em&gt;Asparagus laricinus &lt;/em&gt;in Botswana, South Africa, Lesotho and Swaziland for the treatment of infections and diseases, there is a need to correlate the published data with the in vivo data which is very scares current.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Review Article</style></work-type><section><style face="normal" font="default" size="100%">975</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Pakiso Moses Makhoahle&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;Faculty of Health and environmental Sciences, Central University of Technology-Free State, SOUTH AFRICA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Wibowo Artho Sutrisno</style></author><author><style face="normal" font="default" size="100%">Prananda Surya Airlangga</style></author><author><style face="normal" font="default" size="100%">Citrawati Dyah Kencono Wungu</style></author><author><style face="normal" font="default" size="100%">Prihatma Kriswidyatomo</style></author><author><style face="normal" font="default" size="100%">Hamzah</style></author><author><style face="normal" font="default" size="100%">Bambang Pujo Semedi</style></author><author><style face="normal" font="default" size="100%">Mahmudah</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">The Role of Neuron Specific Enolase, S100B, Glial Fibrillary Acidic Protein, and Myelin Basic Protein as Prognostic and Survival Values in Traumatic Brain Injury: Systematic Review and Meta-analysis</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Glial Fibriallary Acidic Protein</style></keyword><keyword><style  face="normal" font="default" size="100%">Myelin Basic Protein</style></keyword><keyword><style  face="normal" font="default" size="100%">Neuron Specific Enolase</style></keyword><keyword><style  face="normal" font="default" size="100%">Prognostic Value</style></keyword><keyword><style  face="normal" font="default" size="100%">S100B</style></keyword><keyword><style  face="normal" font="default" size="100%">Survival</style></keyword><keyword><style  face="normal" font="default" size="100%">Traumatic Brain Injury</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2024</style></year><pub-dates><date><style  face="normal" font="default" size="100%">April 2024</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">16</style></volume><pages><style face="normal" font="default" size="100%">478-484</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background: &lt;/strong&gt;The high number of accidents and traumatic brain injuries, especially in the productive age group, causes a lot of morbidity and mortality. A fast and accurate examination method is needed for the diagnosis and treatment of traumatic brain injury. Nerve damage biomarkers such as Neuron Specific Enolase, S100B, Glial Fibrillary Acidic Protein, and Myelin Basic Protein, have been used globally both for research and daily use to determine the severity of traumatic brain injury. &lt;strong&gt;Methods:&lt;/strong&gt; Searches and journal searches were carried out from Science Direct, Scopus, Springer Link, and PubMed, with the keywords &quot;Neuron Specific Enolase&quot;, &quot;S100B&quot;, &quot;Glial Fibrillary Acidic Protein&quot;, &quot;Myelin Basic Protein&quot;, and &quot;Traumatic Brain Injury ”. Screening was carried out using PRISMA 2021 to look for studies that met the criteria and were of sufficient study quality according to the Newcastle-Ottawa Scale. &lt;strong&gt;Results: &lt;/strong&gt;Twenty-three studies were collected and further grouped based on outcomes, both prognostic and survival outcomes. Neuron Specific Enolase, S100B, and Glial Fibrillary Acidic Protein values were higher in poor outcomes (all p values &amp;lt; 0.001) and poor survival (all p values &amp;lt; 0.001) in traumatic brain injury. Myelin Basic Protein was not significant in poor outcome (p = 0.35), but was higher in poor survival (p &amp;lt; 0.001) in traumatic brain injury. &lt;strong&gt;Conclusion:&lt;/strong&gt; Neuron Specific Enolase, S100B, and Glial Fibrillary Acidic Protein, can be used as markers for prognostic and survival value in traumatic brain injury. Myelin Basic Protein can be used as a marker for survival value in traumatic brain injury.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Review Article</style></work-type><section><style face="normal" font="default" size="100%">478</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Wibowo Artho Sutrisno&lt;sup&gt;1&lt;/sup&gt;, Prananda Surya Airlangga&lt;sup&gt;1*&lt;/sup&gt;, Citrawati Dyah Kencono Wungu&lt;sup&gt;2&lt;/sup&gt;, Prihatma Kriswidyatomo&lt;sup&gt;1&lt;/sup&gt;, Hamzah1, Bambang Pujo Semedi&lt;sup&gt;1&lt;/sup&gt;, Mahmudah&lt;sup&gt;3&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Anesthesiology and Reanimation, Faculty of Medicine, Airlangga University - Dr Soetomo General Academic Hospital, Surabaya, INDONESIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Physiology and Medical Biochemistry, Faculty of Medicine, Airlangga University, Surabaya, INDONESIA. 3Department of Community Health, Faculty of Community Health, Airlangga University, Surabaya, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Andi Lis Arming Gandini</style></author><author><style face="normal" font="default" size="100%">A. Ummu Salmah</style></author><author><style face="normal" font="default" size="100%">Stang</style></author><author><style face="normal" font="default" size="100%">A. Arsunan Arsin</style></author><author><style face="normal" font="default" size="100%">Anwar Mallongi</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">The Role of Parents in Monitoring the Growth and Development of Toddlers: A Systematic Review</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Development</style></keyword><keyword><style  face="normal" font="default" size="100%">Growth</style></keyword><keyword><style  face="normal" font="default" size="100%">Monitoring</style></keyword><keyword><style  face="normal" font="default" size="100%">Role of Parents</style></keyword><keyword><style  face="normal" font="default" size="100%">Toddlers</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2024</style></year><pub-dates><date><style  face="normal" font="default" size="100%">June 2024</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">16</style></volume><pages><style face="normal" font="default" size="100%">682-686</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; Toddler growth and development are important aspects that are interrelated. Growth is an increase in physical size and body structure while development is an increase in body structure and function in terms of movement, speech, language, socialization, and independence. The first five years of a child's life are a time of building learning, social, and emotional skills.1Children who receive stimulation provide good benefits for growth in body weight and mental development.2However, the growth and development of toddlers can experience disorders. The role of parents in monitoring the growth and development of toddlers is very important because it will influence the child's behavior as an adult. Applying parenting knowledge to children as early as possible is beneficial for the development of children's cognition and socio-emotional behavior.3Parenting is the overall interaction of parents with children that affect children's psychological and social.4Parenting groups are effective for increasing children's development, especially physical growth. The application of parenting techniques can be a method or way to help parents take better care of their children. &lt;strong&gt;Objective: &lt;/strong&gt;This study aimed to know the methods and implementers that can monitor the growth and development of toddlers. &lt;strong&gt;Methods: &lt;/strong&gt;This systematic review refers to the 2020 Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) guidelines. The databases used to search for articles are Pubmed and Google Scholar. The studies used were assessed using eight criteria from Strengthening the Reporting of Observational Studies in Epidemiology (STROBE). A total of 10 of 45,388 articles met the inclusion criteria for review. &lt;strong&gt;Results:&lt;/strong&gt; The programs for monitoring the growth and development of toddlers using an application is considered more effective for training family independence in preventing disease. Monitoring the growth and development of toddlers can be carried out by health workers, child development agents, researchers, and parents.&lt;strong&gt; Conclusion:&lt;/strong&gt; Parents can be effective implementers of monitoring because they are the closest people and the first for education place to their children. The use of the application is considered very effective for monitoring the growth and development of toddlers.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Review Article</style></work-type><section><style face="normal" font="default" size="100%">682</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Andi Lis Arming Gandini&lt;sup&gt;1,2&lt;/sup&gt;*, A. Ummu Salmah2, Stang&lt;sup&gt;2&lt;/sup&gt;, A. Arsunan Arsin&lt;sup&gt;2&lt;/sup&gt;, Anwar Mallongi&lt;sup&gt;2&lt;/sup&gt;&amp;nbsp;&lt;/strong&gt;&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;1&lt;/sup&gt;Faculty of Public Health, Universitas Hasanuddin, Makassar, INDONESIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;2&lt;/sup&gt;Nursing Department, Poltekkes Kemenkes of East Kalimantan, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Mardin M. Obied</style></author><author><style face="normal" font="default" size="100%">Entedhar R. Sarhat</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">The Role of Vitamin D-Binding Protein, and Procalcitonin in Patients with Arthritis on Vitamin D</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Arthritis</style></keyword><keyword><style  face="normal" font="default" size="100%">Procalcitonin</style></keyword><keyword><style  face="normal" font="default" size="100%">Vitamin D</style></keyword><keyword><style  face="normal" font="default" size="100%">Vitamin D-binding Protein</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2024</style></year><pub-dates><date><style  face="normal" font="default" size="100%">April 2024</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">16</style></volume><pages><style face="normal" font="default" size="100%">431-435</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; Arthritis is a term often used to mean any disorder that affects joints. Symptoms generally include joint pain and stiffness. Other symptoms may include redness, warmth, swelling, and decreased range of motion of the affected joints. In some types of arthritis, other organs are also affected. &lt;strong&gt;Aim:&lt;/strong&gt; This study aimed to identify the impact of vitamin D therapy on serum level of vitamin D-binding protein and procalcitonin in Patients with arthritis.&lt;strong&gt; Methods: &lt;/strong&gt;This cross-sectional study, was conducted in Kirkuk city between January 1st and March 1st, 2024. A total of 180 subjects were included, categorized into three groups: arthritis patients not receiving vitamin D (Group 1), arthritis patients receiving vitamin D for at least 2 months (Group 2), and a control group comprising 40 healthy subjects. Blood samples were collected from participants, processed, and stored for subsequent analysis. Various biomarkers, including vitamin D-binding protein and procalcitonin, were determined using ELISA kits. &lt;strong&gt;Results:&lt;/strong&gt; The study revealed a higher prevalence of females among arthritis patients (54.29%), with most affected individuals aged above 60 years. Urban residency was predominant among arthritis patients (75.71%). The majority of RA patients had been affected for 6-10 years (40%). Comparative analysis demonstrated significantly higher procalcitonin levels in RA patients without vitamin D supplementation (112.4±24.3 ng/ ml) compared to those with supplementation (48.33±10.73 ng/ml) and healthy controls (9.68±5.49 ng/ ml). Furthermore, vitamin D binding protein levels were significantly lower in arthritis patients without supplementation (1.26±0.12 ng/ml) compared to those with supplementation (0.75±0.15 ng/ml) and healthy controls (0.23±0.14 ng/ml).&lt;strong&gt; Conclusion: &lt;/strong&gt;These findings underscore the potential role of vitamin D supplementation in modulating inflammatory markers and enhancing vitamin D binding protein levels in arthritis patients, suggesting its therapeutic implications in disease management.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">431</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Mardin M. Obied&lt;sup&gt;1&lt;/sup&gt;, Entedhar R. Sarhat&lt;sup&gt;2,*&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;M1Kirkuk Health Directorate, Tikrit, IRAQ.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;College of Dentistry, Tikrit University, Tikrit, IRAQ.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Henu Hadiyantama</style></author><author><style face="normal" font="default" size="100%">Lukisiari Agustini</style></author><author><style face="normal" font="default" size="100%">Sutjipto</style></author><author><style face="normal" font="default" size="100%">Evelyn Komaratih</style></author><author><style face="normal" font="default" size="100%">Ismi Zuhria</style></author><author><style face="normal" font="default" size="100%">Pudji Lestari</style></author><author><style face="normal" font="default" size="100%">Ridholia</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">The Role of α-SMA, Type 1 Collagen, and Myofibroblasts in Cicatrizing Conjunctivitis by Alkali Chemical Trauma</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Cicatrizing conjunctivitis</style></keyword><keyword><style  face="normal" font="default" size="100%">Myofibroblasts</style></keyword><keyword><style  face="normal" font="default" size="100%">Type 1 collagen</style></keyword><keyword><style  face="normal" font="default" size="100%">α -SMA</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2024</style></year><pub-dates><date><style  face="normal" font="default" size="100%">May 2024</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">16</style></volume><pages><style face="normal" font="default" size="100%">591-596</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;Chemical trauma to the eye is a serious condition in the field of ophthalmology and a leading factor contributing to global blindness. Cicatrizing conjunctivitis (CC) is a term used to describe conditions marked by inflammation and the formation of scars on the conjunctiva. CC can have various causes, with one of them being chemical injury to the eye. The development of CC involves the participation of several cytokines and cells, such as α-SMA, Type 1 collagen, and Myofibroblasts. Myofibroblasts have the ability to contract through the utilization of diverse cytoskeletal proteins, which are commonly present in smooth muscle cells, including α-SMA. Actin filaments contribute to mechanically supporting cells, defining cell morphology, and facilitating cell mobility. Actin, in conjunction with myosin, participates in the muscle contraction process within muscle cells. Subsequently, type 1 collagen contributes to the healing of conjunctival wounds by providing a tensile force that aids in the closure of such wounds. As a significant constituent of the extracellular matrix, type 1 collagen plays a crucial role in maintaining the integrity of tissues.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">591</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Henu Hadiyantama&lt;sup&gt;1&lt;/sup&gt;, Lukisiari Agustini&lt;sup&gt;1*&lt;/sup&gt;, Sutjipto&lt;sup&gt;1&lt;/sup&gt;, Evelyn Komaratih&lt;sup&gt;1&lt;/sup&gt;, Ismi Zuhria&lt;sup&gt;1&lt;/sup&gt;, Pudji Lestari&lt;sup&gt;2&lt;/sup&gt;, Ridholia&lt;sup&gt;3&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Ophthalmology, Faculty of Medicine, Universitas Airlangga/Dr. Soetomo General Academic Hospital, Surabaya, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Public Health, Faculty of Medicine, Universitas Airlangga, Surabaya, INDONESIA. 3Department of Pathology Anatomy, Faculty of Medicine/Dr. Soetomo General Academic Hospital, Universitas Airlangga, Surabaya, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Aldila Pratiwi</style></author><author><style face="normal" font="default" size="100%">Martono Tri Utomo</style></author><author><style face="normal" font="default" size="100%">Risa Etika</style></author><author><style face="normal" font="default" size="100%">Kartika Darma Handayani</style></author><author><style face="normal" font="default" size="100%">Dina Angelika</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">The Relationship Between Enteral and Parenteral Nutrition on Body Weight, Incidence of NEC, Sepsis and Length of Care for Preterm Infant in Dr. Soetomo General Hospital Surabaya</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Enteral</style></keyword><keyword><style  face="normal" font="default" size="100%">Hospitalization.</style></keyword><keyword><style  face="normal" font="default" size="100%">Neonatal sepsis</style></keyword><keyword><style  face="normal" font="default" size="100%">Parenteral nutrition</style></keyword><keyword><style  face="normal" font="default" size="100%">Preterm infant</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2023</style></year><pub-dates><date><style  face="normal" font="default" size="100%">March 2023</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">15</style></volume><pages><style face="normal" font="default" size="100%">86-89</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;The incidence of preterm birth in Indonesia still accounts for the highest mortality rate. Failure to provide adequate nutrition will have an impact on growth failure, risk of infection and longer duration of care for preterm infant. This study aims to analyzing the relationship between enteral and parenteral nutrition on body weight, the incidence of NEC, the incidence of sepsis and the length of care at Dr. Soetomo Hospital Surabaya. A total 106 subjects were enrolled, 78 infants were LBW, 19 infants were VLBW. Gestational age between 32-&amp;lt;37 weeks as many as 96 subjects. 68 infants were female. A total of 49 patients (46.2%) received parenteral nutrition. There is a relationship between enteral nutrition and the incidence of sepsis (p= 0.03), parenteral nutrition and body weight (p= 0.005), parenteral nutrition and the incidence of sepsis (p= 0.001), and parenteral nutrition and the length of care for preterm infants (p= 0.001). There is a relationship between enteral nutrition with the incidence of sepsis and parenteral nutrition with body weight, incidence of sepsis and length of care in preterm infants.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Original Article </style></work-type><section><style face="normal" font="default" size="100%">86</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Aldila Pratiwi*, Martono Tri Utomo, Risa Etika, Kartika Darma Handayani, Dina Angelika&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;Department of Pediatrics, Faculty of Medicine, Universitas Airlangga, 60132, Surabaya, East Java/Dr. Soetomo General Hospital, 60286, Surabaya, East Java, INDONESIA&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Putri Ayuni Alayyannur</style></author><author><style face="normal" font="default" size="100%">Dani Nasirul Haqi</style></author><author><style face="normal" font="default" size="100%">Fatimatuz Zahroh</style></author><author><style face="normal" font="default" size="100%">Tazkia Azrielda Munib</style></author><author><style face="normal" font="default" size="100%">Moh. Malik Alhakim</style></author><author><style face="normal" font="default" size="100%">Diah Pramesthi Ningrum</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Relationship Between Individual Characteristics and the Risk of Exposure to Heat Stress in Indonesian Fishermen</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Age</style></keyword><keyword><style  face="normal" font="default" size="100%">Exercise Habits</style></keyword><keyword><style  face="normal" font="default" size="100%">Heat Stress</style></keyword><keyword><style  face="normal" font="default" size="100%">Water Drinking Consumption.</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2023</style></year><pub-dates><date><style  face="normal" font="default" size="100%">April 2023</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">15</style></volume><pages><style face="normal" font="default" size="100%">294-297</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; Fishermen who go to sea during the day are classified as informal sector jobs that have heavy activities and are at risk of becoming dehydrated because the work climate is in a hot environment due to exposure to sunlight.&lt;strong&gt; Objective: &lt;/strong&gt;The purpose of this study was to analyze the relationship between individual characteristics and the risk of heat stress exposure to fishermen in Surabaya Coastal Area. &lt;strong&gt;Materials and&lt;/strong&gt; &lt;strong&gt;Methods:&lt;/strong&gt; This research is a cross sectional study with a sample of 100 people using accidental sampling technique. The research was conducted in the Surabaya Coastal Area from February to June 2022. The variables of this study include age, exercise habits, water drinking consumption, and risk of heat stress. The relationship analysis test used Spearman correlation and chi square. Results: Based on cross tabulation, the age interval that experienced the most heat stress was 41-50 years of age, followed by 51-60 years of age group. Respondents who exercise more are at risk of heat stress than respondents who do not exercise. Workers who consume 1-2 liters of water per day are the group that has the highest risk of heat stress. &lt;strong&gt;Conclusion&lt;/strong&gt;: No one variable has a relationship with the risk of heat stress exposure to fishermen in Surabaya, but it is still important to increase the consumption of fisherman's water and doing exercise habits among fishermen in Surabaya.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Original Article </style></work-type><section><style face="normal" font="default" size="100%">294</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Putri Ayuni Alayyannur&lt;sup&gt;1,*&lt;/sup&gt;, Dani Nasirul Haqi&lt;sup&gt;1&lt;/sup&gt;, Fatimatuz Zahroh&lt;sup&gt;2&lt;/sup&gt;, Tazkia Azrielda Munib&lt;sup&gt;2&lt;/sup&gt;, Moh. Malik Alhakim&lt;sup&gt;3&lt;/sup&gt;, Diah Pramesthi Ningrum&lt;sup&gt;4&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Lecturer of Department of Occupational Safety and Health, Faculty of Public Health, Universitas Airlangga, Campus C, Mulyorejo, 60115, Surabaya, East Java, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Student of Bachelor Degree, Faculty of Public Health, Universitas Airlangga, Campus C, Mulyorejo, 60115, Surabaya, East Java, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Student of Bachelor Degree, Faculty of Dentistry, Universitas Airlangga, Campus A, Mayjen Prof. Dr. Moestopo Street No.47, 60132, Surabaya, East Java, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Employee of Health Office of Tapin District, Pembangunan Street No. 14, 71111, North Tapin, Tapin, South Kalimantan, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Malinda Meinapuri</style></author><author><style face="normal" font="default" size="100%">Arni Amir</style></author><author><style face="normal" font="default" size="100%">Eva Chundrayetti</style></author><author><style face="normal" font="default" size="100%">Efrida Efrida</style></author><author><style face="normal" font="default" size="100%">Susmiati Susmiati</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">The Relationship of the Gene Allele Apolipoprotein E with Height in Down Syndrome 21</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Apolipoprotein E</style></keyword><keyword><style  face="normal" font="default" size="100%">Down's Syndrome</style></keyword><keyword><style  face="normal" font="default" size="100%">Height.</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2023</style></year><pub-dates><date><style  face="normal" font="default" size="100%">October 2023</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">15</style></volume><pages><style face="normal" font="default" size="100%">897-900</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background: &lt;/strong&gt;Apolipoprotein E (APOE) is a form of polymorphic protein located on the long arm of chromosome 19 at position 13.2 (19q13.2), translated into three alleles of the gene, namely normal allele 3 and dysfunctional allele 2 and 4. Patients with Down's Syndrome Trisomy 21 may have different allele frequencies and combinations of APOE gene genotypes with controls, which can result in decreased cognitive function and inhibition of bone growth. This study aims to analyze the relationship of the Apolipoprotein E Gene Allele with the height of patients with Down Syndrome Trisomy 21. &lt;strong&gt;Methods:&lt;/strong&gt; This research is a cross sectional study with a comparative cross-sectional study design. &lt;strong&gt;Results&lt;/strong&gt;: The sample used was the result of DNA extraction of patients with Down's Syndrome Trisomy 21 as many as 33 samples and 33 controls stored in the Biomedical Laboratory, Faculty of Medicine, Andalas University, Padang, Indonesia. The next step is to examine the APOE gene polymorphisms using PCR and sequencing techniques. The results showed that there was a significant relationship between the APOE gene allele and height (p=0.009). &lt;strong&gt;Conclusion: &lt;/strong&gt;This study concluded that there was a significant relationship between the APOE gene allele and the height of patients with Down Syndrome Trisomy 21.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">897</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Malinda Meinapuri&lt;sup&gt;1,*&lt;/sup&gt;, Arni Amir&lt;sup&gt;2&lt;/sup&gt;, Eva Chundrayetti&lt;sup&gt;3&lt;/sup&gt;, Efrida Efrida&lt;sup&gt;4&lt;/sup&gt;, Susmiati Susmiati&lt;sup&gt;5&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Doctoral Student of Biomedical, Faculty of Medicine, Universitas Andalas, Padang, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Physiology, Faculty of Medicine, Universitas Andalas, Padang, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Pediatrics, Faculty of Medicine, Universitas Andalas, Padang, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Department of Clinical Pathology and Medical Laboratory, Faculty of Medicine, Universitas Andalas/RSUP dr. M. Djamil Padang, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;5&lt;/sup&gt;Department of Nursing, Faculty of Medicine, Universitas Andalas, Padang, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Maslichah Mafruchati</style></author><author><style face="normal" font="default" size="100%">Wan Irjani Wan Ismail</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">RETRACTED: Human Sperm for Basic Embryo Research And 3D Treatment of Patient-Representative Ovarian Cancer Cells</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">3D treatment</style></keyword><keyword><style  face="normal" font="default" size="100%">Basic embryo research</style></keyword><keyword><style  face="normal" font="default" size="100%">Human sperm</style></keyword><keyword><style  face="normal" font="default" size="100%">Ovarian cancer cells</style></keyword><keyword><style  face="normal" font="default" size="100%">Public health.</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2023</style></year><pub-dates><date><style  face="normal" font="default" size="100%">August 2023</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">15</style></volume><pages><style face="normal" font="default" size="100%">626-632</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;The article has been retracted based on the authors' request.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">626</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Maslichah Mafruchati&lt;sup&gt;1,*&lt;/sup&gt;, Wan Irjani Wan Ismail&lt;sup&gt;2&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Veterinary Anatomy, Faculty of Veterinary Medicine (60115), Universitas Airlangga, Mulyorejo, C Campus, Surabaya, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Science and Marine Environment, Universiti Malaysia Terengganu, Terengganu Malaysia, MALAYSIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Janany Manimaran</style></author><author><style face="normal" font="default" size="100%">Daruliza Kernain Mohd Azman</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">RETRACTED: The Effects of Andrographolide on Apoptosis in PC-3 Cell Line Via the Involvement of Caspases 3, 8 And 9</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Andrographolide</style></keyword><keyword><style  face="normal" font="default" size="100%">Anti-cancer</style></keyword><keyword><style  face="normal" font="default" size="100%">Apoptosis</style></keyword><keyword><style  face="normal" font="default" size="100%">Caspase.</style></keyword><keyword><style  face="normal" font="default" size="100%">PC-3 cell line</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2023</style></year><pub-dates><date><style  face="normal" font="default" size="100%">August 2023</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">15</style></volume><pages><style face="normal" font="default" size="100%">612-621</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;The Article has been Retracted based on the Authors' Request.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">612</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Janany Manimaran, Daruliza Kernain Mohd Azman*&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;Institute for Research in Molecular Medicine, University of Science Malaysia, 11800 Gelugor, Pulau Pinang, MALAYSIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Akingbolabo Daniel Ogunlakin</style></author><author><style face="normal" font="default" size="100%">Oyindamola Esther Awosola</style></author><author><style face="normal" font="default" size="100%">Gbenga Temidayo Ajayi</style></author><author><style face="normal" font="default" size="100%">Oluwafemi Adeleke Ojo</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Review on Phytochemistry of Medicinal Plants Documented for the Treatment of Low Sperm Count in Oluponna, Nigeria</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Ancestral medicinal plants records</style></keyword><keyword><style  face="normal" font="default" size="100%">Drug development.</style></keyword><keyword><style  face="normal" font="default" size="100%">Infertility</style></keyword><keyword><style  face="normal" font="default" size="100%">Low sperm count</style></keyword><keyword><style  face="normal" font="default" size="100%">Phytochemistry</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2023</style></year><pub-dates><date><style  face="normal" font="default" size="100%">April 2023</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">15</style></volume><pages><style face="normal" font="default" size="100%">439-446</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;According to the literature, approximately 32% of adult males in developing countries suffer from infertility, however, majority of them use herbal remedies with reported benefits such as improved sperm quality, sexual functions, libido and testosterone levels. Recently, the World Health Organization emphasized the importance of documenting active medicinal plants used in various continents. Therefore, this present review focused on the phytochemistry of medicinal plants reported for the treatment of low sperm count in Oluponna area of Osun state, documented in an ancestral local record. Thirteen medicinal plants were documented to be used for management of low sperm count among men in this community. The plants listed in the document belong to ten families and 12 genera. The most cited family in this record is Apocynaceae with three species of plants namely, &lt;em&gt;Alstonia boonei,&lt;/em&gt; &lt;em&gt;Laidolphia dulcis&lt;/em&gt;, and &lt;em&gt;Rauwolfia vomitoria&lt;/em&gt; respectively. Since this is the first review on the documentation of an ancestral knowledge and application of medicinal plants as means of passing the knowledge from a generation to another in Oluponna, additional toxicological and pharmacological studies are hereby recommended in order to provide scientific rationale for the long-term knowledge and use of these plants.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Review Article</style></work-type><section><style face="normal" font="default" size="100%">439</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Akingbolabo Daniel Ogunlakin&lt;sup&gt;1,2,*&lt;/sup&gt;, Oyindamola Esther Awosola&lt;sup&gt;3&lt;/sup&gt;, Gbenga Temidayo Ajayi&lt;sup&gt;4&lt;/sup&gt;, Oluwafemi Adeleke Ojo&lt;sup&gt;1,2&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Bowen University SDG 03 (Good Health and Wellbeing Research Cluster), NIGERIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Phytomedicine, Molecular Toxicology and Computational Biochemistry Research Group, Department of Biochemistry, Bowen University, Iwo, NIGERIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Next Era Health, Julius Kadir street, Ifako- Gbagada, Lagos, NIGERA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;College of Health Sciences, Bowen University, Iwo, NIGERA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Nurhayati Namira</style></author><author><style face="normal" font="default" size="100%">Anwar Daud</style></author><author><style face="normal" font="default" size="100%">Anwar Mallongi</style></author><author><style face="normal" font="default" size="100%">Hasnawati Amqam</style></author><author><style face="normal" font="default" size="100%">Atjo Wahyu</style></author><author><style face="normal" font="default" size="100%">Irwandy</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Risk Analysis of Microplastic Exposure Through Consumption of Anadara Granosa at Coastal Area</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Anadara Granosa.</style></keyword><keyword><style  face="normal" font="default" size="100%">Blood clams</style></keyword><keyword><style  face="normal" font="default" size="100%">Microplastic</style></keyword><keyword><style  face="normal" font="default" size="100%">Polystyrene</style></keyword><keyword><style  face="normal" font="default" size="100%">Risk analysis</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2023</style></year><pub-dates><date><style  face="normal" font="default" size="100%">August 2023</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">15</style></volume><pages><style face="normal" font="default" size="100%">558-562</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;Plastic waste is starting to threaten marine waters, especially microplastics. This micro-sized plastic can be consumed by marine biota. The accumulation of microplastics in the bodies of marine biota can threaten humans who consume them. The purpose of this study was to analyze the risk level of microplastic (polystyrene) exposure through the consumption of blood clams in the coastal area of Pao Village, Tarowang District, Jeneponto Regency. This type of research is a descriptive analysis with the Environmental Health Risk Analysis (EHRA) approach. The samples in this study were 30 respondents and 125 blood clams (&lt;em&gt;anadara granosa&lt;/em&gt;). Data were obtained by interview using a questionnaire, identifying MPs in shells in the laboratory, and identifying polymer types using FTIR-spectroscopy. The results showed that 68 MPs of microplastics were found in blood clams (&lt;em&gt;anadara granosa&lt;/em&gt;) samples. The dominant shapes were lines and blue. The types of polymers from the FTIR results are Polystyrene (PS), Low-density polyethylene (LDPE), Polyvinyl chloride (PVC), and Polyethylene (PE). The average non-carcinogenic daily intake (Intake) is 0.00012 mg/kg/day, the average risk level (RQ) is 0.0006, and the daily intake value is ≤0.2 (RfD Styrene), so it is said to be safe and the risk level value (RQ) ≤ 1, then categorized as the risk of exposure to MPs in humans through consumption of blood clams is still categorized as safe. The route of exposure to MPs in humans is not only through blood clams, so efforts to control the risk of exposure to MPs in humans are still needed.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Original Article </style></work-type><section><style face="normal" font="default" size="100%">558</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Nurhayati Namira, Anwar Daud*, Anwar Mallongi, Hasnawati Amqam, Atjo Wahyu, Irwandy&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;Faculty of Public Health, Hasanuddin University, Makassar City, South Sulawesi Indonesia, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Muh. Nur Amal Sali</style></author><author><style face="normal" font="default" size="100%">M. Furqan Naiem</style></author><author><style face="normal" font="default" size="100%">Masyitha Muis</style></author><author><style face="normal" font="default" size="100%">Syamsiar S. Russeng</style></author><author><style face="normal" font="default" size="100%">Atjo Wahyu</style></author><author><style face="normal" font="default" size="100%">Erniwati Ibrahim</style></author><author><style face="normal" font="default" size="100%">Anwar Mallongi</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">The Risk Analysis of Patient Transfer Practice Events to Safety of Nurses and Patients of the TNI AU Dodi Sardjoto Hospital</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Accident</style></keyword><keyword><style  face="normal" font="default" size="100%">Patient Transfer</style></keyword><keyword><style  face="normal" font="default" size="100%">Work safety</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2023</style></year><pub-dates><date><style  face="normal" font="default" size="100%">April 2023</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">15</style></volume><pages><style face="normal" font="default" size="100%">429-432</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;Work accidents can occur due to unsafe action and unsafe condition factors. This type of research is a combination of qualitative and quantitative research (mix method) with a phenomenological approach that aims to determine the risks of patient transfer practices to the safety of nurses and patients. This research was conducted at the TNI AU Dody Sardjoto Hospital with a total sample of 51 people, the sampling technique is simple random sampling. Then in-depth interviews will be conducted on key informants, ordinary informants, and additional informants. Quantitative data analysis using chi square test and multiple linear regression. The results of the study found that the history of disease (p = 0.010), physical activity (0.026), facilities and infrastructure (0.011), SOP (p = 0.000), and the environment (p = 0.000) influenced the safety of nurses. The results also showed that compliance with SOP (Standard Operating Procedure) was the most influential variable with B of 0.675. It is also known that the results of the path test have an indirect influence between nurse safety and patient safety is E2 = 0.887 or 88.7%. It is hoped that the results of this study can be a reference to reduce the risk of patient transfer practice events to the safety of nurses and patients.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">429</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Muh. Nur Amal Sali&lt;sup&gt;1,*&lt;/sup&gt;, M. Furqan Naiem&lt;sup&gt;2&lt;/sup&gt;, Masyitha Muis&lt;sup&gt;2&lt;/sup&gt;, Syamsiar S. Russeng&lt;sup&gt;2&lt;/sup&gt;, Atjo Wahyu&lt;sup&gt;2&lt;/sup&gt;, Erniwati Ibrahim&lt;sup&gt;3&lt;/sup&gt;, Anwar Mallongi&lt;sup&gt;3&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;1&lt;/sup&gt;Program Magister Kesehatan dan Keselamatan Kerja, Fakultas Kesehatan Masyarakat, Universitas Hasanuddin, INDONESIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;2&lt;/sup&gt;Departemen Kesehatan dan Keselamatan Kerja, Fakultas Kesehatan Masyarakat, Universitas Hasanuddin, INDONESIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;3&lt;/sup&gt;Departemen Kesehatan Lingkungan, Fakultas Kesehatan Masyarakat, Universitas Hasanuddin, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Nurul Iffa Safitri</style></author><author><style face="normal" font="default" size="100%">Nur Nasry Noor</style></author><author><style face="normal" font="default" size="100%">Wahiduddin</style></author><author><style face="normal" font="default" size="100%">Ridwan Amiruddin</style></author><author><style face="normal" font="default" size="100%">Nurhaedar Jafar</style></author><author><style face="normal" font="default" size="100%">Balqis</style></author><author><style face="normal" font="default" size="100%">Anwar Mallongi</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Risk Factors of Stunting in Children Aged 0-23 Months in Katumbangan Health Center, Indonesia</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Infant</style></keyword><keyword><style  face="normal" font="default" size="100%">Risk Factors.</style></keyword><keyword><style  face="normal" font="default" size="100%">Stunting</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2023</style></year><pub-dates><date><style  face="normal" font="default" size="100%">October 2023</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">15</style></volume><pages><style face="normal" font="default" size="100%">851-855</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;The results of Indonesian nutritional status study at the regency level in 2021 showed that Polewali Mandar Regency had the highest prevalence of stunting in West Sulawesi Province at 36% with the highest percentage of stunted toddlers being reported by Katumbangan Health Center (42.6%). This study aims to determine the most dominant risk factors for stunting in children aged 0-23 months. This study was conducted in the working area of Katumbangan Health Center with a case-control study. The number of samples was 236 infants (0-23 months) with a ratio of cases and controls of 1:1. This study used secondary data sourced form e-PPGBM application, then analyzed by odd ratio test and logistic regression on Stata. The results showed that CED in pregnancy (OR=3.142 with 95% CI, 1.122-10.072), LBW history (OR=5.963 with 95% CI, 1.251-56.216) and exclusive breastfeeding (OR=2.099 with 95% CI, 0.984-4.613). The dominant risk factor for stunting in children aged 0-23 months, namely LBW history (OR=5.092 with 95% CI, 1.08-23.94). It is recommended for mothers to put more attention to the fulfillment of nutrition during in order to reduce the risk of LBW and also to assure that children nutritionl intake are adequate to their needs during the golden period of growth, especially infants with LBW.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">851</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Nurul Iffa Safitri&lt;sup&gt;1,2*&lt;/sup&gt;, Nur Nasry Noor&lt;sup&gt;3&lt;/sup&gt;, Wahiduddin&lt;sup&gt;3&lt;/sup&gt;, Ridwan Amiruddin&lt;sup&gt;3&lt;/sup&gt;, Nurhaedar Jafar&lt;sup&gt;4&lt;/sup&gt;, Balqis&lt;sup&gt;5&lt;/sup&gt;, Anwar Mallongi&lt;sup&gt;6&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;FETP student, Public Health Study Program, Faculty of Public Health, Hasanuddin University, Makassar, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;West Sulawesi Provincial Health Office, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Epidemiology, Faculty of Public Health, Hasanuddin University, Makassar, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Nutrition Science Study Program, Faculty of Public Health, Hasanuddin University, Makassar, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;5&lt;/sup&gt;Department of Health Administration and Policy, Faculty of Public Health, Hasanuddin University, Makassar, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;6&lt;/sup&gt;Department of Environmental Health, Faculty of Public Health, Hasanuddin University, Makassar, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Asmaa Y Thanoon</style></author><author><style face="normal" font="default" size="100%">Faehaa Azher Al-Mashhadane</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Role of 1,25(OH)2D On Cytochromes CYP27A1 and CYP27B1 in  Periodontitis: A Clinical Study</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">CYP27</style></keyword><keyword><style  face="normal" font="default" size="100%">Cytochrome</style></keyword><keyword><style  face="normal" font="default" size="100%">Periodontitis</style></keyword><keyword><style  face="normal" font="default" size="100%">Vitamin D</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2023</style></year><pub-dates><date><style  face="normal" font="default" size="100%">December 2023</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">15</style></volume><pages><style face="normal" font="default" size="100%">1112-1115</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; Vitamins have a great impact on metabolis. &lt;strong&gt;Aims: &lt;/strong&gt;To determine the role of 1,25(OH)2D On Cytochromes CYP27A1 and CYP27B1 in Periodontitis. &lt;strong&gt;Material and Method:&lt;/strong&gt; The investigation was carried out on 45 participants of ages within the range of (30-45 years) who were attending the private dental clinics. Diagnosis of chronic periodontitis was established depending on dental history, clinical examinations (periodontal indices). All participants were examined by the same dentist. They were classified into three groups: Group 1 (control negative): (15) participants with normal serum vitamin D3 level and with pocket depth ≤3 mm, good oral health and normal periodontal tissues and no previous history of periodontal diseases. Group 2 (control positive): (15) participants with normal serum vitamin D3 level and periodontitis with pocket depth ≥5 mm, they received placebo medication orally, Group3(treatment): (15) participants with vitamin D3 deficiency (below 30 IU), and periodontitis with pocket depth ≥5 mm, they received oral Vitamin D3 fast acting liquid soft gel capsule 2000 IU /day for 3 months. 3 blood samples were taken from each participant at 0,45,90 days, for research examinations. CYP27A1, CYP27B1 serum levels was measured for each sample in three groups by ELISA kit. &lt;strong&gt;Result:&lt;/strong&gt; there was a highly significant reduction in CYP27A1 serum level in the treatment group at the ninety days of the study while there was no significant elevation CYP27B1 serum level in all groups during 45,90 days of the study. &lt;strong&gt;Conclusion:&lt;/strong&gt; The present study suggested that the 1,25(OH)2D has effects on serum levels of both Cytochromes CYP27A1 and CYP27B1 and this was associated with periodontitis.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">1112</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Asmaa Y Thanoon*, Faehaa Azher Al-Mashhadane&lt;/strong&gt;&lt;/p&gt;

&lt;p&gt;Department of Dental Basic Sciences, University of Mosul, Mosul, IRAQ.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Maylita Sari</style></author><author><style face="normal" font="default" size="100%">Kartika Misalina</style></author><author><style face="normal" font="default" size="100%">M. Yulianto Listiawan</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">The Role of Cyclooxigenase-2 Inhibitor in Basal Cell Carcinoma: A Literature Review</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Basal cell carcinoma.</style></keyword><keyword><style  face="normal" font="default" size="100%">Cancer</style></keyword><keyword><style  face="normal" font="default" size="100%">Chemoprevention</style></keyword><keyword><style  face="normal" font="default" size="100%">Cox-2 inhibitor</style></keyword><keyword><style  face="normal" font="default" size="100%">Cyclooxygenase</style></keyword><keyword><style  face="normal" font="default" size="100%">Skin malignancy</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2023</style></year><pub-dates><date><style  face="normal" font="default" size="100%">March 2023</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">15</style></volume><pages><style face="normal" font="default" size="100%">233-238</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;Basal cell carcinoma (BCC) is the most common skin malignancy worldwide. It has low mortality but can cause significant morbidity primarily due to local destruction. The incidence and associated cost are rising in recent years causing a burden in healthcare system. BCC incidence are continue to increase due to lack of effective chemopreventive option. Several risk factors are associated with the pathogenesis of BCC. One of the major risk factors of BCC is exposure to ultraviolet (UV) rays, hence the prevention strategy for this malignancy include avoidance of natural and artificial sources of UV radiation. However, these methods are still less than optimal in inhibiting the emergence of basal cell carcioma. In recent years, there is accumulating evidence that cyclooxygenase-2 (COX-2), may be involved in the pathogenesis of BCC. Several recent studies have shown that the use of cyclooxygenase-2 (COX-2) inhibitor drugs can prevent the development of nonmelanoma skin tumors including BCC. In this review, we described the potential of COX-2 inhibitors as chemoprevention for BCC.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Review Article</style></work-type><section><style face="normal" font="default" size="100%">233</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Maylita Sari, Kartika Misalina, M. Yulianto Listiawan*&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;Department of Dermatology and Venereology, Universitas Airlangga/ Dr. Soetomo General Academic Teaching Hospital, Surabaya, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Em Sutrisna</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">The Role of CYP3A4 and CYP2C8 Polymorphism on Amiodarone Responses: Review Article</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Amiodarone responses.</style></keyword><keyword><style  face="normal" font="default" size="100%">CYP2C8</style></keyword><keyword><style  face="normal" font="default" size="100%">CYP3A4</style></keyword><keyword><style  face="normal" font="default" size="100%">Polymorphism</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2023</style></year><pub-dates><date><style  face="normal" font="default" size="100%">June 2023</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">15</style></volume><pages><style face="normal" font="default" size="100%">467-470</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction&lt;/strong&gt;: Amiodarone is one of drug with narrow therapeutics index. This medicine was metabolized by CYP3A4 and CYP2C8. The changes in the activity of this enzymes by CYP3A4 and CYP2C8 polymorphism will affect the effect. The study aimed to determine the impact of CYP3A4 and CYP2C8 polymorphism on amiodarone responses.&lt;strong&gt; Method: &lt;/strong&gt;the study is review article with search article in PubMed with keywords: ‘amiodarone’ and ‘polymorphism of CYP3A4’ and ‘polymorphism of CYP2C8’. &lt;strong&gt;Results&lt;/strong&gt;: We collect 46 references to determine of impact polymorphism of CYP3A4 and CYP2C8 on amiodarone responses. &lt;strong&gt;Conclusion: &lt;/strong&gt;Individual with CYP3A4*22 (rs35599367, 15389C&amp;gt;T); CYP2C8*2 (A805T), CYP2C8*3 (G416A, A1196G), and CYP2C8*4 (C792G) and CYP2C8*4 polymorphism have lower activity of CYP3A4 and CYP2C8 enzymes and potentially cause adverse effect.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Review Article</style></work-type><section><style face="normal" font="default" size="100%">467</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Em sutrisna&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;Pharmacology laboratory of medical faculty of Universitas Muhammadiyah Surakarta, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Arti Gautam</style></author><author><style face="normal" font="default" size="100%">Lal Chand Pal</style></author><author><style face="normal" font="default" size="100%">Ch. V Rao</style></author><author><style face="normal" font="default" size="100%">Vikas Kumar</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">The Role of Indian Magical Herb Selaginella bryopteris L. (Selaginaceae) in Pharmacotherapeutic Perspective: An Overview</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Biflavonoid</style></keyword><keyword><style  face="normal" font="default" size="100%">S. bryopteris L.</style></keyword><keyword><style  face="normal" font="default" size="100%">Sanjeevni</style></keyword><keyword><style  face="normal" font="default" size="100%">Selaginaceae</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2023</style></year><pub-dates><date><style  face="normal" font="default" size="100%">March 2023</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">15</style></volume><pages><style face="normal" font="default" size="100%">14-20</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;This review involves the medicinal as well as therapeutic applications of Sanjeevni (&lt;em&gt;Selaginella bryopteris&lt;/em&gt; L.) in curtailing different types of acute and chronic maladies. The magical herb (&lt;em&gt;Selaginella bryopteris&lt;/em&gt;) is utilized for its resurrecting and medicinal properties in various regions of the world. &lt;em&gt;S. bryopteris&lt;/em&gt; based formulations have been widely used in folk medicine to treat spermatorrhoea, colitis, epilepsy, leucorrhoea, urinary tract infections, fever, venereal illnesses, constipation, beri-beri, cancer, and many other ailments. The medicinal and pharmacological effects of &lt;em&gt;S. bryopteris &lt;/em&gt;have been extensively studied in recent years, employing a variety of&lt;em&gt; in vivo&lt;/em&gt; and&lt;em&gt; in vitro&lt;/em&gt; models and clinical studies. Many biochemical and pharmacological studies on &lt;em&gt;Selaginella bryopteris&lt;/em&gt; have been conducted, and many of its traditional applications have been validated scientifically. Different biological activities are concerned with it, like anti-bacterial, growth-promoting, anti-protozoan, relief from heat stroke and the burning sensation during urination, anti-stress cell death, memory improvement, relief from stomach-aches, anti-hyperglycemic activity, and anti-depressant activity. S. bryopteris is undeniably one of the most significant plants owing to its enormous pharmacological and therapeutic potential. On the other hand, several information gaps found in this article might spur fresh academic and R&amp;amp;D efforts to produce S. bryopteris-based herbal medications and nutraceuticals.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Original Article </style></work-type><section><style face="normal" font="default" size="100%">14</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Arti Gautam&lt;sup&gt;1&lt;/sup&gt;, Lal Chand Pal&lt;sup&gt;2&lt;/sup&gt;, Ch. V Rao&lt;sup&gt;2&lt;/sup&gt;, Vikas Kumar&lt;sup&gt;1*&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmaceutical Sciences, Sam Higginbottom University of Agriculture, Technology &amp;amp; Sciences (SHUATS), Naini, Prayagraj, Uttar Pradesh, INDIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Pharmacology Division, National Botanical Research Institute (CSIR), Lucknow, Uttar Pradesh, INDIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Agus Purnomo</style></author><author><style face="normal" font="default" size="100%">Hartiningsih</style></author><author><style face="normal" font="default" size="100%">Setyo Budhi</style></author><author><style face="normal" font="default" size="100%">Dhirgo Adji</style></author><author><style face="normal" font="default" size="100%">Devita Anggraeni</style></author><author><style face="normal" font="default" size="100%">Dito Anggoro</style></author><author><style face="normal" font="default" size="100%">Sitarina Widyarini</style></author><author><style face="normal" font="default" size="100%">Shekhar Chhetri</style></author><author><style face="normal" font="default" size="100%">Muhammad Thohawi Elziyad Purnama</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Radiographic and Histological Evaluation in Canine Femur after Implantation of 304 Stainless-steel-based Plate</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">304 stainless-steel</style></keyword><keyword><style  face="normal" font="default" size="100%">Domesticated animal</style></keyword><keyword><style  face="normal" font="default" size="100%">Femur</style></keyword><keyword><style  face="normal" font="default" size="100%">Fracture</style></keyword><keyword><style  face="normal" font="default" size="100%">Radiograph</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2022</style></year><pub-dates><date><style  face="normal" font="default" size="100%">August 2022</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">14</style></volume><pages><style face="normal" font="default" size="100%">388-392</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;Fractures are known to be high-risk traumatic cases in domestic animals. Surgery was performed to reposition and immobilize bone using a plate as a biomaterial component. This study aimed to evaluate the radiographic and histological findings in canine femur after implantation of a 304 stainless-steel-based plate. A total of six male dogs aged 3-4 months were used in this study. Dogs were acclimatized for a week and then randomly assigned to 2 groups and 3 replication, respectively. The left femoral diaphysis was cracked and fixed by (A) commercial plate; (B) 304 stainless-steel plate. Radiographic observations were performed at 24 h and 28 d postoperatively during the recovery period. Histological figures were evaluated at 28 d postoperative descriptively. As a result, physical examination of muscle tissue in both groups did not reveal discoloration, swelling, and fluid accumulation around the plate. The radiographic figures presented a slight callus production around the crack and a decrease in the gap between cracks after 28 d. The histological figures observed the proliferation of osteoblasts, osteocytes, connective tissues, and bone trabeculae. It can be concluded that no significant difference between 304 stainlesssteel plate compared to commercial plate. A 304 stainless-steel-based plate is recommended for bone immobilization in canine femoral fractures.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Research Article </style></work-type><accession-num><style face="normal" font="default" size="100%">20</style></accession-num><section><style face="normal" font="default" size="100%">388</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Agus Purnomo&lt;sup&gt;1&lt;/sup&gt;, Hartiningsih&lt;sup&gt;1&lt;/sup&gt;, Setyo Budhi&lt;sup&gt;1&lt;/sup&gt;, Dhirgo Adji&lt;sup&gt;1&lt;/sup&gt;, Devita Anggraeni&lt;sup&gt;1&lt;/sup&gt;, Dito Anggoro&lt;sup&gt;1&lt;/sup&gt;, Sitarina Widyarini&lt;sup&gt;2&lt;/sup&gt;, Shekhar Chhetri&lt;sup&gt;3&lt;/sup&gt;, Muhammad Thohawi Elziyad Purnama&lt;sup&gt;4,5,*&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Veterinary Surgery and Radiology, Faculty of Veterinary Medicine, Universitas Gadjah Mada, Yogyakarta, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Veterinary Pathology, Faculty of Veterinary Medicine, Universitas Gadjah Mada, Yogyakarta, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Animal Science, College of Natural Resources, Royal University of Bhutan, Lobesa, Punakha, BHUTAN.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Division of Veterinary Anatomy, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;5&lt;/sup&gt;School of Health and Life Sciences, Universitas Airlangga, Surabaya, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Shafhan Dustur</style></author><author><style face="normal" font="default" size="100%">Joni Wahyuhadi</style></author><author><style face="normal" font="default" size="100%">Budi Utomo</style></author><author><style face="normal" font="default" size="100%">Muhammad Arifin Parenrengi</style></author><author><style face="normal" font="default" size="100%">Abdul Hafid Bajamal</style></author><author><style face="normal" font="default" size="100%">Sri Ratna Dwiningsih</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Relationship Histopathology Grading of Meningioma with the Use of Medroxyprogesterone Acetate (MPA) as A Hormonal Contraceptive</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Contraception</style></keyword><keyword><style  face="normal" font="default" size="100%">Grading</style></keyword><keyword><style  face="normal" font="default" size="100%">Hormonal contraceptive</style></keyword><keyword><style  face="normal" font="default" size="100%">Medroxyprogesterone acetate</style></keyword><keyword><style  face="normal" font="default" size="100%">Meningioma</style></keyword><keyword><style  face="normal" font="default" size="100%">MPA</style></keyword><keyword><style  face="normal" font="default" size="100%">Neoplasm.</style></keyword><keyword><style  face="normal" font="default" size="100%">Progesterone</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2022</style></year><pub-dates><date><style  face="normal" font="default" size="100%">January 2023</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">14</style></volume><pages><style face="normal" font="default" size="100%">938-941</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction&lt;/strong&gt;: Meningioma is a common brain tumor with an incidence of more than 30% of all primary brain tumors in adults. The incidence of meningiomas increases with increasing age, women suffer more from meningiomas with a ratio of 3:1. Meningiomas are known to have steroid receptors in the form of progesterone (88%), estrogen (40%), and androgen (40%). Therefore, the use of hormonal therapy is suspected to affect the incidence and histopathological degree of meningioma. One of the widely used hormonal therapy is &lt;em&gt;medroxyprogesterone&lt;/em&gt; &lt;em&gt;acetate&lt;/em&gt; (MPA). However, there is not enough literature to explain the relationship between MPA and the incidence of meningioma. Objective: To identify the relationship between the duration of the use of &lt;em&gt;Medroxyprogesterone acetate&lt;/em&gt; (MPA) hormonal contraceptives and the histopathological degree of meningioma.&lt;strong&gt; Methods:&lt;/strong&gt; This study is an analytic observational with a retrospective design of meningiomas patients based on the duration of use of MPAtype hormonal contraception who performed surgery at Dr. Soetomo General Academic Hospital during the period January 2015 to December 2019. We determined the inclusion criteria for meningioma patients: a history of using MPA hormonal contraceptives or 3-month injectable contraceptives; and the control group: meningioma patients without a history of hormonal contraception. &lt;strong&gt;Results: &lt;/strong&gt;There were 452 cases of meningioma and 101 patients met the inclusion criteria. Based on the results of statistical analysis, it was found that there was no difference relationship between the grade of meningioma and meningioma patients either using MPA or without using MPA. There was no difference in duration of use between the group using MPA &amp;lt;10 years or more than 10 years with the non-hormonal control group on meningioma grading (p = 0.772). There was also no difference relationship between the group that did not use hormonal contraception and the MPA group on the age of the patient (p = 0.217), both using contraception for &amp;lt;10 years and more than 10 years. &lt;strong&gt;Conclusion: &lt;/strong&gt;There was no relationship found between histopathological degree of meningioma with the patients who use MPA contraceptives, both duration of use &amp;lt;10 years and ≥10 years compared with meningioma patients who do not use MPA contraception.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6s</style></issue><work-type><style face="normal" font="default" size="100%">Original Article </style></work-type><section><style face="normal" font="default" size="100%">938</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Shafhan Dustur&lt;sup&gt;1&lt;/sup&gt;, Joni Wahyuhadi&lt;sup&gt;1,*&lt;/sup&gt;, Budi Utomo&lt;sup&gt;2&lt;/sup&gt;, Muhammad Arifin Parenrengi&lt;sup&gt;1&lt;/sup&gt;, Abdul Hafid Bajamal&lt;sup&gt;1&lt;/sup&gt;, Sri Ratna Dwiningsih&lt;sup&gt;3&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Neurosurgery, Universitas Airlangga – Dr. Soetomo General Academic Hospital, Surabaya, East Java, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Public Health and Community Medicine, Universitas Airlangga – Dr. Soetomo General Academic Hospital, Surabaya, East Java, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Obstetrics and Gynaecology, Universitas Airlangga – Dr. Soetomo General Academic Hospital, Surabaya, East Java, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Angelina V. Strelyaeva</style></author><author><style face="normal" font="default" size="100%">Anna G. Kharitonova</style></author><author><style face="normal" font="default" size="100%">Larisa B. Vaskova</style></author><author><style face="normal" font="default" size="100%">Alexander N. Luferov</style></author><author><style face="normal" font="default" size="100%">Dmitry O. Bokov</style></author><author><style face="normal" font="default" size="100%">Alina A. Bondar</style></author><author><style face="normal" font="default" size="100%">Natalia V. Bobkova</style></author><author><style face="normal" font="default" size="100%">Nevena Jeremic</style></author><author><style face="normal" font="default" size="100%">Yulia B. Lazareva</style></author><author><style face="normal" font="default" size="100%">Alla M. Antsyshkina</style></author><author><style face="normal" font="default" size="100%">Tatiana V. Prostodusheva</style></author><author><style face="normal" font="default" size="100%">Roman M. Kuznetsov</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Research on External Signs and Chemical Composition of Medicinal Plant Raw Material -Leaves of Ficus Elastica</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Chromato-mass spectrometry</style></keyword><keyword><style  face="normal" font="default" size="100%">Ficus elastic</style></keyword><keyword><style  face="normal" font="default" size="100%">Methyl</style></keyword><keyword><style  face="normal" font="default" size="100%">Phytol</style></keyword><keyword><style  face="normal" font="default" size="100%">Vitamin E.</style></keyword><keyword><style  face="normal" font="default" size="100%">б-D-Glucopyranoside</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2022</style></year><pub-dates><date><style  face="normal" font="default" size="100%">January 2023</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">14</style></volume><pages><style face="normal" font="default" size="100%">958-972</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;em&gt;Ficus elastica &lt;/em&gt;is a species of the plant in the genus Ficus, from the family Moraceae. &lt;em&gt;Ficus elastica,&lt;/em&gt; which is the object of our study, has been used for many years in phytodesign, however in terms of medicine, it remains a poorly studied plant. While studying the external signs and chemical composition of medicinal plant raw materials of leaves&lt;em&gt; Fícus elastica&lt;/em&gt;, chromato-mass spectrometry was used. During the process of studying, some diagnostic signs of&lt;em&gt; Ficus elastica&lt;/em&gt; were identified. Chromato-mass spectrometry was used to identify 68 compounds. The maximum amount was accounted for &lt;em&gt;б-D-Glucopyranoside&lt;/em&gt;, methyl (28,99%), Phytol (9,90%), 2-Hydroxy-3-methylsuccinic acid (6,93%), Lanosterol (6,13%), Hydroquinone (5,55%), 9,12,15-Octadecatrienoic acid, ethyl ester, (Z,Z,Z)- (4,86%), Lup-20(29)-en-3- one (4,17%), 1,2-Benzenediol (3,33%), Lupeol (2,95%), 16-Allopregnene-3б,9а-diol-20-one 3-O-acetate (2,77%), 9-Octadecenamide, (Z)- (2,67%), 9,12,15-Octadecatrienoic acid, (Z,Z,Z)- (2,05%), з-Sitosterol (1,84%), а-d-Lyxofuranoside, methyl (1,57%), Dasycarpidan-1-methanol, acetate (ester) (1,52%), n-Hexadecanoic acid (1,45%), Hexadecanoic acid, ethyl ester (1,33%), 1,8-Dioxacyclohexadecane-2,10- dione, 5,6:12,13-diepoxy-8,16-dimethyl- (1,15%), &lt;em&gt;Vitamin E&lt;/em&gt; (0,64%). Identified morphological features of the leaves of &lt;em&gt;Ficus elastica &lt;/em&gt;can be used in diagnosis of this species and may help to develop indicators of authenticity for promising medicinal leaves. As mentioned earlier, by means of chromato-mass spectrometry were identified 68 compounds, and the relative percentage of identified compounds was determined using a simple normalization method.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6s</style></issue><work-type><style face="normal" font="default" size="100%">Research Article </style></work-type><section><style face="normal" font="default" size="100%">958</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Angelina V. Strelyaeva&lt;sup&gt;1&lt;/sup&gt;, Anna G. Kharitonova&lt;sup&gt;1,*&lt;/sup&gt;, Larisa B. Vaskova&lt;sup&gt;1&lt;/sup&gt;, Alexander N. Luferov&lt;sup&gt;1&lt;/sup&gt;, Dmitry O. Bokov&lt;sup&gt;1&lt;/sup&gt;, Alina A. Bondar&lt;sup&gt;1&lt;/sup&gt;, Natalia V. Bobkova&lt;sup&gt;1&lt;/sup&gt;, Nevena Jeremic&lt;sup&gt;1,2&lt;/sup&gt;, Yulia B. Lazareva&lt;sup&gt;1&lt;/sup&gt;, Alla M. Antsyshkina&lt;sup&gt;1&lt;/sup&gt;, Tatiana V. Prostodusheva&lt;sup&gt;1&lt;/sup&gt;, Roman M. Kuznetsov&lt;sup&gt;1&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Sechenov First Moscow State Medical University, 8, Trubetskaya St., bldg. 2, 119991, Russian Federation, RUSSIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Pharmacy, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, SERBIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Swathi Priya K</style></author><author><style face="normal" font="default" size="100%">Rajasekaran S</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">RETRACTED: Phytochemical Screening, Gc-Ms Analysis and Antioxidant Activity of Marine Algae Obtained from Coastal Andhra Pradesh, India</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">DPPH</style></keyword><keyword><style  face="normal" font="default" size="100%">GCMS analysis</style></keyword><keyword><style  face="normal" font="default" size="100%">Physicochemical.</style></keyword><keyword><style  face="normal" font="default" size="100%">Spongomorpha indica</style></keyword><keyword><style  face="normal" font="default" size="100%">Superoxide</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2022</style></year><pub-dates><date><style  face="normal" font="default" size="100%">June 2022</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">14</style></volume><pages><style face="normal" font="default" size="100%">641-649</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;The Article has been Retracted based on the Authors' Request.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><accession-num><style face="normal" font="default" size="100%">23</style></accession-num><section><style face="normal" font="default" size="100%">641</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Swathi Priya K&lt;sup&gt;1,*&lt;/sup&gt;, Rajasekaran S&lt;sup&gt;2 &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Research Scholar, Department of Pharmacy, Bhagwant University, Sikar Rd, Ajmer, Rajasthan, INDIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of pharmacology, Bhagwant University, Sikar Rd, Ajmer, Rajasthan, INDIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Arifia Safira</style></author><author><style face="normal" font="default" size="100%">Prasita Widayani</style></author><author><style face="normal" font="default" size="100%">Dhiya An-Najaaty</style></author><author><style face="normal" font="default" size="100%">Cinta Atsa Mahesa Rani</style></author><author><style face="normal" font="default" size="100%">Mela Septiani</style></author><author><style face="normal" font="default" size="100%">Yan Arengga Syah Putra</style></author><author><style face="normal" font="default" size="100%">Tridiganita Intan Solikhah</style></author><author><style face="normal" font="default" size="100%">Aswin Rafif Khairullah</style></author><author><style face="normal" font="default" size="100%">Hartanto Mulyo Raharjo</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">A Review of an Important Plants: Annona squamosa Leaf</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Annona squamosa</style></keyword><keyword><style  face="normal" font="default" size="100%">Medicine</style></keyword><keyword><style  face="normal" font="default" size="100%">Pharmacology</style></keyword><keyword><style  face="normal" font="default" size="100%">Phytochemistry</style></keyword><keyword><style  face="normal" font="default" size="100%">Traditional medicinal plant</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2022</style></year><pub-dates><date><style  face="normal" font="default" size="100%">April 2022</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">14</style></volume><pages><style face="normal" font="default" size="100%">456-463</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;Plants have been utilized extensively in traditional medicine by a range of nations since ancient times, and more research into their safety, efficacy, and quality value is needed. One of the plants that have been widely used by society in traditional medicine is Annona squamosa L. &lt;em&gt;A. squamosa &lt;/em&gt;is commonly cultivated in tropical and subtropical regions. Based on previous research, all parts of&lt;em&gt; A. squamosa&lt;/em&gt; including bark, leaf, and roots have proven biological activities such as antioxidant, antifungal, and anticancer, especially on the leaves. Indian people have long history used young leaves of &lt;em&gt;A. squamosa &lt;/em&gt;for antidiabetic, besides in South China, they use seeds to decrease the cancer effect in the human body. The pharmacological activities of &lt;em&gt;A. squamosa&lt;/em&gt; leaves are antimicrobial, antifungal, anti-inflammatory, anticancer, antiulcer, antidiabetic, antidiarrheals, antiplatelet, antioxidant, and hepatoprotective, neuroprotective, and cytoprotective. Phytochemicals in &lt;em&gt;A. squamosa&lt;/em&gt; leaves include coumarins, tannins, cardiac glycosides, flavonoids, carbohydrates, and saponins. Meanwhile based on nutritional analysis shows that the &lt;em&gt;A. squamosa &lt;/em&gt;leaves are water, protein, lipids, Fiber Ash and Calcium.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Review Article</style></work-type><section><style face="normal" font="default" size="100%">456</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Arifia Safira&lt;sup&gt;1&lt;/sup&gt;, Prasita Widayani&lt;sup&gt;1&lt;/sup&gt;, Dhiya An-Najaaty&lt;sup&gt;1&lt;/sup&gt;, Cinta Atsa Mahesa Rani&lt;sup&gt;1&lt;/sup&gt;, Mela Septiani&lt;sup&gt;1&lt;/sup&gt;, Yan Arengga Syah Putra&lt;sup&gt;1&lt;/sup&gt;, Tridiganita Intan Solikhah&lt;sup&gt;1,*&lt;/sup&gt;, Aswin Rafif Khairullah&lt;sup&gt;2&lt;/sup&gt;, Hartanto Mulyo Raharjo&lt;sup&gt;3&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Division of Veterinary Clinic, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Doctoral Program in Veterinary Science, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Center of Excellence Fish Infectious Disease, Department of Veterinary Microbiology, Faculty of Veterinary Science, Chulalongkorn University, THAILAND.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Yelfi Anwar</style></author><author><style face="normal" font="default" size="100%">Gunawan Pasaribu</style></author><author><style face="normal" font="default" size="100%">M. Nazari V</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Review on Bioactive Potential of Indonesian Forest Essential Oils</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Bioactivity</style></keyword><keyword><style  face="normal" font="default" size="100%">Chemical compound</style></keyword><keyword><style  face="normal" font="default" size="100%">Essential oil</style></keyword><keyword><style  face="normal" font="default" size="100%">Indonesian forest</style></keyword><keyword><style  face="normal" font="default" size="100%">Pharmaceutics</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2022</style></year><pub-dates><date><style  face="normal" font="default" size="100%">December 2022</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">14</style></volume><pages><style face="normal" font="default" size="100%">873-879</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;Essential oils are composed of some natural, volatile, as well as aromatic compounds extracted from plants. In recent years, several studies have shown that some of their benefits can be attributed to their antimicrobial, antioxidant, anti-inflammatory, and also immunomodulatory properties. So, essential oils have been proposed as a common elective to anti-microbials or for utilize in combination with other antimicrobials against multidrug-resistant microscopic organisms. Most of the potential data about essential oils were obtained with in vitro and in vivo studies. Several types of essential oils are available in Indonesia which are reported to have biological activity such as antioxidants and antiaging are essential oils of pine (&lt;em&gt;Pinus merkusii&lt;/em&gt;), kilemo (Litsea cubeba), agarwood (&lt;em&gt;Aquilaria &lt;/em&gt;spp), eucalyptus (&lt;em&gt;Eucalyptus citriodora&lt;/em&gt;), and cinnamon (&lt;em&gt;Cinnamomum burmanii&lt;/em&gt;). The major chemical compound of pine oil is alpha pinene. Kilemo oil contains geranial. chemical marker compound of agarwood is chromone and sesquiterpenes. Eucalyptus contains citronella. The chemical component of cinnamon oil is cinnamaldehyde. Some essential oils have shown remarkable antioxidant activities when used at specific concentrations which can be due to their richness in phenolic compounds. However, toxicological studies are needed before any recommendation for application can be given. Preformulating and formulation studies will be needed to develop suitable dosage forms in order to introduce optimized pharmaceuticals (high active, low toxic) as alternative of current pharmaceutical dosage forms&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Review Article</style></work-type><section><style face="normal" font="default" size="100%">873</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Yelfi Anwar&lt;sup&gt;1,*&lt;/sup&gt;, Gunawan Pasaribu&lt;sup&gt;2&lt;/sup&gt;, M. Nazari V&lt;sup&gt;1&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;School of Pharmacy, University August 17, 1945, Jakarta, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Research Center for Biomass and Bioproducts, National Research and Innovation Agency, Jakarta, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Radebe Tlotlo</style></author><author><style face="normal" font="default" size="100%">Polo-Ma-Abiele Hildah Mfengwana</style></author><author><style face="normal" font="default" size="100%">Dedré Olivier</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Review on Literature of the Plant Elephantorrhiza Elephantine on its Healing Properties and Recent Acquired Knowledge of its Medicinal Activities (2000-2020)</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antimicrobial</style></keyword><keyword><style  face="normal" font="default" size="100%">Medicinal plants</style></keyword><keyword><style  face="normal" font="default" size="100%">Phytochemical content</style></keyword><keyword><style  face="normal" font="default" size="100%">Plant extracts.</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2022</style></year><pub-dates><date><style  face="normal" font="default" size="100%">June 2022</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">14</style></volume><pages><style face="normal" font="default" size="100%">715-721</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; The current review article outlines current findings in literature from undertaken studies and review articles on the plant &lt;em&gt;Elephantorrhiza elephantine&lt;/em&gt; from the past 20 years to date. The information presented in this article will include the following aspects of the plant. The plant description and taxomony, ethnomedical uses, phytochemistry and pharmacology of &lt;em&gt;Elephantorrhiza elephantine. &lt;/em&gt;The article looks to discuss existing hurdles in research found on this plant and how to integrate any previous research with what is currently done in research on the plant. It aims on guiding the path of future research direction on the plant &lt;em&gt;Elephantorrhiza elephantine&lt;/em&gt;.&lt;strong&gt; Methods:&lt;/strong&gt; A total of 40 articles were selected and read through. The articles selected had included literature publications with the keywords such as; &lt;em&gt;Elephantorrhiza elephantine,&lt;/em&gt; plant description, taxonomic of the plant, ethno medicinal usages, phytochemicals, pharmacological properties and plant toxicity, which were published between the years 2000 – 2021. There were 32 articles relevant for this review article and 2 dissertation that were written between the criteria of years.&lt;strong&gt; Results: &lt;/strong&gt;The ethomedicinal uses of &lt;em&gt;Elephantorrhiza elephantine&lt;/em&gt; have been investigated by various authors on the anti-microbial activities, anti-inflammatory, anticancer and in ethnoveterinary medicine on how the plant provides relief to individuals with illnesses/disease through its traditional uses. These studies have been conducted on both animals and humans. The experiments performed used the crude extract derived from parts of the plant such as the roots and leaves. These plant parts have phytochemical compounds that are extracted using varying polar solvents. In the animal studies, acetone extracts of &lt;em&gt;E. elephantine&lt;/em&gt; roots demonstrated significant activity against a tick-borne disease in cattle livestock and parasite worms in goats. In humans, the dried leaf extracts of &lt;em&gt;E. elephantine&lt;/em&gt; was also subjected to various polar solvents and water, investigated for phytochemical content, antioxidant, anti-inflammatory, anti-diabetic and cytotoxic activities, using standard methods. It was reported that the ethanol extract yielded the highest phytochemical content.&lt;strong&gt; Conclusion:&lt;/strong&gt; The gap in knowledge has narrowed on medicinal plants effects of healing properties. This lead by extensive research carried out trying to understand the benefits of traditional medication and why majority of the population uses it as they primary healthcare choice. Investigating the mechanism of action of &lt;em&gt;E. elephantine&lt;/em&gt; on its antimicrobial, anti-diabetic, antimalarial, anti-inflammatory and wound healing could lead to an enhanced understanding on the medicinal properties of the plant extracts and a commercialisation of a product in future.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Review Article</style></work-type><accession-num><style face="normal" font="default" size="100%">31</style></accession-num><section><style face="normal" font="default" size="100%">715</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Radebe Tlotlo&lt;sup&gt;1,*&lt;/sup&gt;, Polo-Ma-Abiele Hildah Mfengwana&lt;sup&gt;2&lt;/sup&gt;, Dedré Olivier&lt;sup&gt;3&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Health Sciences, Faculty of Health and Environmental Sciences, Central University of Technology, P/Bag X20539, Bloemfontein, 9300, SOUTH AFRICA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Health Sciences, Faculty of Health and Environmental Sciences, Central University of Technology, P/Bag X20539, Bloemfontein, 9300, SOUTH AFRICA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Health Sciences, Faculty of Health and Environmental Sciences, Central University of Technology, P/Bag X20539, Bloemfontein, 9300, SOUTH AFRICA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Agniya Ali Fahmi Hikmat</style></author><author><style face="normal" font="default" size="100%">Mia Ratwita Andarsini</style></author><author><style face="normal" font="default" size="100%">Bagus Setyoboedi</style></author><author><style face="normal" font="default" size="100%">Maria Christina Shanty Larasati</style></author><author><style face="normal" font="default" size="100%">Andi Cahyadi</style></author><author><style face="normal" font="default" size="100%">I Dewa Gede Ugrasena</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Risk Factors for Hepatotoxicity From L-Asparaginase Chemotherapy In Children With Acute Lymphoblastic Leukemia</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Acute lymphoblastic leukemia</style></keyword><keyword><style  face="normal" font="default" size="100%">Children</style></keyword><keyword><style  face="normal" font="default" size="100%">Hepatotoxicity</style></keyword><keyword><style  face="normal" font="default" size="100%">L-asparaginase</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2022</style></year><pub-dates><date><style  face="normal" font="default" size="100%">January 2023</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">14</style></volume><pages><style face="normal" font="default" size="100%">921-927</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; L-asparaginase chemotherapy often causes hepatotoxicity and affects complete remission in pediatric acute lymphoblastic leukemia (ALL). This study aims to investigate the risk factors that affect the incidence of hepatotoxicity caused by L-asparaginase chemotherapy in ALL children. &lt;strong&gt;Methods:&lt;/strong&gt; An observational study with prospective sampling was conducted at Dr. Soetomo Hospital, Surabaya. The inclusion criteria included ALL children aged 1-18 years, undergoing ALL Induction phase chemotherapy based on the 2018 Indonesian Children's ALL protocol as evidenced by bone marrow aspiration, receiving L-asparaginase chemotherapy, and obtaining written consent from parents or guardians. Each child had 3 ml of blood drawn from a peripheral vein to assess their complete blood count, alanine transaminase (ALT) levels, and albumin level. &lt;strong&gt;Results:&lt;/strong&gt; Thirty-two children with ALL were collected. Two of them were excluded due to allergic reaction and enable to continue the L-asparaginase chemotherapy. Thirty of them were eligible participants. Approximately 53.3% of ALL children aged ≤ seven years. Fourteen (47%) children with ALL were included in the standard-risk group and 16 (53%) of them included high-risk group. There were significant differences in ALT levels between the four stages of observation (p=&amp;lt;0.001). Twenty-two ALL children had hepatotoxicity (73.3%), while 8 had non-hepatotoxicity (26.7%). Two risk factors had a significant influence on the occurrence of hepatotoxicity due to L-asparaginase chemotherapy including age and hypoalbuminemia (p=0.045, p=0.028). &lt;strong&gt;Conclusion:&lt;/strong&gt; Age and hypoalbuminemia were the risk factors that might affect the incidents of hepatotoxicity. Clinical monitoring before and after treatment needs to be done to prevent poor outcomes.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6s</style></issue><work-type><style face="normal" font="default" size="100%">Original Article </style></work-type><section><style face="normal" font="default" size="100%">921</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Agniya Ali Fahmi Hikmat&lt;sup&gt;1&lt;/sup&gt;, Mia Ratwita Andarsini&lt;sup&gt;1,2,*&lt;/sup&gt;, Bagus Setyoboedi&lt;sup&gt;1,2&lt;/sup&gt;, Maria Christina Shanty Larasati&lt;sup&gt;1,2&lt;/sup&gt;, Andi Cahyadi&lt;sup&gt;1,2&lt;/sup&gt;, I Dewa Gede Ugrasena&lt;sup&gt;1,2&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Child Health, Faculty of Medicine Universitas Airlangga, Surabaya, East Java, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Dr. Soetomo General Academic Teaching Hospital, Surabaya, East Java, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Ditya Indrawati</style></author><author><style face="normal" font="default" size="100%">Linda Astari</style></author><author><style face="normal" font="default" size="100%">Afif Nurul Hidayati</style></author><author><style face="normal" font="default" size="100%">Sawitri, Damayanti</style></author><author><style face="normal" font="default" size="100%">Budi Utomo</style></author><author><style face="normal" font="default" size="100%">Bagus Haryo Kusumaputra</style></author><author><style face="normal" font="default" size="100%">Medhi Denisa Alinda</style></author><author><style face="normal" font="default" size="100%">Cita Rosita Sigit Prakoeswa</style></author><author><style face="normal" font="default" size="100%">M. Yulianto Listiawan</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Risk Factors of Acute and Chronic Erythema Nodosum Leprosum in Dr. Soetomo General Academic Hospital Surabaya</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Acute ENL</style></keyword><keyword><style  face="normal" font="default" size="100%">Chronic ENL</style></keyword><keyword><style  face="normal" font="default" size="100%">ENL</style></keyword><keyword><style  face="normal" font="default" size="100%">Leprosy</style></keyword><keyword><style  face="normal" font="default" size="100%">Neglected disease.</style></keyword><keyword><style  face="normal" font="default" size="100%">Risk factors</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2022</style></year><pub-dates><date><style  face="normal" font="default" size="100%">December 2022</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">14</style></volume><pages><style face="normal" font="default" size="100%">766-770</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; Leprosy is a chronic granulomatous infection and is one of the neglected diseases caused by &lt;em&gt;Mycobacterium leprae.&lt;/em&gt; ENL is a complex syndrome, that caused inflammation of the skin, nerves, and other organs due to an inflammatory immune response to &lt;em&gt;Mycobacterium leprae &lt;/em&gt;antigens. Acute ENL was defined as the first episode of ENL with a duration of less than 24 weeks. Chronic ENL was defined as ENL that persisted for more than 24 weeks. These types of ENL can have different risk factors and require different therapeutic interventions. Purpose: The onset of ENL is acute, but may progress to a chronic or recurrent phase and require long-term therapy. Early detection of leprosy is very important, because the infection is curable and prompt treatment can reduce nerve damage and associated stigma. Chronic ENL patients require prolonged high doses of corticosteroids to control inflammation in ENL and cause severe complications and side effects associated with morbidity and mortality.&lt;strong&gt; Methods: &lt;/strong&gt;This retrospective study was conducted using a non-probability sampling technique consecutively using a casecontrol formula in leprosy patients with ENL in the Leprosy Division of the Outpatient Dermatology and Venereology Unit RSUD Dr. Soetomo Surabaya for the period 2015 – 2020, using secondary data in the form of medical record data.&lt;strong&gt; Result: &lt;/strong&gt;The results of this study obtained leprosy patients with ENL as many as 234 patients, 56 patients with acute ENL and 89 patients with chronic ENL. 45 patients with acute ENL and 45 patients with chronic ENL were obtained from the case-control minimal sample size formula. &lt;strong&gt;Conclusion:&lt;/strong&gt; The results of the bivariate analysis test showed that there was a relationship between risk factors for coinfection and steroid therapy with the type of ENL. The presence of coinfection and steroid therapy showed that patients tend to be chronic ENL, conversely, in the absence of coinfection and without steroid therapy, patients tend to be acute ENL. The multivariate logistic regression analysis test showed a significant association between risk factors for ENL onset before MDT and the presence of coinfection with chronic ENL, whereas ENL onset after MDT and absence of coinfection were associated with acute ENL.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">766</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Ditya Indrawati, Linda Astari, Afif Nurul Hidayati, Sawitri, Damayanti, Budi Utomo, Bagus Haryo Kusumaputra, Medhi Denisa Alinda, Cita Rosita Sigit Prakoeswa, M. Yulianto Listiawan*&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;Resident of Dermatology and Venereology, Faculty of Medicine, Universitas Airlangga/ Dr. Soetomo General Academic Hospital, Surabaya, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Olivia Mahardani Adam</style></author><author><style face="normal" font="default" size="100%">Widjiati Widjiati</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Role of Alkaloid on Platelet Aggregation and Serotonin in Migraine</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Alkaloid</style></keyword><keyword><style  face="normal" font="default" size="100%">Migraine</style></keyword><keyword><style  face="normal" font="default" size="100%">Platelet</style></keyword><keyword><style  face="normal" font="default" size="100%">Platelet aggregation</style></keyword><keyword><style  face="normal" font="default" size="100%">Serotonin.</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2022</style></year><pub-dates><date><style  face="normal" font="default" size="100%">June 2022</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">14</style></volume><pages><style face="normal" font="default" size="100%">629-632</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;Migraine is a sterile neurogenic inflammation of the trigeminal nerve which releases vasoactive neuropeptides and activates platelets to release vasoactive substances such as serotonin (5-HT). Platelet hyperaggregation occurs in the pathogenesis of migraine caused by one of the stimulatory factors 5-HT. Platelet aggregation is increased and 5-HT levels are elevated in the blood and brain in the early stages of migraine. Alkaloid β-carbolin alkaloids can increase monoamines in brain regions through inhibition of monoamine oxidase (MAO) and inhibition of 5-HT reuptake. Alkaloids in the ethanolic extract of SCE function as analgesics and anti-inflammatory which can reduce pain and improve blood circulation. &lt;em&gt;Sargassum cristaefolium&lt;/em&gt; extract (SCE) was measured for its bioactive substance content. The extract was administered to an animal model of intraperitoneal nitroglycerin-induced migraine and examined for platelet levels, platelet aggregation and 5-HT. The results of statistical tests showed an increase in platelets (p&amp;lt;0.05), an increase in platelet aggregation (p&amp;lt;0.05) and a decrease in 5-HT (p&amp;lt;0.05). The relationship between alkaloids and platelets; platelets and platelet aggregation; platelet aggregation and 5-HT and 5-HT levels and migraine incidence (p&amp;lt;0.05). The alkaloids found in SCE can lower platelet count, decrease platelet aggregation and increase 5-HT levels in migraines.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><accession-num><style face="normal" font="default" size="100%">21</style></accession-num><section><style face="normal" font="default" size="100%">629</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Olivia Mahardani Adam&lt;sup&gt;1,*&lt;/sup&gt;, Widjiati Widjiat&lt;sup&gt;i2&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Neurology, Faculty of Medicine, Universitas Hang Tuah, Surabaya, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Laboratory of Embryology, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Tita Natalia Manurung</style></author><author><style face="normal" font="default" size="100%">Citrawati Dyah Kencono Wungu</style></author><author><style face="normal" font="default" size="100%">Martono Tri Utomo</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">The Role of Breast Milk on Reducing the Risk of Neonatal Sepsis in Preterm and Low Birth Weight Infants: A Systematic Review and Meta-Analysis</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Breast milk</style></keyword><keyword><style  face="normal" font="default" size="100%">Low birth weight</style></keyword><keyword><style  face="normal" font="default" size="100%">Neonatal sepsis</style></keyword><keyword><style  face="normal" font="default" size="100%">Preterm infant</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2022</style></year><pub-dates><date><style  face="normal" font="default" size="100%">January 2023</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">14</style></volume><pages><style face="normal" font="default" size="100%">1067-1074</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; High mortality and morbidity rates are associated with neonatal sepsis in preterm and low birth weight infants. Aside from controlling the nosocomial infection, intervention for reducing the risk of sepsis is demanded. The best nutrition for preterm infants is breast milk. Bioactive compounds found in it, such as antibacterial, antiviral, and anti-inflammatory activities not only for immunity against the infection but also for growth, and development. &lt;strong&gt;Objective: &lt;/strong&gt;To investigate the effect of breast milk against the risk of neonatal sepsis in preterm and low birth weight infants. &lt;strong&gt;Methods:&lt;/strong&gt; We conducted an electronic search through several databases including PubMed, Web of Science, Science Direct, and Scopus. We performed an analysis on nutritional feeding and volume of breast milk and late-onset sepsis from ten potential observational studies. &lt;strong&gt;Results:&lt;/strong&gt; Breast milk significantly reduced the risk of sepsis in preterm and low birth weight infants (pooled RR 0.70; 95 % CI 0.55 - 0.88, p = 0.002). In addition, when we performed subgroup analysis, we found that breast milk volume &amp;gt; 50ml/kgbw/day also reduce the risk of sepsis with pooled RR 0.61(95% CI 0.46-0.8, p=0.0004). &lt;strong&gt;Conclusion:&lt;/strong&gt; Low birth weight and preterm infants had a lower risk of neonatal sepsis when they got breastmilk. To preserve the supply of breastmilk, health professionals should support and encourage mothers who were breastfeeding.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6s</style></issue><work-type><style face="normal" font="default" size="100%">Review Article</style></work-type><section><style face="normal" font="default" size="100%">1067</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Tita Natalia Manurung&lt;sup&gt;1&lt;/sup&gt;, Citrawati Dyah Kencono Wungu&lt;sup&gt;2,*&lt;/sup&gt;, Martono Tri Utomo&lt;sup&gt;1&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Child Health, Faculty of Medicine, Universitas Airlangga, Surabaya, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Departement of Biochemistry, Faculty of Medicine, Universitas Airlangga, Surabaya, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Akram A Hammo</style></author><author><style face="normal" font="default" size="100%">Abdulla A Ahmad</style></author><author><style face="normal" font="default" size="100%">Zeina A Althanoon</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Role of Gender in the Protection Against Doxorubicin-Induced Oxidative Stress</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Coenzyme Q10</style></keyword><keyword><style  face="normal" font="default" size="100%">Doxorubicin</style></keyword><keyword><style  face="normal" font="default" size="100%">Gender difference</style></keyword><keyword><style  face="normal" font="default" size="100%">Oxidative stress</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2022</style></year><pub-dates><date><style  face="normal" font="default" size="100%">December 2022</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">14</style></volume><pages><style face="normal" font="default" size="100%">782-788</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; There are gender differences in the oxidation-reduction reactions. Doxorubicin (Dox) is a chemotherapeutic drug that can produce oxidative stress which may require prevention by antioxidants. Aim: The study aimed to investigate the gender-dependent changes in Dox-induced oxidative stress, and the protective effects of coenzyme Q10 (CoQ10).&lt;strong&gt; Materials and Methods&lt;/strong&gt;: Rats were administered CoQ10 orally for 17 days. On day 13, some rats receiving CoQ10 received a single intraperitoneal dosage of Dox, whereas other rats received normal saline. Glutathione (GSH), malondialdehyde (MDA), and total anti-oxidant capacity (T-AOC) were measured in both genders of albino rats. &lt;strong&gt;Results&lt;/strong&gt;: Dox significantly reduced both GSH and T-AOC levels and caused a significant increase in MDA. The administration of CoQ10 significantly prevented these changes. Dox caused a larger reduction in GSH in males than in females, while CoQ10 caused more protection in females. Dox caused a higher increase in MDA levels in males.&lt;strong&gt; Conclusion:&lt;/strong&gt; Pre-treatments with CoQ10 may protect against Dox-induced oxidative stress, with gender-dependent variations in the extent of these Dox/CoQ10 effects.&lt;/p&gt;
&lt;quillbot-extension-portal&gt;&lt;/quillbot-extension-portal&gt;</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Research Article </style></work-type><section><style face="normal" font="default" size="100%">782</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Akram A Hammo&lt;sup&gt;1&lt;/sup&gt;, Abdulla A Ahmad&lt;sup&gt;2,*&lt;/sup&gt;, Zeina A Althanoon&lt;sup&gt;3&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;The primary health care sector in Al-Baaj, Nineveh Health Directorate, Ministry of Health, IRAQ.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of clinical and laboratory sciences, College of Pharmacy, University of Mosul, IRAQ.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of pharmacology and toxicology, College of Pharmacy, University of Mosul, IRAQ&lt;/p&gt;
&lt;quillbot-extension-portal&gt;&lt;/quillbot-extension-portal&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Skunda Diliarosta</style></author><author><style face="normal" font="default" size="100%">Sudarmin</style></author><author><style face="normal" font="default" size="100%">Annisa Efendi</style></author><author><style face="normal" font="default" size="100%">Dwisari Dillasamola</style></author><author><style face="normal" font="default" size="100%">Biomechy Oktomalioputri</style></author><author><style face="normal" font="default" size="100%">Rehani Ramadhani</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Reconstruction and Scientific Explanation of Akar Kuning (Arcangelisia flava Merr.) From West Sumatra as Ethnomedicine and Source of Science Learning</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Akar Kuning (Arcangelisia flava Merr.)</style></keyword><keyword><style  face="normal" font="default" size="100%">Ethnoscience</style></keyword><keyword><style  face="normal" font="default" size="100%">Reconstruction</style></keyword><keyword><style  face="normal" font="default" size="100%">Scientific explanation</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2021</style></year><pub-dates><date><style  face="normal" font="default" size="100%">January 2021</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">13</style></volume><pages><style face="normal" font="default" size="100%">206-211</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;Indonesia is one of the countries that has the largest tropical forest land in the world, this makes Indonesia rich in diversity of flora and fauna. This diversity produces a variety of cultures, traditions and local wisdom. One of the local wisdoms of the people of West Sumatra is the use and utilization of the biodiversity around it as a medicine for various diseases. The type of medicinal plant that is the focus of this research is the type of Akar Kuning plant (&lt;em&gt;Arcangelisia &lt;/em&gt;flava Merr.). This research is an educational research conducted using an ethnoscience approach, meaning that it is based on the indigenous knowledge of the local community. This study aims to reconstruct knowledge from a cultural / community perspective in the health sector. which later will become a knowledge with scientific explanation. The data were obtained through direct observation to the research location regarding indigenous knowledge about the Akar Kuning plant and also based on laboratory test data on antibacterial activity carried out in the biology laboratory of Semarang State University. All data obtained will be analyzed and also strengthened by various sources. The analysis concluded that the Akar Kuning (&lt;em&gt;Arcangelisia&lt;/em&gt; flava Merr.) Plant contains bioactive compounds that act as antibacterials, thus inhibiting bacterial growth. This is evidenced by the inhibition zone diameter data produced during laboratory tests showing the results that the Yellow Root plant extract (&lt;em&gt;Arcangelisia&lt;/em&gt; flava Merr.)&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">206</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Skunda Diliarosta&lt;sup&gt;1,&lt;/sup&gt;*, Sudarmin&lt;sup&gt;2&lt;/sup&gt;, Annisa Efendi&lt;sup&gt;3&lt;/sup&gt;, Dwisari Dillasamola&lt;sup&gt;1&lt;/sup&gt;, Biomechy Oktomalioputri&lt;sup&gt;4&lt;/sup&gt;, Rehani Ramadhani&lt;sup&gt;4&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Science Education, Universitas Negeri Padang, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Chemistry Department, Faculty of Mathematics and Natural Science, Semarang State University, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Pharmacology department, Faculty of Pharmacy, Andalas University, INDONESIA. 4Histology Department, Faculty of Medicine, Andalas University, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Herin Setianingsih</style></author><author><style face="normal" font="default" size="100%">Satria Erda Wisnumarta</style></author><author><style face="normal" font="default" size="100%">Sareh Arjono Tjandra</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Repairing of Renal Tubules in Diabetic Rats (Rattus norvegicus) Diabetes After Administration of Golden Sea Cucumber (Stichopus hermanii)</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Diabetic rat</style></keyword><keyword><style  face="normal" font="default" size="100%">Stichopus hermanii</style></keyword><keyword><style  face="normal" font="default" size="100%">Tubular injury</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2021</style></year><pub-dates><date><style  face="normal" font="default" size="100%">July 2021</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">13</style></volume><pages><style face="normal" font="default" size="100%">958-964</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;This study aims to analyze the improvement of the histopathological picture of renal tubules in diabetic rats after being given golden sea cucumber extract (&lt;em&gt;Stichopus hermanii&lt;/em&gt;). This research uses experimental design laboratories with a post-test only control group design method. The sampling used simple random sampling with 25 white rats divided into five groups, namely groups that were given standard feed without STZ-induced, STZ-induced group, STZ-induced group and given golden sea cucumber extract at a dose of 4.25 mg/kg BW for 21 days, STZinduced group and given golden sea cucumber extract at a dose of 8.5 mg/kg BW for 21 days, and STZ-induced group and given gold sea cucumber extract at a dose of 12.75 mg/kg BW for 21 days. The data on the observation of each group's kidney histopathology was carried out at the end of the session. The results of the analysis using the Kruskal-Wallis Test showed significant results, the Mann-Whitney Test showed significant differences between the STZinduced group and the golden sea cucumber extract (&lt;em&gt;Stichopus hermanii&lt;/em&gt;) dose of 12.75 mg/kg BW (x=7.4 mg/dl) decreased significantly (p=0.001) compared to the STZ-only-induced group (x=12.6 mg/dl). Administration of golden sea cucumber extract (&lt;em&gt;Stichopus hermanii&lt;/em&gt;) at a dose of 12.75 mg/kg BW of rats for 21 days lowered the degree of tubular damage to the kidney rectus of white rats (&lt;em&gt;Rattus norvegicus&lt;/em&gt;) male streptozotocin-induced strains.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">958</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Herin Setianingsih*, Satria Erda Wisnumarta, Sareh Arjono Tjandra&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;Faculty of Medicine, Universitas Hang Tuah, Surabaya, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Ehab M Mostafa</style></author><author><style face="normal" font="default" size="100%">Mohammed Gamal</style></author><author><style face="normal" font="default" size="100%">Mohammed M Ghoneim</style></author><author><style face="normal" font="default" size="100%">Shaimaa Hussein</style></author><author><style face="normal" font="default" size="100%">Ahmed H El-Ghorab</style></author><author><style face="normal" font="default" size="100%">Mohamed A Abdelgawad</style></author><author><style face="normal" font="default" size="100%">Arafa Musa</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Repurposing of FDA Approved Alkaloids as COVID 19 Inhibitors; in silico Studies</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Alkaloids</style></keyword><keyword><style  face="normal" font="default" size="100%">COVID-19</style></keyword><keyword><style  face="normal" font="default" size="100%">Docking study</style></keyword><keyword><style  face="normal" font="default" size="100%">FDA</style></keyword><keyword><style  face="normal" font="default" size="100%">Natural drugs</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2021</style></year><pub-dates><date><style  face="normal" font="default" size="100%">January 2021</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">13</style></volume><pages><style face="normal" font="default" size="100%">110-123</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background: &lt;/strong&gt;Alkaloid drugs were permitted for using as a treatment of numerous diseases. Colchicine, codeine, piperine, papaverine, ergometrine, theophylline, theobromine and caffeine are recognized safe alkaloids and used for many human disfunctions. The chemical structures of alkaloids have flexible chemical moieties with various electronic and chemical characters. COVID-19 is a horrible disease as result from that the discovering of potent drugs from previously FDA approved drugs is the main objective of this study. &lt;strong&gt;Methods:&lt;/strong&gt; docking studies were used for discovering the interactions of alkaloids with protease proteins. The nature of selected alkaloids structures was utilized for advance insights studies to predict new medical applications. &lt;strong&gt;Results: &lt;/strong&gt;Docking studies for alkaloids were completed and the obtained outcomes, displayed that all tried alkaloids have great attraction with the five protease proteins, the energy docking score ranged from -2.9516 (for colchicine with 5R82) to -24.7449 (for ergotamine with 5R80) kcal/mol with 1-5 variable interactions bond. &lt;strong&gt;Conclusion: &lt;/strong&gt;Among the tested drugs, papaverine and ergometrine revealed high docking scores for all five proteins (score ranged from, -14.1058 to 23.1619 for papaverine and, -4.7900 to 24.7449 for ergometrine) and number of interactions with all tested proteins are two to three for papaverine but for ergometrine are two to five.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">110</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Ehab M. Mostafa&lt;sup&gt;1&lt;/sup&gt;, Mohammed Gamal&lt;sup&gt;2&lt;/sup&gt;, Mohammed M. Ghoneim&lt;sup&gt;3&lt;/sup&gt;, Shaimaa Hussein&lt;sup&gt;4&lt;/sup&gt;, Ahmed H. El-Ghorab&lt;sup&gt;5&lt;/sup&gt;, Mohamed A. Abdelgawad&lt;sup&gt;2,&lt;/sup&gt;*, Arafa Musa&lt;sup&gt;1&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Pharmacognosy Department, College of Pharmacy, Jouf University, Sakaka, Aljouf, 72341, KSA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Pharmaceutical Chemistry, College of Pharmacy, Jouf University, Sakaka, 72341, KSA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Pharmacy, College of Pharmacy, Al Maarefa University, Ad Diriyah 13713, SAUDI ARABIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Department of Pharmacology, College of Pharmacy, Jouf University, Sakaka, Aljouf 72341, SAUDI ARABIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;5&lt;/sup&gt;Chemistry Department, College of Science, Jouf university, Sakaka, Aljouf 72341, SAUDI ARABIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Gagan Tiwana</style></author><author><style face="normal" font="default" size="100%">Jiahe Fua</style></author><author><style face="normal" font="default" size="100%">Lanping Lu</style></author><author><style face="normal" font="default" size="100%">Matthew J Cheesman</style></author><author><style face="normal" font="default" size="100%">IE.Cock</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">A Review of the Traditional Uses, Medicinal Properties and Phytochemistry of Centaurea benedicta L.</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Asteraceae</style></keyword><keyword><style  face="normal" font="default" size="100%">Blessed thistle</style></keyword><keyword><style  face="normal" font="default" size="100%">Flavonoids</style></keyword><keyword><style  face="normal" font="default" size="100%">St Benedict’s thistle</style></keyword><keyword><style  face="normal" font="default" size="100%">Tannins</style></keyword><keyword><style  face="normal" font="default" size="100%">Terpenoids</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2021</style></year><pub-dates><date><style  face="normal" font="default" size="100%">May 2021</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">13</style></volume><pages><style face="normal" font="default" size="100%">798-812</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;em&gt;Centaurea benedicta&lt;/em&gt; L. is an annual herbaceous plant which belongs to the Asteraceae family. It is native to the Mediterranean region and western Asia and is commonly known as blessed thistle, holy thistle, St Benedict’s thistle or spotted thistle. Traditionally, it has been used to treat bubonic plague and possesses diuretic, galactagogue, liver-strengthening and wound healing properties. Recent research studies have investigated its anticancer, antiinflammatory, antioxidant and other therapeutic properties. Several studies have also reported its antimicrobial activity against a range of bacterial pathogens. However, most of these studies were preliminary and only tested relatively high concentrations of the extracts. Additionally, most studies screened a limited number of pathogens. Cnicin is the main chemical compound present in &lt;em&gt;C. benedicta &lt;/em&gt;and it has been widely investigated. However, few other compounds from this plant have been identified and/or investigated, and further phytochemical studies are warranted. Interestingly, pure cnicin has good anticancer activity, whilst the crude extracts lack cytotoxic properties. Phytochemical analyses of&lt;em&gt; C. benedicta &lt;/em&gt;extracts reveal the presence of multiple flavonoids, tannins, terpenoids and lactones, although few specific phytochemicals within these phytochemical classes have been identified. A limited number of research studies have determined the toxicity profile of &lt;em&gt;C. benedicta &lt;/em&gt;in order to evaluate its safety for human use. Substantially more detailed studies are required to rigorously investigate the therapeutic properties and phytochemistry of &lt;em&gt;C. benedicta&lt;/em&gt;, which may ultimately lead to the development of new plant-based therapeutic medicines.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Review Article</style></work-type><section><style face="normal" font="default" size="100%">798</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Gagan Tiwana&lt;sup&gt;1,2&lt;/sup&gt;, Jiahe Fua&lt;sup&gt;2&lt;/sup&gt;, Lanping Lu&lt;sup&gt;2&lt;/sup&gt;, Matthew J. Cheesman&lt;sup&gt;1,3&lt;/sup&gt;, I.E.Cock&lt;sup&gt;2,4,&lt;/sup&gt;*&amp;nbsp;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;School of Pharmacy and Pharmacology, Gold Coast Campus, Griffith University, Parklands Drive, Southport, Queensland 4222, AUSTRALIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;School of Natural Sciences, Nathan Campus, Griffith University, Brisbane, AUSTRALIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Menzies Health Institute Queensland, Quality Use of Medicines Network, Queensland 4222, AUSTRALIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Environmental Futures Research Institute, Nathan Campus, Griffith University, Brisbane, AUSTRALIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Wan Nor Iffah Husna Wan Mustaffa</style></author><author><style face="normal" font="default" size="100%">Wan Hafizah W. Jusof</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">A Review on Antioxidant and Antidiabetic Activities of Nephelium Lappaceum L.</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antidiabetic</style></keyword><keyword><style  face="normal" font="default" size="100%">Antioxidant</style></keyword><keyword><style  face="normal" font="default" size="100%">Diabetes mellitus</style></keyword><keyword><style  face="normal" font="default" size="100%">Nephelium lappaceum L.</style></keyword><keyword><style  face="normal" font="default" size="100%">Phytoconstituents</style></keyword><keyword><style  face="normal" font="default" size="100%">Rambutan</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2021</style></year><pub-dates><date><style  face="normal" font="default" size="100%">July 2021</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">13</style></volume><pages><style face="normal" font="default" size="100%">1053-1057</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;Diabetes mellitus is a chronic disease that occurs in the majority of people worldwide. The number of cases in many countries has been increasing year by year. In Malaysia, the statistics show that the number of diabetic case in 2019 was 3.6 million and expected to increase in 2025 by 7 million. This disease can develop as a result of oxidative stress production in the body. &lt;em&gt;Nephelium lappaceum &lt;/em&gt;was claimed traditionally being used to treat diabetes mellitus. This research is conducted to review the available literature regarding the antioxidant and antidiabetic activities of &lt;em&gt;Nephelium lappaceum&lt;/em&gt; extracts and constituent that contributes to this activity. &lt;strong&gt;Methods:&lt;/strong&gt; The studies included in this review have been selected using several databases including Google Scholar, Wiley Online Library, Science Direct and Pubmed. The keywords used in database search were “&lt;em&gt;Nephelium lappaceum&lt;/em&gt;”, “antioxidant” and “antidiabetic” and covered the period from 2007 onwards. &lt;strong&gt;Results:&lt;/strong&gt; This review revealed that &lt;em&gt;Nephelium lappaceum&lt;/em&gt; extracts have good antioxidant and antidiabetic activities when tested using various methods. These activities are due to the presence of several phytoconstituents in the extract. &lt;strong&gt;Conclusions:&lt;/strong&gt; In conclusion, &lt;em&gt;Nephelium lappaceum &lt;/em&gt;possess antioxidant and antidiabetic activities. It has the potential to be developed as an antidiabetic and antioxidant agent which can be used to treat various oxidative stress-related diseases, including diabetes mellitus.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Review Article</style></work-type><section><style face="normal" font="default" size="100%">1053</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Wan Nor Iffah Husna Wan Mustaffa, Wan Hafizah W. Jusof*&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;Faculty of Pharmacy and Health Sciences, Universiti Kuala Lumpur Royal College of Medicine Perak, Ipoh, MALAYSIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Mohammad Sukmanadi</style></author><author><style face="normal" font="default" size="100%">Mustofa Helmi Effendi</style></author><author><style face="normal" font="default" size="100%">Faisal Fikri</style></author><author><style face="normal" font="default" size="100%">Muhammad Thohawi Elziyad Purnama</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Role of Capsaicin in the Repair of Cellular Activity in Mice Liver</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Aflatoxin B1</style></keyword><keyword><style  face="normal" font="default" size="100%">Animal</style></keyword><keyword><style  face="normal" font="default" size="100%">Capsaicin</style></keyword><keyword><style  face="normal" font="default" size="100%">Fibroblast.</style></keyword><keyword><style  face="normal" font="default" size="100%">Kupffer cell</style></keyword><keyword><style  face="normal" font="default" size="100%">Stellate</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2021</style></year><pub-dates><date><style  face="normal" font="default" size="100%">December 2021</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">13</style></volume><pages><style face="normal" font="default" size="100%">1573-1576</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;This study aimed to determine the capsaicin efficacy on Kupffer cell, polymorphonuclear, stellate, and fibroblast cells in mice liver induced with aflatoxin B1. A total of 20 mice were used as sample, assigned into four group i.e. (T0) administered 0,5 ml of polyethylene glycol, (T1) administered 0,5 ml of capsaicin + 0,5 ml of polyethylene glycol, (T2) administered 0,1 ml of aflatoxin B1 + 0,5 ml of polyethylene glycol, (T3) administered 0,1 ml of aflatoxin B1 + 0,5 ml of capsaicin, respectively. All treatment were done for a month then followed by liver dissection for hematoxylin eosin staining. The differential cells counted then analyzed using ANOVA and Tukey multiple comparison test (p&amp;lt;0,05). The cell determination showed that Kupffer cell, polymorphonuclear, stellate, and fibroblast cells decreased significantly (p&amp;lt;0,05) in T3 group compared to T2 group. Meanwhile, the T1 group showed similar (p&amp;gt;0,05) with T0 group. It can be concluded that capsaicin has a potential effect to improve cellular activity in mice liver with aflatoxin B1 toxication.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6s</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">1573</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Mohammad Sukmanadi&lt;sup&gt;1&lt;/sup&gt;, Mustofa Helmi Effendi&lt;sup&gt;2&lt;/sup&gt;,&lt;sup&gt;*&lt;/sup&gt;, Faisal Fikri&lt;sup&gt;3&lt;/sup&gt;, Muhammad Thohawi Elziyad Purnama&lt;sup&gt;4&lt;/sup&gt;.&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;SubDivision of Veterinary Pharmacy, Division of Veterinary Basic Science, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Division of Veterinary Public Health, Department of Veterinary Science, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;SubDivision of Veterinary Pharmacology, Division of Veterinary Basic Science, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Division of Veterinary Anatomy, Department of Veterinary Science, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">T  Sudhakar Johnson</style></author><author><style face="normal" font="default" size="100%">D. B. Anantha Narayana</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Role of Spices in Offering Natural Immunity to Fight Various Diseases</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">COVID-19</style></keyword><keyword><style  face="normal" font="default" size="100%">Diet</style></keyword><keyword><style  face="normal" font="default" size="100%">Immunity</style></keyword><keyword><style  face="normal" font="default" size="100%">Nutrition</style></keyword><keyword><style  face="normal" font="default" size="100%">Spices</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2021</style></year><pub-dates><date><style  face="normal" font="default" size="100%">March 2021</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">13</style></volume><pages><style face="normal" font="default" size="100%">600-613</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;Adequate nutrition intake is one of main factors to strengthen immunity. Traditional and cultural practices of food consumption involve use of several spices in limited quantities as part of food. Spices have offered versatile biological effects due to presence of valuable biochemicals. The aim of the present paper is to review published scientific evidence on potential role of spices in offering innate and adaptive immunity to human body. It has been demonstrated that, turmeric, one of the widely used spices, acts as an anti-viral agent through inhibition of viral entry into cells, suppression of viral replication and modulation of cytokines. A field study revealed that nations with higher consumption of spices have shown lesser COVID-19 cases and higher recovery rates. Further, spices also have shown to possess antioxidant activity superior or equivalent to ascorbic acid and are known to regulate inflammation processes. Evidence generated from the published literature is compelling to arrive at a conclusion that consumption of spices might improve immunity there by offering protection against various diseases including COVID-19. It is also noted that there are lesser number of human clinical trials in this area which warrants immediate attention to provide scientific evidence to immunity offered by spices.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Review Article</style></work-type><section><style face="normal" font="default" size="100%">600</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;T. Sudhakar Johnson&lt;sup&gt;1&lt;/sup&gt;, D. B. Anantha Narayana&lt;sup&gt;2,&lt;/sup&gt;*&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Technical and Regulatory, Viridis Biopharma Pvt Ltd, Govandi, Mumbai-400 043, INDIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Chief Scientific Officer, Ayurvidye Trust, and Chairman, Scientific Panel, Nutraceuticals, Food Safety Standards Authority of India (FSSAI), Ministry of Health and Family Welfare, INDIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Jagadeep Chandra S</style></author><author><style face="normal" font="default" size="100%">Chandana GL</style></author><author><style face="normal" font="default" size="100%">Naganagouda V Kote</style></author><author><style face="normal" font="default" size="100%">Sharath Chandra SP</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Recent Scenario of Impact of Xenobiotics on Marine Fish: An Overview</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Fish</style></keyword><keyword><style  face="normal" font="default" size="100%">Litters</style></keyword><keyword><style  face="normal" font="default" size="100%">Marine</style></keyword><keyword><style  face="normal" font="default" size="100%">Xenobiotics</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">November 2020</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">12</style></volume><pages><style face="normal" font="default" size="100%">1797-1800</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;Xenobiotics from chemicals to plastics have seriously interfered with the biological process of living system. Their impact on aquatic ecosystem, fish in precise is studied with significant interest. However, studies on impact of xenobiotics on marine fish are limited. This literature review integrates and summarizes the impact of xenobiotics on marine fish. The review tries to understand the impact of macro and micro litters, microplastic, metals like mercury and nanoparticles. Finally, we conclude with the ways to regulate the presence and distribution of these xenobiotics in marine environment.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6s</style></issue><work-type><style face="normal" font="default" size="100%">Review Article</style></work-type><section><style face="normal" font="default" size="100%">1797</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Jagadeep Chandra S&lt;sup&gt;1&lt;/sup&gt;, Chandana GL&lt;sup&gt;2&lt;/sup&gt;, Naganagouda V Kote&lt;sup&gt;3&lt;/sup&gt;, Sharath Chandra SP&lt;sup&gt;4,&lt;/sup&gt;* &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Microbiology, Faculty of Life Sciences, JSS Academy of higher education and research, Mysuru, INDIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Biochemistry, Hassan Institute of Medical Sciences, Hassan, INDIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Biochemistry, Maharani`s Science College for Women, Bengaluru, INDIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Department of Biochemistry, Government Science College, Hassan, INDIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Bukinich Darya Dmitrievna</style></author><author><style face="normal" font="default" size="100%">Salova VG</style></author><author><style face="normal" font="default" size="100%">Odintsova EB</style></author><author><style face="normal" font="default" size="100%">Rastopchina OV</style></author><author><style face="normal" font="default" size="100%">Solovyovа NL</style></author><author><style face="normal" font="default" size="100%">Kozlova AM</style></author><author><style face="normal" font="default" size="100%">Krasniuk II (jun)</style></author><author><style face="normal" font="default" size="100%">Krasniuk II</style></author><author><style face="normal" font="default" size="100%">Kozlova Zh M</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Representatives of the Genus Goryanka (Epimedium L) – a Promising Source of Raw Materials for the Creation of Medicines for the Treatment of Erectile Dysfunction in Men</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Drug</style></keyword><keyword><style  face="normal" font="default" size="100%">Epimedium Estrellita</style></keyword><keyword><style  face="normal" font="default" size="100%">Icariin</style></keyword><keyword><style  face="normal" font="default" size="100%">Impotence</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">November 2020</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">12</style></volume><pages><style face="normal" font="default" size="100%">1710-1715</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;Erectile dysfunction and multiple mechanisms of its development are one of the most pressing problems of modern medicine. In the twenty-first century, millions of men around the world suffer from sexual disorders, and the number of such patients is only growing from year to year. The flavonoid icariin, contained in plants of the genus &lt;em&gt;Epimedium &lt;/em&gt;L., is a promising pharmacologically active substance used for erectile dysfunction, due to its ability to affect type 5 phosphodiesterase, inhibiting its activity. To date, domestic and foreign pharmaceutical companies produce biologically active food additives and herbal preparations, which include Goryanka extract. But the range of standardized herbal medicines is very small.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6s</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">1710</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Bukinich Darya Dmitrievna, Salova VG, Odintsova EB, Rastopchina OV, Solovyovа NL, Kozlova AM, Krasniuk II (jun), Krasniuk II, Kozlova Zh M* &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;First Moscow state medical university named after I.M. Sechenov, (Sechenov University), Moscow, RUSSIAN FEDERATION.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Nur Mursyida Saad</style></author><author><style face="normal" font="default" size="100%">Mahendran Sekar</style></author><author><style face="normal" font="default" size="100%">Siew Hua Gan</style></author><author><style face="normal" font="default" size="100%">Pei Teng Lum</style></author><author><style face="normal" font="default" size="100%">Jaishree Vaijanathappa</style></author><author><style face="normal" font="default" size="100%">Subban Ravi</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Resveratrol: Latest Scientific Evidences of its Chemical, Biological Activities and Therapeutic Potentials</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Bioavailability</style></keyword><keyword><style  face="normal" font="default" size="100%">Inflammatory cytokines</style></keyword><keyword><style  face="normal" font="default" size="100%">Molecular targets</style></keyword><keyword><style  face="normal" font="default" size="100%">Pharmacology</style></keyword><keyword><style  face="normal" font="default" size="100%">Resveratrol</style></keyword><keyword><style  face="normal" font="default" size="100%">Toxicity</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">November 2020</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">12</style></volume><pages><style face="normal" font="default" size="100%">1779-1791</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; Resveratrol is a non-flavonoid polyphenol possesses many biological properties with great potential to develop into various products. In order to cure a wide variety of diseases, resveratrol has attracted a great deal of attention for medicinal purposes.&lt;strong&gt; Objective:&lt;/strong&gt; The present review aimed to provide a comprehensive literature summary of latest scientific evidences on the chemistry, biological properties and therapeutic potentials of resveratrol. &lt;strong&gt;Methods: &lt;/strong&gt;To complete this review, relevant literatures were collected from several scientific databases, including Google Scholar, Pubmed and ScienceDirect, using keywords “source”, “chemistry”, “bioavailability”, “pharmacokinetics”, “isolation”, “anticancer”, “analgesic”, “antiinflammatory”, “antidiabetic”, “nephroprotective activity”, “neuroprotective activity”, “antiobesity”, “cardioprotective effects”, “antioxidant”, “anti-aging” with resveratrol. After a detailed screening process for inclusion and exclusion, the information obtained was summarised.&lt;strong&gt; Results:&lt;/strong&gt; The information on the source, chemistry, bioavailability, biological and therapeutic potentials of resveratrol were tabled. In various pathological conditions, resveratrol can be considered as powerful antioxidants along with multidimensional molecular targets such as NF-ҡB, MAPK, AMPK, SIRT-1, Nrf-2, m-TOR, PI3K/Akt and PPAR-γ signaling pathways. &lt;strong&gt;Conclusion:&lt;/strong&gt; Based on the existing knowledge, we may believe that resveratrol has a significant therapeutic potential for the treatment of various diseases. To accelerate the development and utilization of resveratrol as promising products, in-depth studies should be focused on exploiting its properties and developing phytopharmaceuticals.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6s</style></issue><work-type><style face="normal" font="default" size="100%">Review Article</style></work-type><section><style face="normal" font="default" size="100%">1779</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Nur Mursyida Saad&lt;sup&gt;1&lt;/sup&gt;, Mahendran Sekar&lt;sup&gt;1,&lt;/sup&gt;*, Siew Hua Gan&lt;sup&gt;2&lt;/sup&gt;, Pei Teng Lum&lt;sup&gt;1&lt;/sup&gt;, Jaishree Vaijanathappa&lt;sup&gt;3&lt;/sup&gt;, Subban Ravi&lt;sup&gt;4 &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmaceutical Chemistry, Faculty of Pharmacy and Health Sciences, Universiti Kuala Lumpur Royal College of Medicine Perak, Ipoh – 30450, Perak, MALAYSIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;School of Pharmacy, Monash University Malaysia, Bandar Sunway 47500, Selangor Darul Ehsan, MALAYSIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Pharmaceutical Chemistry, JSS College of Pharmacy, Mysuru – 570015, JSS Academy of Higher Education and Research, Mysuru, Karnataka, INDIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Department of Chemistry, Karpagam Academy of Higher Education, Coimbatore – 640 021, Tamil Nadu, INDIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Gunawan Pasaribu</style></author><author><style face="normal" font="default" size="100%">Emil Budianto</style></author><author><style face="normal" font="default" size="100%">Herry Cahyana</style></author><author><style face="normal" font="default" size="100%">Endang Saepudin</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">A Review on Genus Saurauia: Chemical Compounds and their Biological Activity</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Biological activity</style></keyword><keyword><style  face="normal" font="default" size="100%">Chemical compounds</style></keyword><keyword><style  face="normal" font="default" size="100%">Human disease remedy</style></keyword><keyword><style  face="normal" font="default" size="100%">Saurauia</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">May 2020</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">12</style></volume><pages><style face="normal" font="default" size="100%">657-666</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;&lt;em&gt;Saurauia&lt;/em&gt; plant has been widely used to treat a variety of diseases suffered by villagers at various places in the world. These species are widely used traditionally by the community as antidiabetic and digestive problems’ remedy. This paper will present various uses and researches ever carried out by researchers in the world on various types of the genus &lt;em&gt;Saurauia&lt;/em&gt;.&lt;strong&gt; Methods:&lt;/strong&gt; The Information was collected from scientific journals, books, and reports.&lt;strong&gt; Results: &lt;/strong&gt;This review summarizes the existing information on several species of&lt;em&gt; Saurauia&lt;/em&gt; in relation to their chemical compounds and biological activity. There are some of chemical compounds present and identified in &lt;em&gt;Saurauia&lt;/em&gt;, i.e. 3β-hydroxy-Olean-12-en- 28oic acid; 3,19-Dihydroxyurs-12-en-28-oic acid; 3-hidroksi, 12(13)-en, 28-oleanolat acid; actinidin; several monoterpene lactones; seven triterpenoids, namely, cis-3-O-p-hydroxycinnamoyl ursolic acid; trans-3-O-p-hydroxycinnamoyl ursolic acid; ursolic acid; oleanolic acid; corosolic acid; maslinic acid; and β-amyrin; and two steroids, stigmasterol; and β-sitosterol. There are several biological activities afforded by &lt;em&gt;Saurauia &lt;/em&gt;i.e. antioxidant activity, anti-cholesterol, antidiabetic activity, antihyperlipidemic, analgetic activity, antimicrobial activity, wound-healing activity and immunostimulatory activity.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Review Article</style></work-type><section><style face="normal" font="default" size="100%">657</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Gunawan Pasaribu&lt;sup&gt;1,&lt;/sup&gt;*, Emil Budianto&lt;sup&gt;2&lt;/sup&gt;, Herry Cahyana&lt;sup&gt;2&lt;/sup&gt;, Endang Saepudin&lt;sup&gt;2 &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;1&lt;/sup&gt;Postgraduated Student at Department of Chemistry, Faculty of Matematics and Natural Sciences, Universitas Indonesia, Depok, INDONESIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Chemistry, Faculty of Matematics and Natural Sciences, Universitas Indonesia, Depok, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">M Devi</style></author><author><style face="normal" font="default" size="100%">S Dhanalakshmi</style></author><author><style face="normal" font="default" size="100%">GE Thillai Govindarajan</style></author><author><style face="normal" font="default" size="100%">BA Tanisha</style></author><author><style face="normal" font="default" size="100%">Talluri Sonalika</style></author><author><style face="normal" font="default" size="100%">JE Ruth</style></author><author><style face="normal" font="default" size="100%">T Avinash</style></author><author><style face="normal" font="default" size="100%">C Jethendra Sri</style></author><author><style face="normal" font="default" size="100%">K Logeswaran</style></author><author><style face="normal" font="default" size="100%">M Nithish Ramasamy</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">A Review on Phaseolus vulgaris Linn</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Food crop</style></keyword><keyword><style  face="normal" font="default" size="100%">Obesity</style></keyword><keyword><style  face="normal" font="default" size="100%">Phaseolus vulgaris Linn</style></keyword><keyword><style  face="normal" font="default" size="100%">Urolithiasis</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">August 2020</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">12</style></volume><pages><style face="normal" font="default" size="100%">1160-1164</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;Medicinal herbs have been discovered and used in traditional medicine practices since antiquated times. &lt;em&gt;Phaseolus vulgaris&lt;/em&gt; Linn. (Family-Fabaceae) commonly known as French bean, is a most consuming carbohydrate and protein rich food crop having medicinal values. This plant having diverse compounds like carbohydrate, proteins, flavonoids, Saponins, tannins and phenolic acid. The seeds of&lt;em&gt; Phaseolus vulgaris &lt;/em&gt;Linn. Possess having anti-urolithiatic activity and anti- obesity activity. This review provides a summary of phytochemistry and pharmacological effect of &lt;em&gt;Phaseolus vulgaris &lt;/em&gt;Linn., The plant can be further investigated for other pharmacological activities as it contains variety of chemical constituents and it is a commonly using food crop and medical remedies of this plant are sync with nature.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Review Article</style></work-type><section><style face="normal" font="default" size="100%">1160</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;M Devi&lt;sup&gt;1&lt;/sup&gt;,*, S Dhanalakshmi&lt;sup&gt;2&lt;/sup&gt;, GE Thillai Govindarajan&lt;sup&gt;3&lt;/sup&gt;, BA Tanisha&lt;sup&gt;3&lt;/sup&gt;, Talluri Sonalika&lt;sup&gt;3&lt;/sup&gt;, JE Ruth&lt;sup&gt;3&lt;/sup&gt;, T Avinash&lt;sup&gt;3&lt;/sup&gt;, C Jethendra Sri&lt;sup&gt;3&lt;/sup&gt;, K Logeswaran&lt;sup&gt;3&lt;/sup&gt;, M Nithish Ramasamy&lt;sup&gt;3&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmacology, Faculty of Pharmacy, Dr. M.G.R. Educational and Research Institute, Velappanchavadi 600 077, Chennai, INDIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Pharmacognosy, Faculty of Pharmacy, Dr. M.G.R. Educational and Research Institute, Velappanchavadi 600 077, Chennai, INDIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Pharma Buddy, Faculty of Pharmacy, Dr. M.G.R. Educational and Research Institute, Velappanchavadi 600 077, Chennai, INDIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Shikha Dixit</style></author><author><style face="normal" font="default" size="100%">Sugandha Tiwari</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Review on Plants for Management of Diabetes in India: An Ethno- Botanical and Pharmacological Perspective</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Diabetes management</style></keyword><keyword><style  face="normal" font="default" size="100%">Ethnopharmacology</style></keyword><keyword><style  face="normal" font="default" size="100%">Herbal drugs</style></keyword><keyword><style  face="normal" font="default" size="100%">India</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">November 2020</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">12</style></volume><pages><style face="normal" font="default" size="100%">1801-1810</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background: &lt;/strong&gt;Diabetes mellitus is a prevalent chronic disease, which is recognized as a common threat to health in the last decade, especially in Asia. It is a lifestyle disease which may cause a number of complications in the body of humans like cardiac failure and dysfunctioning of urinary tract. &lt;strong&gt;Materials and Methods:&lt;/strong&gt; The data is obtained from various search tools and electronic databases like, scientific literature, Google scholar, Google, Pubmed, Web of science and Scopus. &lt;strong&gt;Results: &lt;/strong&gt;Major therapy for diabetes is insulin, oralantidiabetic drugs, and herbal treatment. However, insulin and oral anti-diabetic drugs come with a number of side effects and cannot be afforded by people with below poverty line. The herbal medicines have performed a satisfactory clinical practice for the management of diabetes mellitus. Moreover, pharmacological &amp;amp; phytochemical screening of medicinal plants has also witnessed the hypoglycaemic effects of these plants in treating diabetes mellitus. Majority of the modern drugs like metformin, atropine, digitalis, etc. are also originated from plants. &lt;strong&gt;Conclusion: &lt;/strong&gt;The current paper presents a review of medicinal plants used for diabetes management in India. The therapeutic potential, ethnobotanical use, and their pharmacological evaluations are highlighted for harnessing the anti-diabetic potential of these plants by the Indian healthcare system.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6s</style></issue><work-type><style face="normal" font="default" size="100%">Review Article</style></work-type><section><style face="normal" font="default" size="100%">1801</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Shikha Dixit*, Sugandha Tiwari &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;Department of Botany, DGPG College, CSJMU Kanpur, INDIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">S Swarna Meenakshi</style></author><author><style face="normal" font="default" size="100%">Sheeja S Varghese</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">The Role of Recombinant Parathormone derivative in Bone healing. Making the Unfavorable, Favorable - A Systematic Review</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Bone healing</style></keyword><keyword><style  face="normal" font="default" size="100%">Fracture</style></keyword><keyword><style  face="normal" font="default" size="100%">Parathormone</style></keyword><keyword><style  face="normal" font="default" size="100%">Recombinant derivative</style></keyword><keyword><style  face="normal" font="default" size="100%">Teriparatide</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">November 2020</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">12</style></volume><pages><style face="normal" font="default" size="100%">1753-1768</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background: &lt;/strong&gt;Teriparatide is a recombinant parathormone derivative encompassing the first 1-34 amino acids off PTH, which is said to contain potent anabolic capability. It is said to induce osteoblastogenesis thereby placing an essential role in bone healing. The aim of this systematic review is to evaluate the best available evidence from randomized controlled trials analyzing the effectiveness of teriparatide on bone regeneration and healing in osteoporotic patients and patients with fractures. &lt;strong&gt;Aim:&lt;/strong&gt; This systematic review aims to assess whether Teriparatide enhances bone regeneration and healing in terms of improving clinical, radiographic, histologic parameters and Biomarkers of Bone formation and resorption. &lt;strong&gt;Materials and Methodology:&lt;/strong&gt; A comprehensive search was done in databases such as ‘PubMed’, ‘Google Scholar and ‘Cochrane’ databases based on pre-determined eligibility criteria. Randomized control trials assessing the effectiveness of Teriparatide in Bone healing in fractures as well as osteoporosis were selected after thorough screening.&lt;strong&gt; Results: &lt;/strong&gt;The selected 13 studies compared teriparatide to either placebo or another anti-resorptive drug. Out of the 13, 8 studies were done to evaluate the improvement and healing of bone in Osteoporotic patients whereas 5 studies were done on improvement in fracture healing. The studies evaluated outcome parameters such as Clinical and Radiological improvement, Biomarkers of Bone resorption and formation and Safety.6 studies assessed clinical parameters, 12 studies assessed radiological parameters, 7 studies assessed biomarkers, 11 studies assessed safety parameters by means of occurrence of any adverse effects. All the 8 studies done on osteoporotic patients showed a good improvement. Of the 5 studies on fracture healing, only 2 studies showed beneficial effects while the other 3 did not show any benefits. &lt;strong&gt;Conclusion:&lt;/strong&gt; Teriparatide could have beneficial effects in bone healing in osteoporotic patients and is well tolerated. However, the results are inconclusive whether they have beneficial effects in treating fractures. More Homogenous Randomized control trials are required to ascertain whether teriparatide could improve bone healing.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6s</style></issue><work-type><style face="normal" font="default" size="100%">Review Article</style></work-type><section><style face="normal" font="default" size="100%">1753</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;S Swarna Meenakshi&lt;sup&gt;1,&lt;/sup&gt;*, Sheeja S Varghese&lt;sup&gt;2&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Post Graduate student, Department of Periodontics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University,Chennai, INDIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Professor, Department of Periodontics, Dean of Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, INDIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Olga Trifonova</style></author><author><style face="normal" font="default" size="100%">Olga Evdokimova</style></author><author><style face="normal" font="default" size="100%">Vera Prokofieva</style></author><author><style face="normal" font="default" size="100%">Alexey Matyushin</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Rationale for Manufacturing of Cut-Pressed Granules from Herbal Raw Material Rich in Essential Oil: An Example of Chamomile Flowers and Sweet Flag Rhizome</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Chamomile</style></keyword><keyword><style  face="normal" font="default" size="100%">Cut-pressed granules</style></keyword><keyword><style  face="normal" font="default" size="100%">Dosage form</style></keyword><keyword><style  face="normal" font="default" size="100%">Essential oil</style></keyword><keyword><style  face="normal" font="default" size="100%">Herbal drugs</style></keyword><keyword><style  face="normal" font="default" size="100%">Sweet flag</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">October 2019</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">11</style></volume><pages><style face="normal" font="default" size="100%">1285-1289</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background: &lt;/strong&gt;Currently, there are at least 43 different dosage forms present on the Russian Federation pharmaceutical market. A novel, unique dosage form – cut-pressed granules (CPG) – was developed in order to improve manufacturing characteristics and, therefore, quality of herbal drug products released in tea bags. However, treatment conditions may result in decreased levels of active substances in some of the plants, especially those containing essential oil, which is prone to degradation. The aim of this study was to assess feasibility of CPG manufacturing from herbal raw material rich in essential oil. &lt;strong&gt;Materials and Methods: &lt;/strong&gt;Different morphological groups of raw material from two commonly used medicinal plants, chamomile (&lt;em&gt;Matricaria recutita&lt;/em&gt; L.) flowers and sweet flag (&lt;em&gt;Acorus calamus&lt;/em&gt; L.) rhizome, were chosen as the objects of the study. Qualitative composition of lipophilic constituents in herbal raw materials and CPG was assessed using thin-layer chromatography. Essential oil content was determined by steam distillation.&lt;strong&gt; Results:&lt;/strong&gt; The results confirmed equivalence of chromatographic profiles for the analyzed raw materials and CPG; thus, granulation didn’t affect qualitative composition of lipophilic components in chamomile flowers and sweet flag rhizome. The study also showed that the granulation process, in fact, promoted stability of the dosage form: during long-term storage the content of essential oil in all of the assessed cut-pressed granules was equivalent or higher than in corresponding herbal raw material. &lt;strong&gt;Conclusions:&lt;/strong&gt; It can be concluded that &lt;em&gt;Matricaria recutita &lt;/em&gt;L. flowers and &lt;em&gt;Acorus calamus&lt;/em&gt; L. rhizome can be used as herbal raw material for CPG manufacturing.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">1285</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Olga Trifonova&lt;sup&gt;1,2&lt;/sup&gt;, Olga Evdokimova&lt;sup&gt;3&lt;/sup&gt;, Vera Prokofieva&lt;sup&gt;4&lt;/sup&gt;, Alexey Matyushin&lt;sup&gt;5&lt;/sup&gt;,* &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmacy, Sechenov First Moscow State Medical University, Moscow, RUSSIAN FEDERATION.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;JSC “Krasnogorskleksredstva”, Krasnogorsk, RUSSIAN FEDERATION.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Federal State Budgetary Institution Scientific Centre for Expert Evaluation of Medicinal Products of the Ministry of Health of the Russian Federation, Moscow, RUSSIAN FEDERATION.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;A.P. Arzamastsev Department of Pharmaceutical and Toxicological Chemistry, Sechenov First Moscow State Medical University, Moscow, RUSSIAN FEDERATION.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;5&lt;/sup&gt;Department of Analytical and Forensic Toxicology, Sechenov First Moscow State Medical University, Moscow, RUSSIAN FEDERATION.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Sasithorn Tandhavadhana</style></author><author><style face="normal" font="default" size="100%">Chayan Picheansoonthon</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Reduction of Colchicine Content from Radix Gloriosae Superbae Preparata</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Colchicine</style></keyword><keyword><style  face="normal" font="default" size="100%">Gloriosae Superbae Radix</style></keyword><keyword><style  face="normal" font="default" size="100%">HPLC</style></keyword><keyword><style  face="normal" font="default" size="100%">Pre-treat method</style></keyword><keyword><style  face="normal" font="default" size="100%">Thai herbal remedy</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">February 2019</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">11</style></volume><pages><style face="normal" font="default" size="100%">310-314</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; Gloriosae Superbae Radix is a crude drug employed in Thai herbal remedies for several ailments. Colchicine is known as an active constituent in the roots. It was reported that 7-11 mg. of colchicine may causes lethal effect in human. In Thai traditional medical practice, the roots must be treated prior use to prepare Thai herbal preparations. However, pre-treated method has not yet been well established in any literature. This study aimed to document the pre-treated method and to quantitatively compare the amount of colchicine both before and after pre-treated. &lt;strong&gt;Methods:&lt;/strong&gt; Firstly, interviewing with Thai traditional medicine experts and document the pre-treated methods of Gloriosae Superbae Radix to conclude the 2 commonly used methods. Two pre-treated methods (roasting and burning) were chosen for further study. Colchicine in Gloriosae Superbae Radix from 8 sources were analyzed before and after pre-treat by High Performance Liquid Chromatography (HPLC). &lt;strong&gt;Results:&lt;/strong&gt; After pre-treat by roasting and burning, amount of colchicine in root were significantly decreased by 40.61±9.55% (&lt;em&gt;p&lt;/em&gt;=0.000) and 26.79±10.89% (&lt;em&gt;p&lt;/em&gt;=0.001), respectively. Comparison of colchicine contents of samples after roasting and burning, the amount of colchicine decreased non statistically insignificantly (&lt;em&gt;p&lt;/em&gt;=0.110). &lt;strong&gt;Conclusion:&lt;/strong&gt; Pre-treats of Gloriosae Superbae Radix by roasting and burning had significantly reduce colchicine content. Both methods have been proven to be the effective ways in preparing certain potentially toxic crude drugs before using in compounding into Thai herbal remedies.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">310</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Sasithorn Tandhavadhana, Chayan Picheansoonthon&lt;sup&gt;*&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p&gt;Faculty of Medicine, Mahasarakham University, THAILAND.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Yori Yuliandra</style></author><author><style face="normal" font="default" size="100%">Armenia Armenia</style></author><author><style face="normal" font="default" size="100%">Rahmad Arief</style></author><author><style face="normal" font="default" size="100%">Mifta Hul Jannah</style></author><author><style face="normal" font="default" size="100%">Helmi Arifin</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Reversible Hepatotoxicity of Cassytha filiformis Extract: Experimental Study on Liver Function and Propofol-Induced Sleep in Mice</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Cassytha filiformis</style></keyword><keyword><style  face="normal" font="default" size="100%">Liver function</style></keyword><keyword><style  face="normal" font="default" size="100%">Propofol</style></keyword><keyword><style  face="normal" font="default" size="100%">Reversible toxicity</style></keyword><keyword><style  face="normal" font="default" size="100%">Sleep time</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">January 2019</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">11</style></volume><pages><style face="normal" font="default" size="100%">69-74</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Objective:&lt;/strong&gt; To study the liver toxicity of &lt;em&gt;Cassytha filiformis&lt;/em&gt; L. extract and its reversibility in mice. &lt;strong&gt;Methods:&lt;/strong&gt; A total of 108 male mice were used to investigate the hepatotoxicity of &lt;em&gt;Cassytha filiformis&lt;/em&gt; extract (CFE) and the reversibility of its toxicity to the liver. Seventy-two mice were treated with CFE orally for 7 consecutive days. A half of these animals were used to study the sleep time on propofol-induced sleep that comprised the sleep onset time (SOT) and duration of sleep (DOS), while another half was used for the quantitation of serum alanine transaminase (ALT) activity. To investigate the reversibility of the liver toxicity, thirty-six mice were treated with daily CFE for 7 days. Activities of ALT and alkaline phosphatase (ALP) were determined and the liver weight ratio was measured on day 0, 1, 3 and 7 after the termination of the CFE treatment. Data of liver toxicity determination were analyzed by two-way ANOVA followed by Duncan’s multiple range test, while data of the reversibility was analyzed by Pearson’s correlation. The significance level was taken at 95% of confidence interval.&lt;strong&gt; Results:&lt;/strong&gt; CFE shortened the SOT and prolonged the DOS significantly compared with control (&lt;em&gt;p&lt;/em&gt;&amp;lt;0.05). The activity of ALT was increased due to the toxicity of CFE. However, the ALT/ALP activities decreased and liver weight ratio increased gradually after the extract treatment was discontinued. The trend of these data was correlated significantly (&lt;em&gt;p&lt;/em&gt;&amp;lt;0.05). &lt;strong&gt;Conclusion:&lt;/strong&gt; &lt;em&gt;Cassytha filiformis&lt;/em&gt; L. extract is toxic to the liver but the toxicity is reversible depending on doses.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">69</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Yori Yuliandra, Armenia Armenia*, Rahmad Arief, Mifta Hul Jannah, Helmi Arifin &lt;/strong&gt;&lt;/p&gt;

&lt;p&gt;Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Andalas University, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Rima Boukhary</style></author><author><style face="normal" font="default" size="100%">Maha Aboul-Ela</style></author><author><style face="normal" font="default" size="100%">Abdalla El-Lakany</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Review on Chemical Constituents and Biological Activities of Genus Anthemis</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Anthemis</style></keyword><keyword><style  face="normal" font="default" size="100%">Anti-inflammatory</style></keyword><keyword><style  face="normal" font="default" size="100%">Anti-oxidant</style></keyword><keyword><style  face="normal" font="default" size="100%">Flavonoids</style></keyword><keyword><style  face="normal" font="default" size="100%">Sesquiterpenes</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">September 2019</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">11</style></volume><pages><style face="normal" font="default" size="100%">1155-1166</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;Genus &lt;em&gt;Anthemis&lt;/em&gt; of Family Asteraceae contains mainly flavonoids, sesquiterpene lactones belonging to germacranolides, eudesmanolides, guaianolides, sterols and essential oils. The Plants of genus Anthemis have been known to have anti-inflammatory, hepatoprotective and antioxidant activities due to their rich contents of important physiological and biological compounds. They are referred to as nature’s biological response modifier’s and are involved in energy transfer, photosensitization and morphogenesis. Several clinical studies have shown that people who take diets rich in flavonoids and sesquiterpenes have reduced risk of developing cancer and cardiovascular diseases. This article covers most of constituents of plants of genus Anthemis reported from 2002 up to 2018. Furthermore, the biological activities of plants of genus Anthemis will be presented.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Review Article</style></work-type><section><style face="normal" font="default" size="100%">1155</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Rima Boukhary*, Maha Aboul- ElA, Abdalla El-Lakany&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;Department of Pharmaceutical Sciences, Faculty of Pharmacy, Beirut Arab University, 115020 Beirut, LEBANON.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Dwaipayan Sinha</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">A Review on Ethnobotanical, Phytochemical and Pharmacological Profile of Pinus wallichiana A.B. Jacks</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antioxidant</style></keyword><keyword><style  face="normal" font="default" size="100%">Arthritis</style></keyword><keyword><style  face="normal" font="default" size="100%">Conifer</style></keyword><keyword><style  face="normal" font="default" size="100%">Flavonoids</style></keyword><keyword><style  face="normal" font="default" size="100%">Himalaya</style></keyword><keyword><style  face="normal" font="default" size="100%">Terpenoids</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">July 2019</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">11</style></volume><pages><style face="normal" font="default" size="100%">624-631</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; &lt;em&gt;Pinus wallichiana &lt;/em&gt;A.B. Jacks. or the blue pine is one of the important conifer that grows all along the Himalayan range from Afghanistan in the west to Myanmar and China in the east covering the Himalayan regions of Pakistan, Nepal and India. It is found in the upper region of the mountains and often remains associated with other gymnosperms. The plant is of immense ethnobotanical relevance and finds extensive use among the people inhabiting the mountainous region. They are primarily valued for its timber and used for construction and infrastructural purposes. Medicinally the plant is very much important. Throughout the Himalayan region the plant is used for the cure of a number of diseases including treatment of fever, cough and cold, bone fracture, healing of injury and wounds, rheumatic pain, arthritis, inflammations etc. The plant is rich in terpenoids and flavonoids all of which possess strong antioxidant properties. &lt;strong&gt;Methods: &lt;/strong&gt;Extensive literature survey was made in the internet with pubmed, google scholar forming the search platform to illustrate the traditional usage of the plant among inhabitants of various regions of Himalayas. Informations of traditional usage, chemical constituents and selected pharmacological activities of the plant were pooled from available research papers to frame the review. &lt;strong&gt;Results and Outcome:&lt;/strong&gt; In this review, an attempt has been made to compile the ethnobotanical usage of &lt;em&gt;Pinus wallichiana&lt;/em&gt;, its phytochemistry and pharmacological activity highlighting its potentiality as a cheap and affordable source of drugs for the benefit of population of Indian subcontinent and adjoining areas.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Review Article</style></work-type><section><style face="normal" font="default" size="100%">624</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Dwaipayan Sinha* &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;Department of Botany, Government General Degree College, Mohanpur, Paschim Medinipur West Bengal-721436, INDIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Noha A Khalil</style></author><author><style face="normal" font="default" size="100%">Amira Abdel Motaal</style></author><author><style face="normal" font="default" size="100%">Khaled Meselhy</style></author><author><style face="normal" font="default" size="100%">Soad M Abdel khalek</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Renin and Angiotensin Converting Enzyme Inhibition of Standardized Bioactive Fractions of Hyphaene thebaica L. Mart Growing in Egypt</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antihypertensive</style></keyword><keyword><style  face="normal" font="default" size="100%">Doum</style></keyword><keyword><style  face="normal" font="default" size="100%">HPLC</style></keyword><keyword><style  face="normal" font="default" size="100%">Phenolics</style></keyword><keyword><style  face="normal" font="default" size="100%">standardization</style></keyword><keyword><style  face="normal" font="default" size="100%">Validation</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">June 2018</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://fulltxt.org/article/640</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">10</style></volume><pages><style face="normal" font="default" size="100%">622-627</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; &lt;em&gt;Hyphaene thebaica&lt;/em&gt; L. fruit is known in Egypt for its antihypertensive activity. However a standardized herbal extract/fraction was never prepared.&lt;strong&gt; Methods:&lt;/strong&gt; A biologically guided fractionation was carried out &lt;em&gt;in-vitro&lt;/em&gt; for the 50% and 70% ethanol extracts of &lt;em&gt;Hyphaene thebaica&lt;/em&gt; L. fruit using the angiotensin converting enzyme (ACE) inhibition and renin inhibition assays. A validated reversed phase HPLC method was developed for the standardization of the active fractions. Results: The ethyl acetate fraction of the 70% extract contained higher percentages of the three bioactive markers chlorogenic acid, quercetin and apigenin (1.940 &amp;plusmn; 0.140%, 2.994 &amp;plusmn; 0.349% and 0.612 &amp;plusmn; 0.0354%, respectively) relative to the ethyl acetate fraction of the 50% extract (1.384 &amp;plusmn; 0.157%, 0.342 &amp;plusmn; 0.0834% and 0.070 &amp;plusmn; 0.00225%, respectively). The butanol fraction of the 70% extract was found to possess the highest antihypertensive activity (93.69 &amp;plusmn; 5.695 % renin inhibition activity at 0.5 mg/mL and IC&lt;sub&gt;50&lt;/sub&gt; of 0.001436 +0.00044 mg/mL for ACE inhibition activity). A standard calibration curve for the three compounds was established at a concentration range of 0.1-50 &amp;mu;g/Ml, they showed good linearity with a correlation coefficient (R&lt;sup&gt;2&lt;/sup&gt;) of (1.00, 1.00 and 0.999; respectively). A high degree of precision (relative standard deviation values &amp;lt;5%) was achieved. The limits of detection for the three compounds were 0.428, 0.368 and 0.849; respectively, while the limits of quantitation were 1.29, 1.11 and 2.57, respectively. &lt;strong&gt;Conclusions:&lt;/strong&gt; Current results showed that the butanol fraction of the 70% extract revealed the highest antihypertensive activity through ACE and renin inhibition mechanisms. In addition, recorded observations concerning linearity of the used bioactive markers offer a support for the possible utility of the tested fractions as potent standardized antihypertensive drugs.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">622</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Noha A Khalil&lt;sup&gt;1*&lt;/sup&gt;, Amira Abdel Motaal&lt;sup&gt;2,3&lt;/sup&gt;, K M Meselhy&lt;sup&gt;3&lt;/sup&gt;, Soad M Abdel Khalek&lt;/strong&gt;&lt;sup&gt;&lt;strong&gt;4&lt;/strong&gt; &lt;/sup&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmacognosy, Faculty of Pharmacy, Misr International University, EGYPT.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Pharmacognosy, College of Pharmacy, King Khaled University, Abha, KINGDOM OF SAUDI ARABIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Pharmacognosy, Faculty of Pharmacy, Cairo University, EGYPT.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Department of Pharmacognosy, Faculty of Pharmacy, Nahda University, BeniSuef, Helwan University, EGYPT.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Niken Indriyanti</style></author><author><style face="normal" font="default" size="100%">Afrillia Nuryanti Garmana</style></author><author><style face="normal" font="default" size="100%">Finna Setiawan</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Repairing Effects of Aqueous Extract of Kalanchoe pinnata (Lmk) Pers. on Lupus Nephritis Mice</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Docking</style></keyword><keyword><style  face="normal" font="default" size="100%">Glomerulonephritis</style></keyword><keyword><style  face="normal" font="default" size="100%">Inflammation</style></keyword><keyword><style  face="normal" font="default" size="100%">Lupus</style></keyword><keyword><style  face="normal" font="default" size="100%">Proteinuria</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">March 2018</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://fulltxt.org/article/522</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">10</style></volume><pages><style face="normal" font="default" size="100%">548-552</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;em&gt;Kalanchoe pinnata&lt;/em&gt; (Lmk) Pers (KP) has an immunosuppressive effect on delayed-type hypersensitivity test. Based on it, this research aimed to determine the repairing effects of aqueous extract of KP on lupus nephritis mice and identified its active compound. The KP extract profile was determined using UPLC-QTOF-MS/MS instrument. We examined six mice groups consisting of three curative treatment groups, one standard group receiving prednisone, one preventive group receiving KP extract, and one healthy (healthy and untreated) group. At the end of the experiment, we measured the proteinuria and renal histology parameters. To recognize the active compound in the KP profile, we performed &lt;em&gt;in silico&lt;/em&gt; assays for the flavonoid compounds to bind to the glucocorticoid receptor. We played &lt;em&gt;in silico&lt;/em&gt; tests for the flavonoid compounds to identify the active compound in the KP profile. We found the repairing effect of KP was detected in the kidney, demonstrated by its low proteinuria level and its better tissue structure. In the curative group, the urine protein level and its glomerular inflammation decreased. In the preventive group, the aqueous extract of KP could prevent lupus nephritis manifestations in the kidney. Bryophyllin A is the most active compound of the KP. However, further research is needed to understand the mechanism involved. We conclude, the aqueous extract, especially its bryophyllin A, have beneficial effects in repairing the function and tissue structure of lupus manifestations in mice kidney.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">548</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Niken Indriyanti&lt;sup&gt;1*&lt;/sup&gt;, Afrillia Nuryanti Garmana&lt;sup&gt;2&lt;/sup&gt;, Finna Setiawan&lt;sup&gt;3&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmacology, Faculty of Pharmacy, Mulawarman University, East Kalimantan, INDONESIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Pharmacology and Clinical Pharmacy, School of Pharmacy, Bandung Institute of Technology, West Java, INDONESIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Pharmaceutical Biology, Faculty of Pharmacy, Universitas Surabaya, East Java, INDONESIA.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Shanmugam Vinodhini</style></author><author><style face="normal" font="default" size="100%">Devi Rajeswari V</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Review on Ethnomedical Uses, Pharmacological Activity and Phytochemical Constituents of Samanea Saman(jacq.) Merr. Rain Tree</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Chemical constituents</style></keyword><keyword><style  face="normal" font="default" size="100%">Gas production</style></keyword><keyword><style  face="normal" font="default" size="100%">Nanoparticles</style></keyword><keyword><style  face="normal" font="default" size="100%">Pharmacological activities</style></keyword><keyword><style  face="normal" font="default" size="100%">Samanea saman</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">January 2018</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://fulltxt.org/article/465</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">10</style></volume><pages><style face="normal" font="default" size="100%">202-209</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;Medicinal plants have been used as therapeutic drug throughout the world. But, a very few of them have been scientifically validated. &lt;em&gt;Samanea Saman&lt;/em&gt; belongs to the&lt;em&gt; Leguminosae&lt;/em&gt; family commonly known as rain tree and is native to tropical America. &lt;em&gt;S.saman&lt;/em&gt; tree has different parts like a leaf, fruits, pods, seeds, and wood. &lt;em&gt;S.saman &lt;/em&gt;is currently studied for the production of biogas which is easily obtained in the urban and rural areas.&lt;em&gt; S.saman&lt;/em&gt; has been used in traditional medicine as a remedy for the treatment of different diseases. The phytochemical screening of the plant revealed the presence of alkaloids&amp;ndash;C&lt;sub&gt;8&lt;/sub&gt;H&lt;sub&gt;17&lt;/sub&gt;ON and C&lt;sub&gt;17&lt;/sub&gt;H&lt;sub&gt;36&lt;/sub&gt;ON&lt;sub&gt;3&lt;/sub&gt; pithecolobine and saponin (samarin). Natural products are mainly derived from medicinal plants, which are tested &lt;em&gt;in vitro&lt;/em&gt; and &lt;em&gt;in vivo&lt;/em&gt; models and used to investigate the mechanism of action of drugs with potential biological properties. Additionally, &lt;em&gt;S.saman&lt;/em&gt; were recommended as the suitable tree for planting in the urban environment as this species can reduce the outdoor temperature for all types of ground covers. This review is mainly focused on antioxidant, antibacterial, anti-diabetic potential, insecticidal, antifungal, analgesic, anti-ulcer and cytotoxic activities. However, this study helps to develop new strategies for the designing of novel drugs to treat various diseases related to human race.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Review Article</style></work-type><section><style face="normal" font="default" size="100%">202</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Shanmugam Vinodhini, Devi Rajeswari V* &lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;Department of Biomedical Sciences, School of Biosciences and Technology, VIT University, Vellore, Tamil Nadu, INDIA.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Aditi Sharma</style></author><author><style face="normal" font="default" size="100%">Lalit Sharma</style></author><author><style face="normal" font="default" size="100%">Rohit Goyal</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">A Review on Himalayan Pine Species: Ethnopharmacological, Phytochemical and Pharmacological Aspects</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Ethanopharmacology</style></keyword><keyword><style  face="normal" font="default" size="100%">Himalayas</style></keyword><keyword><style  face="normal" font="default" size="100%">Pharmacology</style></keyword><keyword><style  face="normal" font="default" size="100%">Phytochemistry</style></keyword><keyword><style  face="normal" font="default" size="100%">Pinus</style></keyword><keyword><style  face="normal" font="default" size="100%">Pinus gerardiana</style></keyword><keyword><style  face="normal" font="default" size="100%">Pinus roxburghii</style></keyword><keyword><style  face="normal" font="default" size="100%">Pinus wallichina</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">June 2018</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://fulltxt.org/article/678</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">10</style></volume><pages><style face="normal" font="default" size="100%">611-619</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; Ever since ancient times, medicinal plants recognized as major source of therapeutics, as rescue for human diseases and maintain health. There is an exponential increase in usage of green medicines due to less cost and fewer side effects. The family Pinaceae, is largest conifer in species diversity. Pinus is the largest genus of monoecious, resiniferous, evergreen trees commonly known as Pines. Three species of pines occur wild in Indian Himalayas &lt;em&gt;Pinus roxburghii, Pinus wallichiana , Pinus gerardiana&lt;/em&gt;. In addition, the constituents present in these plants are beneficial for the purpose of treatment of various ailments. &lt;strong&gt;Methods:&lt;/strong&gt; Information was collected from scientific journals, books, and reports via electronic search tools( Medline, Pubmed etc.) &lt;strong&gt;Results:&lt;/strong&gt; This review summarizes the existing information on three species of Pinus in relation to their pharmacognostic properties, phytochemistry, ethanopharmacology and pharmacological activities.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Review Article</style></work-type><section><style face="normal" font="default" size="100%">611</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Aditi Sharma, Lalit Sharma, Rohit Goyal* &lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;School of Pharmaceutical Sciences, Shoolini University, Solan, Himachal Pradesh, INDIA.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Anirban Chouni</style></author><author><style face="normal" font="default" size="100%">Santanu Paul</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">A Review on Phytochemical and Pharmacological Potential of Alpinia galanga</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">1’s’-1’- Acetoxychavicolacetate</style></keyword><keyword><style  face="normal" font="default" size="100%">Alpinia galanga</style></keyword><keyword><style  face="normal" font="default" size="100%">Anticancer</style></keyword><keyword><style  face="normal" font="default" size="100%">Antimicrobial</style></keyword><keyword><style  face="normal" font="default" size="100%">Bioactivity</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">December 2017</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://fulltxt.org/article/357#ref28</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">10</style></volume><pages><style face="normal" font="default" size="100%">09-15</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; From the ancient Vedic era, green plants are being used for their medicinal properties to treat several diseases. Green plants represent a big source of bioactive compounds. &lt;em&gt;Alpinia galanga&lt;/em&gt; (Linn.) of Zingiberaceae family is one amongst those medicinally important plants. Different parts of the plant are used in the treatment of many diseases for its anti-fungal, anti-tumour, antimicrobial, anti-inflammatory, anti-diabetic, antioxidant, antiulcer and many other properties. Several active compounds such as 1&amp;rsquo;S-1&amp;rsquo;-acetoxychavicol acetate, 1&amp;rsquo;S-1&amp;rsquo;-acetoxyeuginol acetate, 1, 8-cineol, &amp;alpha;-fenchyl acetate, &amp;beta;-farnesene, &amp;beta;-bisabolene, &amp;alpha;-bergamotene, &amp;beta;-pinene, &amp;beta;-Sitosteroldiglucoside (AG-7), &amp;beta;-sitsterylArabinoside (AG-8), 1&amp;rsquo;-acetoxychavicol acetate (galangal acetate), p-hydroxycinnamaldehyde has been extracted from the plant. &lt;strong&gt;Methods:&lt;/strong&gt; Relevant information was collected from scientific journals, books, and reports via electronic search using Medline, PubMed, Science Direct and Scopus. &lt;strong&gt;Results:&lt;/strong&gt; This review provides a comprehensive report on &lt;em&gt;Alpinia galanga&lt;/em&gt; having anti-proliferative, apoptotic, anti angiogenic as well as cytotoxic efficacy and their mode of action &lt;em&gt;in vitro&lt;/em&gt; as well as &lt;em&gt;in vivo&lt;/em&gt; condition. &lt;strong&gt;Conclusion:&lt;/strong&gt; Considering the ability of the golden treasure present in &lt;em&gt;Alpinia galanga&lt;/em&gt;, this review is aimed to summarize the information of the chemical constituents, pharmacological and therapeutic effects of the plant.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Review Article</style></work-type><section><style face="normal" font="default" size="100%">9</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Anirban Chouni and Santanu Paul*&lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;Laboratory of Cell and Molecular Biology, Department of Botany, University of Calcutta, Kolkata 700019, West Bengal, INDIA.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Prasad Kadam</style></author><author><style face="normal" font="default" size="100%">Manohar Patil</style></author><author><style face="normal" font="default" size="100%">Kavita Yadav</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">A Review on Phytopharmacopial Potential of Epilobium angustifolium</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Biological activities</style></keyword><keyword><style  face="normal" font="default" size="100%">Epilobium angustifolium L</style></keyword><keyword><style  face="normal" font="default" size="100%">Herbaceous</style></keyword><keyword><style  face="normal" font="default" size="100%">Oenothein B</style></keyword><keyword><style  face="normal" font="default" size="100%">Pharmacological Effects</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">August 2018</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">10</style></volume><pages><style face="normal" font="default" size="100%">1076-1078</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;Nature has been a source of medicinal agents for thousands of years, and an impressive number of modern drugs have been isolated from natural sources which are based on their use in traditional medicine.&lt;em&gt; Epilobium angustifolium&lt;/em&gt; L is a perennial herbaceous plant that belongs to the &lt;em&gt;Onagraceae&lt;/em&gt; family. It exhibits various therapeutic properties like anticancer, antibacterial, anti-inflammatory, antioxidant, and anti-aging properties. &lt;em&gt;Epilobium angustifolium&lt;/em&gt; L. contains polyphenols and secondary metabolites like oenothein B. Information was collected via Medline, PubMed, and Science Direct. Also some data have been collected from scientific journals, books, and reports. This review gives the current information on the chemical composition, traditional uses, and documented biological activities of &lt;em&gt;Epilobium angustifolium&lt;/em&gt; L. These studies reveal that &lt;em&gt;Epilobium&lt;/em&gt; &lt;em&gt;angustifolium&lt;/em&gt; L is a source of medicinally active compounds and have various pharmacological effects. These studies will be helpful to create interest toward&lt;em&gt; Epilobium angustifolium&lt;/em&gt; L and may be useful in developing a new direction for further research.&lt;em&gt;Epilobium angustifolium&lt;/em&gt; L.is a medicinally important plant belongs to &lt;em&gt;Onagraceae&lt;/em&gt; family. Extract from the plant is used in the treatment of many diseases for its anti-tumor, antimicrobial, anti-inflammatory, antioxidant, anti-ulcer and many other properties. The medicinal properties of fireweed have been attributed to its high content in polyphenols and more particularly to the most abundant of its secondary metabolites: Oenothein B.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Review Article</style></work-type><section><style face="normal" font="default" size="100%">1076</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Prasad Kadam&lt;sup&gt;1&lt;/sup&gt;*,&amp;nbsp;Manohar Patil&lt;sup&gt;2&lt;/sup&gt;,&amp;nbsp;Kavita Yadav&lt;sup&gt;1&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmacognosy, Associate Professor, Marathwada Mitra Mandal&amp;rsquo;s College of Pharmacy, Pune- 411033, Maharashtra, INDIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Pharmacognosy, Principal and Professor of Pharmacognosy, Marathwada Mitra Mandal&amp;rsquo;s College of Pharmacy, Pune-411033, Maharashtra, INDIA.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Rashmi Kaup Shiva</style></author><author><style face="normal" font="default" size="100%">Ganaraja Bolumbu</style></author><author><style face="normal" font="default" size="100%">Santosh Mayannavar</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Role of Catecholamine Pathways in Action of Orexin B Induced Open Field Activity by Nucleus Accumbens in Wistar Rats</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Dopamine</style></keyword><keyword><style  face="normal" font="default" size="100%">Noradrenaline</style></keyword><keyword><style  face="normal" font="default" size="100%">Nucleus Accumbens</style></keyword><keyword><style  face="normal" font="default" size="100%">Orexin B</style></keyword><keyword><style  face="normal" font="default" size="100%">TCSOX2- 29</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">June 2018</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://fulltxt.org/article/641</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">10</style></volume><pages><style face="normal" font="default" size="100%">628-632</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Aims:&lt;/strong&gt; To elucidate whether exploratory behaviour changes following Orexin B infusion in NAc is mediated through catecholamines in male Wistar rats. &lt;strong&gt;Methods:&lt;/strong&gt; Inbred male Wistar rats (n= 24) were divided into three groups. Control, Treated 1 (Orexin B) and Treated 2 (Orexin B antagonist) groups. Using stereotaxic method, guide cannula was set in place bilaterally to reach Nucleus Accumbens. Orexin B and its antagonist, TCS-OX2-29 were infused in separate groups of overnight fasted rats. Following open field activity, catecholamines (Dopamine, Adrenaline, and Noradrenaline) were estimated in brain tissue homogenate by ELISA. Data were expressed as mean&amp;plusmn;SEM (ANOVA; Student-Newman Keuls test,).p&amp;lt;0.05 were considered as statistically significant. &lt;strong&gt;Results:&lt;/strong&gt; Orexin B infusion significantly increased noradrenaline levels in Nucleus accumbens when compared to controls. TCS-OX2-29 significantly decreased noradrenaline in Nucleus accumbens during open field exploration activity. Adrenaline was not altered significantly during open field activity. &lt;strong&gt;Conclusion:&lt;/strong&gt; These results suggest that Orexin B, which plays a role in the regulation of motor and exploratory behaviour when infused in NAc mediates these actions through noradrenergic neurotransmission in Nucleus Accumbens.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">628</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Rashmi Kaup Shiva&lt;sup&gt;1&lt;/sup&gt;, Ganaraja Bolambu&lt;sup&gt;2&lt;/sup&gt;*, Santosh Mayannavar&lt;sup&gt;3 &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Physiology, Centre for Basic Sciences, Kasturba Medical College (A unit of Manipal Academy of Higher Education (MAHE), Manipal), Mangalore, Karnataka, INDIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Physiology, Karwar Institute of Medical Sciences, Karwar, Karnataka, INDIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Oral and Maxillofacial Surgery, Manipal College of Dental Sciences, Mangaluru, Karnataka, INDIA.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Asser Ashraf Ahmad</style></author><author><style face="normal" font="default" size="100%">Ihab Ibrahim Al Khalifa</style></author><author><style face="normal" font="default" size="100%">Zead Helmi Abudayeh</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">The Role of Pomelo Peel Extract for Experimentally Induced Wound in Diabetic Rats</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Flavonoids</style></keyword><keyword><style  face="normal" font="default" size="100%">Peel</style></keyword><keyword><style  face="normal" font="default" size="100%">Pomelo</style></keyword><keyword><style  face="normal" font="default" size="100%">Vitamin C</style></keyword><keyword><style  face="normal" font="default" size="100%">Wound</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">August 2018</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">10</style></volume><pages><style face="normal" font="default" size="100%">885-891</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; Delayed wound healing is a chronic complication in diabetic patients than in healthy individuals. Pomelo belongs to the genus Citrus of the family Rutaceae, an important fruit with great benefits for humans in the world. Previous studies showed that pomelo peels contain an abundant bioactive compound, which may promote wound healing in experimental animals. &lt;strong&gt;Aim:&lt;/strong&gt; The current study was carried to prepare optimized extraction of pomelo peels using different experimental conditions and investigate the possible healing effect of oral treatment with pomelo peel extract (PPE) on induced excision skin wound in diabetic rats. &lt;strong&gt;Materials and Methods:&lt;/strong&gt; This study was done on rats divided into five groups each of 8 rats (two treatment groups given PPE (400 and 600) mg/kg by oral gavage compared to two control groups and standard plant for wound healing). Diabetes was induced by intraperitoneal injection of a single dose of Streptozotocin (STZ) 65 mg\kg body weight. After diabetes induction, full thickness excision wound was made in rats, and the study continued for 3 weeks.&lt;strong&gt; Results:&lt;/strong&gt; This study showed significant reduction in blood glucose and both percentage and time to wound closure in the treated groups, also a significant increase in hydroxyproline and total protein content of the healed wound tissue in the treated groups compared with control groups and comparable to standard plant extract treated groups. &lt;strong&gt;Conclusion:&lt;/strong&gt; Experimental data proposed that oral administration of pomelo peel extract rich in vitamins and flavonoids has a good therapeutic potential in the treatment of complicated wounds in diabetes.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">885</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Asser Ashraf Ahmad&lt;sup&gt;1&lt;/sup&gt;, Ihab Ibrahim Al Khalifa&lt;sup&gt;2&lt;/sup&gt;, Zead Helmi Abudayeh&lt;sup&gt;3&lt;/sup&gt;*&lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmacy Science / pharmacology /Applied Pharmaceutical Science and Clinical Pharmacy/ Faculty of Pharmacy, Al-Isra University, Amman, JORDAN.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Pharmacology and Toxicology/Pharmacy/AL-Rasheed University, Baghdad, IRAQ.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Pharmaceutical Chemistry and Pharmacognosy/ Applied Pharmaceutical Science and Clinical Pharmacy Department / Faculty of Pharmacy, Al-Isra University, Amman, JORDAN.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Sushma Devi</style></author><author><style face="normal" font="default" size="100%">Randhir Singh</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">RETRACTED: Antioxidant and Anti-Hypercholesterolemic Potential of Vitis vinifera Leaves</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antioxidant</style></keyword><keyword><style  face="normal" font="default" size="100%">Cholesterol Diet</style></keyword><keyword><style  face="normal" font="default" size="100%">Hypercholesterolemia</style></keyword><keyword><style  face="normal" font="default" size="100%">Total Phenolic Content Etc.</style></keyword><keyword><style  face="normal" font="default" size="100%">Vitis vinifera</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2017</style></year></dates><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Background:&lt;/strong&gt; Grapes (&lt;em&gt;Vitis vinifera)&lt;/em&gt; are universally appreciated fruit for their delicacy, nutrition and accepted as functional food. The objective of the present study is to evaluate antioxidant and anti-hypercholesterolemic potential of &lt;em&gt;Vitis vinifera&lt;/em&gt; leaves extract. &lt;strong&gt;Methods:&lt;/strong&gt; Qualitative and quantitative phytochemical screening of methanolic (VVME) and aqueous (VVAE) extract was carried out to identify the phytoconstituents. Antioxidant potential was evaluated by employing &lt;em&gt;in-vitro&lt;/em&gt; and &lt;em&gt;in vivo&lt;/em&gt; assays. The anti-hypercholesterolemic activity was evaluated by inducing hypercholesterolemia with high cholesterol diet for 21 days in experimental animals. &lt;strong&gt;Results:&lt;/strong&gt; In VVME, total tannins, total flavonoids and total phenolic contents were found to be present in major amount. Both extract has significant in-vitro and in-vivo antioxidant efficacy. Different doses i.e. 100, 200 and 400 mg/kg of VVME and VVAE significantly attenuated the lipid levels. Moreover, VVME was found to be more effective as compared to VVAE and also, effectiveness was confirmed with histological results. &lt;strong&gt;Conclusion:&lt;/strong&gt; It can be concluded that antioxidant and anti-hypercholesterolemic efficacy of &lt;em&gt;Vitis vinifera&lt;/em&gt; might be due to presence of antioxidant property and active phytoconstituents.&lt;/p&gt;
</style></abstract><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Sushma Devi and Randhir Singh&lt;sup&gt;* &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p&gt;Department of Pharmaceutical Sciences, Maharishi Markandeshwar University, Mullana, Ambala, INDIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Tom Mathew Kalappurayil</style></author><author><style face="normal" font="default" size="100%">Benny Pulinilkkumthadathil Joseph</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">A Review of Pharmacognostical Studies on Moringa oleifera Lam. flowers</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Bioactivity</style></keyword><keyword><style  face="normal" font="default" size="100%">Bioassay</style></keyword><keyword><style  face="normal" font="default" size="100%">Extracts</style></keyword><keyword><style  face="normal" font="default" size="100%">Flower</style></keyword><keyword><style  face="normal" font="default" size="100%">GCMS</style></keyword><keyword><style  face="normal" font="default" size="100%">Moringa</style></keyword><keyword><style  face="normal" font="default" size="100%">Phytochemicals</style></keyword><keyword><style  face="normal" font="default" size="100%">Therapeutic</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2017</style></year><pub-dates><date><style  face="normal" font="default" size="100%">December 2016</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">/files/PJ-9-3/10.5530pj.2017.1.1</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">9</style></volume><pages><style face="normal" font="default" size="100%">1-7</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align:justify&quot;&gt;&lt;em&gt;Moringa oleifera&lt;/em&gt; Lam. of the family Moringaceae, popularly called &amp;lsquo;miracle tree&amp;rsquo; is a native of sub Himalayan tracts of Northern India and is widely cultivated in tropical and subtropical regions. Research on Moringa mainly pivoted around its leaves and seeds because of their immense nutraceutical potential but recently there is a greater interest in flowers too, mostly inspired by the positive outcomes of several pharmacognostical studies on flowers. Moringa flower is a rich reservoir of bioactive phytochemicals and crude flower extracts showed promising antibacterial, antifungal, anti larval, antioxidant, anti inflammatory and anticancer properties. This review concisely presents the various phytochemicals identified and isolated as well as the various bioassays employed to validate the therapeutic potential of flower. It is prepared after a detailed search on Google scholar. Reports on &lt;em&gt;Moringa oleifera&lt;/em&gt; flower were sorted and tabulated based on the bioassays performed and solvents used for extraction. A grading pattern is adopted for comparing efficiency of different extracts in eliciting bioactivities. Many of these studies are at the preliminary stage but two of them present advanced mechanisms. First is the presence of a proteinaceous larvicidal compound &amp;lsquo;MoFTI&amp;rsquo; in the flower capable of inhibiting larval trypsin of &lt;em&gt;Aedes aegypti&lt;/em&gt;. The second describes flower extract&amp;rsquo;s anti inflammatory mechanism effecting via NF-KB pathway and consequent suppression of inflammatory mediators&amp;rsquo; activation, but short of identifying lead compound/compounds behind this effect. Thus authors suggest further studies to elucidate the detailed mechanisms, identify and isolate the active compound or compounds of synergism behind the many therapeutic potential of the Moringa flower extracts.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Review Article</style></work-type><section><style face="normal" font="default" size="100%">1</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Tom Mathew Kalappurayil&lt;sup&gt;*&lt;/sup&gt;, Benny Pulinilkkumthadathil Joseph&lt;/strong&gt;&lt;/p&gt;

&lt;p style=&quot;text-align: justify;&quot;&gt;Department of Zoology, St Thomas College, Pala PIN 686574, Kottayam district, Kerala, INDIA&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Reena Kulkarni</style></author><author><style face="normal" font="default" size="100%">Suhas Kumar Shetty</style></author><author><style face="normal" font="default" size="100%">Rajarajeshwari N M</style></author><author><style face="normal" font="default" size="100%">Prasanna Narasimha Rao</style></author><author><style face="normal" font="default" size="100%">Nayan J</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Rasayana Herbs of Ayurveda to Treat age Related Cognitive Decline: An Update</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Ayurveda</style></keyword><keyword><style  face="normal" font="default" size="100%">cognitive decline</style></keyword><keyword><style  face="normal" font="default" size="100%">Dementia</style></keyword><keyword><style  face="normal" font="default" size="100%">Herbs</style></keyword><keyword><style  face="normal" font="default" size="100%">Medhya</style></keyword><keyword><style  face="normal" font="default" size="100%">Rasayana.</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2016</style></year><pub-dates><date><style  face="normal" font="default" size="100%">Oct 2016</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">8</style></volume><pages><style face="normal" font="default" size="100%">411-423</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;Cognitive decline associated with aging could be minor or major neuro-cognitive disorder presenting with progressive intellectual deterioration interfering with day to day activities. Behaviour and personality changes may complicate the life in due course. Significant increase in global prevalence of people aged above 60 years has raised concerns on effective management of old age problems. Age related cognitive deficits and dementia raise to the level of epidemics and established management is yet underway. Principles of preventive health and rasayana (rejuvenative) herbs of Ayurveda are being extensively researched up on for their effectiveness in dementia. In this fourteen such herbs with anti dementia property are discussed with relevant research update. &lt;strong&gt;Methods:&lt;/strong&gt; Herbs like amalaki (&lt;em&gt;Emblica officinalis&lt;/em&gt;), hareetaki (&lt;em&gt;Terminalia chebula&lt;/em&gt;), haridra (&lt;em&gt;Curcuma longa&lt;/em&gt;), manduka parni (&lt;em&gt;Centella asiatica&lt;/em&gt;), aindri (&lt;em&gt;Bacopa monniera&lt;/em&gt;), yastimadhu (&lt;em&gt;Glycirrhiza glabra&lt;/em&gt;), guduchi (&lt;em&gt;Tinospora cordifolia&lt;/em&gt;), shankhapushpi (&lt;em&gt;Convolvulus pleuricaulis&lt;/em&gt;), vacha (&lt;em&gt;Acorus calamus&lt;/em&gt;), jyotishmati (&lt;em&gt;Celastrus panniculata&lt;/em&gt;), kushmanda (&lt;em&gt;Benincasa hispida&lt;/em&gt;), Jatamamsi (&lt;em&gt;Nardostachys jatamamsi&lt;/em&gt;), ashvagandha (&lt;em&gt;Withania somnifera&lt;/em&gt;) and kapikacchu (&lt;em&gt;Mucuna pruriens&lt;/em&gt; (&lt;em&gt;Linn&lt;/em&gt;.)) are already proven of their efficacy in experimental and preclinical levels. The contents and research evidences are collected from ayurveda database on medicinal plants used in Ayurveda and Siddha and other authentic literature, Google scholar, Science direct, online and print journals. &lt;strong&gt;Discussion:&lt;/strong&gt; The herbs in discussion mostly act on reactive oxygen species and oxidative stress injury by antioxidant properties and neuroprotective activity. Acetylcholine esterase inhibition, N-Methyl-D-Aspartate antagonism, Dopaminergic activity, Anti-amyloidogenic activity, Inhibition of Tau aggregation, neuroprotection and immune modulation are activity path ways. Tridosha namely Kapha, Pitta and Vata may be viewed to be categorically predominant in initial, middle and final stage of dementia. Selected herbs thus can be specific based on the pathology and relevant dosha predominance.&lt;strong&gt; Conclusion: &lt;/strong&gt;Rasayana herbs with current updates and inferences can serve as an eye-opener for further researches at molecular and clinical aspect.&lt;/p&gt;

</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Review Article</style></work-type><section><style face="normal" font="default" size="100%">411</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Reena Kulkarni&lt;sup&gt;1*&lt;/sup&gt;, Suhas Kumar Shetty&lt;sup&gt;2&lt;/sup&gt;, Rajarajeshwari N M&lt;sup&gt;3&lt;/sup&gt;, Prasanna Narasimha Rao&lt;sup&gt;4&lt;/sup&gt; and Nayan J&lt;sup&gt;5 &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Kaumarabhritya, SDM College of Ayurveda, Tanniruhalla, Hassan-INDIA.&lt;/p&gt;

&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Manasa Roga, SDM College of Ayurveda, Tanniruhalla, Hassan-INDIA.&lt;/p&gt;

&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Samhita and Siddhanta, SDM College of Ayurveda, Tanniruhalla, Hassan-INDIA.&lt;/p&gt;

&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Department of Shalya Tantra, SDM College of Ayurveda, Tanniruhalla, Hassan-INDIA.&lt;/p&gt;

&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;5&lt;/sup&gt;Department of Agada tantra, Sri Kalabairaveshvara Swamy Ayurveda Medical College, RPC layout, Vijayanagar, Bengaluru-40, Karnataka, INDIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Gaurav Mahesh Doshi</style></author><author><style face="normal" font="default" size="100%">Pratip Kashinath Chaskar</style></author><author><style face="normal" font="default" size="100%">Hemant Devidas Une</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Revelation of β-sitosterol from Benincasa hispida Seeds, Carissa congesta Roots and Polyalthia longifolia Leaves by High Performance Liquid Chromatography</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Benincasa hispida</style></keyword><keyword><style  face="normal" font="default" size="100%">Carissa congesta</style></keyword><keyword><style  face="normal" font="default" size="100%">HPLC</style></keyword><keyword><style  face="normal" font="default" size="100%">Polyalthia longifolia</style></keyword><keyword><style  face="normal" font="default" size="100%">β-sitosterol.</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2016</style></year><pub-dates><date><style  face="normal" font="default" size="100%">September 2016</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">8</style></volume><pages><style face="normal" font="default" size="100%">610-613</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Background: &lt;/strong&gt;Fruit juice of &lt;em&gt;Benincasa hispida&lt;/em&gt; (BH) is regarded as &lt;em&gt;Vrindamadhava&lt;/em&gt; that is recommended for internal use in snake&amp;rsquo;s bites. The fruits have been reported to contain good amount of proteins, enzymes, Vitamin B&lt;sub&gt;1&lt;/sub&gt; and C&lt;sub&gt;1&lt;/sub&gt; flavonoid C-glycoside, terpenes, phenolic acids and free sugars such as glucose, rhamnose, mannitol, uronic acid, astilbin, catechin, naringenin, pectic polysaccharides and even some trace metals. &lt;em&gt;Polyalthia longifolia&lt;/em&gt; (PL) has been well known for its ayurvedic preparations such as &lt;em&gt;Sitaphala kula, Kaphapitashama, Anulomak and Krimighna&lt;/em&gt;. PL leaves has been reported to contain phytoconstituents like polylongine, Aporphine-Noxide alkaloids, allo-aromadendrene, caryophyllene oxide, &amp;beta;-caryophyllene, &amp;beta;-selinene, &amp;alpha;-humulene, &amp;alpha;-pinene and camphene. &lt;em&gt;Carissa congesta&lt;/em&gt; (CC), known as &lt;em&gt;Bengal currant&lt;/em&gt;, have yielded 2-acetyl phenol, carissone, carindone and Des-&lt;em&gt;n&lt;/em&gt;-methylnoracronycine. &amp;beta;-sitosterol, an important phytoconstituent recognized from all these selected plants has been well known for its ethnopharmacological importance. In this new study, the research team members has focused on determining the percentage of the &amp;beta;-sitosterol present in the BH seeds, CC roots and PL leaves by subjecting the extract to High Performance Liquid Chromatography (HPLC). &lt;strong&gt;Materials and Methods:&lt;/strong&gt; BH, CC and PL plants were shade-dried and extracted by suitable extraction methods. In HPLC, peaks obtained in the extracts were compared with the standard by matching their retention time. &lt;strong&gt;Results:&lt;/strong&gt; The amounts of &amp;beta;-sitosterol present in the BH seeds, CC roots and PL leaves extracts obtained at 254 nm were found to be 36.00, 7.46 and 3.21% w/w respectively. &lt;strong&gt;Conclusion: &lt;/strong&gt;Thus, BH, PL and CC extracts were said to contain &amp;beta;-sitosterol as a key constituent.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">610</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Gaurav Mahesh Doshi&lt;sup&gt;1&lt;/sup&gt;*, Pratip Kashinath Chaskar&lt;sup&gt;1&lt;/sup&gt;, Hemant Devidas Une&lt;sup&gt;2&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;

&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmacology and Pharmaceutical Chemistry, Vivekanand Education Society&amp;rsquo;s College of Pharmacy, Mumbai, INDIA.&lt;/p&gt;

&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Pharmacology, Y. B. Chavan College of Pharmacy, Rouzabagh, Aurangabad, Maharashtra, INDIA.&amp;nbsp;&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Janmejaya Samal</style></author><author><style face="normal" font="default" size="100%">Ranjit Kumar Dehury</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">A Review of Literature on Punarnavadi Mandura: An Ayurvedic Herbo-Mineral Preparation</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Anti-anemic</style></keyword><keyword><style  face="normal" font="default" size="100%">ASHA drugs kit.</style></keyword><keyword><style  face="normal" font="default" size="100%">Iron Deficiency Anemia</style></keyword><keyword><style  face="normal" font="default" size="100%">Naimithika Rasayana</style></keyword><keyword><style  face="normal" font="default" size="100%">Pharmacognostical</style></keyword><keyword><style  face="normal" font="default" size="100%">Phytochemical</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2016</style></year><pub-dates><date><style  face="normal" font="default" size="100%">January 2016</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">8</style></volume><pages><style face="normal" font="default" size="100%">180-184</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Background: &lt;/strong&gt;Punarnavadi Mandura is an Ayurvedic herbo-mineral preparation primarily used as an anemia correcting agent while its role in other clinical conditions has also been studied. &lt;strong&gt;Objective: &lt;/strong&gt;To understand the role of Punarnavadi Mandura in controlling anemia and other clinical conditions and its pharmacognostical and phytochemical properties. &lt;strong&gt;Methodology: &lt;/strong&gt;A search of literature was carried out using &amp;ldquo;Punarnavadi Mandura&amp;rdquo; as the only key word and a total of 33 literatures were obtained of which 5 titles were finally selected for the review. &lt;strong&gt;Results and Discussion: &lt;/strong&gt;Of the 5 studies identified 3 studies focused on the role of Punarnavadi Mandura as an anemia correcting agent, one study identified its role in other clinical condition (Diabetic Nephropathy), one study focused on the pharmacog&amp;shy;nostical and phytochemical analysis while one study focused on both the analysis of pharmacognostical and phytochemical properties and its role as an anemia correcting agent. As per these studies Punarnavadi Mandura is an effective remedy for iron deficiency anemia (IDA) of all ages. Statisti&amp;shy;cally significant result has been obtained in subjective and hematological parameters. Furthermore its role in other clinical conditions has also been found effective, especially in Diabetic Nephropathy (DN), as a &lt;em&gt;Naimithika Rasayana&lt;/em&gt;. Punarnavadi Mandura is currently a part of National health programme and is included in ASHA drugs kit for the management of IDA at community level. &lt;strong&gt;Conclusion: &lt;/strong&gt;Given the efficacy of Punarnavadi Mandura in IDA, at all ages, its usage should be fostered more in Indian communities especially the rural communities where IDA is endemic.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Review Article</style></work-type><section><style face="normal" font="default" size="100%">180</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Janmejaya Samal&lt;sup&gt;1&lt;/sup&gt;* and Ranjit Kumar Dehury&lt;sup&gt;2&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;

&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Research Consultant, International Union against Tuberculosis and Lung Disease (The union), Pune, Maharashtra, INDIA.&lt;/p&gt;

&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Healthcare Management, Faculty, Healthcare Management, Goa Institute of Management, Panaji, Goa, INDIA.&lt;/p&gt;

</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Juveriyah Kausar</style></author><author><style face="normal" font="default" size="100%">Durai Muthumani</style></author><author><style face="normal" font="default" size="100%">Agaath Hedina</style></author><author><style face="normal" font="default" size="100%">Sivasamy</style></author><author><style face="normal" font="default" size="100%">Vijaya Anand</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Review of the phytochemical and pharmacological activities of Euphorbia hirta Linn.</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Anti-apoptotic.</style></keyword><keyword><style  face="normal" font="default" size="100%">Anti-bacterial</style></keyword><keyword><style  face="normal" font="default" size="100%">Anti-oxidant</style></keyword><keyword><style  face="normal" font="default" size="100%">Diuretic</style></keyword><keyword><style  face="normal" font="default" size="100%">Euphorbia hirta</style></keyword><keyword><style  face="normal" font="default" size="100%">Sedative</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2016</style></year><pub-dates><date><style  face="normal" font="default" size="100%">June/2016</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">8</style></volume><pages><style face="normal" font="default" size="100%">310-313</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;The use of plant extract to cure diseases has been the traditional way used in many parts of the world. The synthetic drugs used now are more prone to cause side effects than curing the disease. Hence, the use of plant extract has now emerged due to their effective action against the disease without causing any side effects. The plants belonging to the family called Euphorbia are widely used in medicine for its wide medicinal properties. The plant &lt;em&gt;Euphorbia hirta&lt;/em&gt; has properties like anti-bacterial, anti-diarrheal, anti-allergic, diuretic, anti-oxidant, anti-tumor, anti-diabetic, anxiolytic and sedative activity. This review contains the detailed information about all the properties of &lt;em&gt;E. hirta.&lt;/em&gt;&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Review Article</style></work-type><section><style face="normal" font="default" size="100%">310</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Juveriyah Kausar &lt;sup&gt;1&lt;/sup&gt;, Durai Muthumani &lt;sup&gt;2&lt;/sup&gt;, Agaath Hedina &lt;sup&gt;1&lt;/sup&gt;, Sivasamy &lt;sup&gt;1&lt;/sup&gt;, Vijaya Anand &lt;sup&gt;1&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Human Genetics and Molecular Biology, Bharatiar University, Coimbatore &amp;ndash; 641 046, Tamil Nadu, INDIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Biochemistry, Kanchi Shri Krishna College of Arts and Science, Kilambi,&amp;nbsp;Kancheepuram &amp;ndash; 631 551, Tamil Nadu, INDIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Raj Bharath Rudrappan</style></author><author><style face="normal" font="default" size="100%">Krishnan Veeran</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Role of Plant Based Lectins in Identifying Rare Bombay Blood Group</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Blood grouping</style></keyword><keyword><style  face="normal" font="default" size="100%">Bombay phenotype</style></keyword><keyword><style  face="normal" font="default" size="100%">H antigen</style></keyword><keyword><style  face="normal" font="default" size="100%">Lectin</style></keyword><keyword><style  face="normal" font="default" size="100%">Ulex Europaeus.</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2016</style></year><pub-dates><date><style  face="normal" font="default" size="100%">09/2015</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">8</style></volume><pages><style face="normal" font="default" size="100%">70-71</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; Lectins are proteins found in a diversity of plants and organisms. They possess the ability to agglutinate erythrocytes with known carbohydrate specificity. &lt;strong&gt;Methods:&lt;/strong&gt; A lectin named Anti H is used in identification of a very rare and important blood group named Bombay blood group is extracted from the plant &lt;em&gt;Ulex europaeus&lt;/em&gt;. Our study was done to calculate the prevalence of Bombay blood group in our Indian population using the plant based extract lectin anti H. Blood grouping was done using the tube technique using commercially available antisera. &lt;strong&gt;Results:&lt;/strong&gt; Out of the total 11,512 blood samples collected and analysed, two samples were identified to be Bombay blood group. The prevalence of Bombay blood group in our study is .017%. The prevalence of the Bombay blood group varied slightly among different regions in parts of India. &lt;strong&gt;Conclusion: &lt;/strong&gt;Anti H Lectin helped in identifying Bombay Blood Group which would otherwise have been missed in routine blood grouping. Plant based lectins will perform an important role in the field of transfusion medicine in near future.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">70</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Raj Bharath Rudrappan&lt;sup&gt;*&lt;/sup&gt; and Krishnan Veeran &lt;/strong&gt;&lt;/p&gt;

&lt;p style=&quot;text-align: justify;&quot;&gt;Department of Plant Biology and Plant Biotechnology, Presidency College, Chennai 600005, Tamil Nadu, India.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Sharada Laxman Deore</style></author><author><style face="normal" font="default" size="100%">Bhushan Arun Baviskar</style></author><author><style face="normal" font="default" size="100%">Ashwini Suresh Rangari</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Rapid and high yield Extraction method for Saponins from Safed musli</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">HPTLC</style></keyword><keyword><style  face="normal" font="default" size="100%">Maceration Saponins</style></keyword><keyword><style  face="normal" font="default" size="100%">Microwave assisted solvent extraction</style></keyword><keyword><style  face="normal" font="default" size="100%">Orthogonal test L9 (34) Sonication</style></keyword><keyword><style  face="normal" font="default" size="100%">Taguchi Design</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2015</style></year><pub-dates><date><style  face="normal" font="default" size="100%">Jul-Aug 2015</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">7</style></volume><pages><style face="normal" font="default" size="100%">210-214</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Objectives: &lt;/strong&gt;We aimed to develop, compare and optimise rapid and high yield extraction method for saponins of Safed musli using conventional extraction techniques and as well as modern microwave assisted solvent extraction method. &lt;strong&gt;Materials and methods: &lt;/strong&gt;Roots of Safed musli (Chlorophytum borivilianum) are extracted by maceration, soxhlet, sonication and microwave methods. Extract further fractionated to obtain total saponins. Microwave assisted solvent extraction (MASE) method is optimised using Taguchi L9 orthogonal array design. Total saponins are estimated by High Performance Thin Layer chromatography (HPTLC) from all extracts obtained by different methods. &lt;strong&gt;Results: &lt;/strong&gt;Factors namely temperature, irradiation time, irradiation power and powder size which potentially affects extraction efficiency are considered while optimizing MASE by statistical orthogonal array design procedure and saponins are quantified using HPTLC. Under developed optimum conditions, MASE showed significantly higher yield (5.11%) and drastic reduction in extraction time (4 min) than conventional extraction methods.&lt;strong&gt; Conclusion: &lt;/strong&gt;Saponins of Safed musli shown highest yield in MASE and then maceration, soxhlet and sonication followed. The developed and optimised method of saponin extraction by MASE can have huge industrial applications after scale up.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">210</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Sharada Laxman Deore*, Bhushan Arun Baviskar and Ashwini Suresh Rangari &lt;/strong&gt;Department of Pharmacognosy, Government College of Pharmacy, Kathora Naka, Amravati &amp;ndash; 444604, MS, INDIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Sharada Laxman Deore</style></author><author><style face="normal" font="default" size="100%">Bhushan Arun Baviskar</style></author><author><style face="normal" font="default" size="100%">Ashwini Suresh Rangari</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Rapid and high yield Extraction method for Saponins from Safed Musli</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">HPTLC</style></keyword><keyword><style  face="normal" font="default" size="100%">Maceration Saponins</style></keyword><keyword><style  face="normal" font="default" size="100%">Microwave assisted solvent extraction</style></keyword><keyword><style  face="normal" font="default" size="100%">Orthogonal test L9 (34) Sonication</style></keyword><keyword><style  face="normal" font="default" size="100%">Taguchi Design.</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2015</style></year><pub-dates><date><style  face="normal" font="default" size="100%">16th Jan, 2015</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">7</style></volume><pages><style face="normal" font="default" size="100%">210-214</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Objectives:&lt;/strong&gt; We aimed to develop, compare and optimise rapid and high yield extraction method for saponins of safed musli using conventional extraction techniques and as well as modern microwave assisted solvent extraction method.&lt;strong&gt; Materials and methods:&lt;/strong&gt; Roots of Safed musli (&lt;em&gt;Chlorophytum borivilianum&lt;/em&gt;) are extracted by maceration, soxhlet, sonication and microwave methods. Extract further fractionated to obtain total saponins. Microwave assisted solvent extraction (MASE) method is optimised using Taguchi L9 orthogonal array design. Total saponins are estimated by High Performance Thin Layer chromatography (HPTLC) from all extracts obtained by different methods. &lt;strong&gt;Results:&lt;/strong&gt; Factors namely temperature, irradiation time, irradiation power and powder size which potentially affects extraction efficiency are considered while optimizing MASE by statistical orthogonal array design procedure and saponins are quantified using HPTLC. Under developed optimum conditions, MASE showed significantly higher yield (5.11%) and drastic reduction in extraction time (4 min) than conventional extraction methods. &lt;strong&gt;Conclusion:&lt;/strong&gt; saponins of safed musli shown highest yield in MASE and then maceration, soxhlet and sonication followed. The developed and optimised method of saponin extraction by MASE can have huge industrial applications after scale up.&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Key words:&lt;/strong&gt; HPTLC, Microwave assisted solvent extraction, Maceration Saponins, Orthogonal test L9 (34) Sonication, Taguchi Design.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">210</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Sharada Laxman Deore&lt;sup&gt;*&lt;/sup&gt;, Bhushan Arun Baviskar and Ashwini Suresh Rangari &lt;/strong&gt;&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;Department of Pharmacognosy, Government College of Pharmacy, Kathora Naka, Amravati &amp;ndash; 444604, MS, INDIA.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">D. Sathis Kumar,</style></author><author><style face="normal" font="default" size="100%">David Banji,</style></author><author><style face="normal" font="default" size="100%">A. Harani,</style></author><author><style face="normal" font="default" size="100%">Ch. Pavan Kumar,</style></author><author><style face="normal" font="default" size="100%">JN. Ravi Varma</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Role of Boswellia ovalifoliolata Bal. Henry extract on high fat diet induced hypercholesterolemia</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Boswellia Ovalifoliolata Bal. Henry</style></keyword><keyword><style  face="normal" font="default" size="100%">High Fat Diet</style></keyword><keyword><style  face="normal" font="default" size="100%">lipid profile</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2014</style></year><pub-dates><date><style  face="normal" font="default" size="100%">8th April 2014</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">6</style></volume><pages><style face="normal" font="default" size="100%">108-116</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Objective:&lt;/strong&gt; To evaluate the Antihypercholesterolemic effect of &lt;em&gt;Boswellia ovalifoliolata&lt;/em&gt; Bal. Henry extract by performing &lt;em&gt;in vivo&lt;/em&gt; studies and to check out its effects by evaluating parameters like food consumption, weight gain, fecal fat excretion, serum and liver lipid &amp;amp;biochemical profiles. Even the study includes confirmation of activity by the histopathological studies. &lt;strong&gt;Methods: &lt;/strong&gt;Animals were fed with cholesterol rich high fat diet. Food intake, Body weight and fecal fat excretion were measured. Serum and liver samples were analyzed for the estimation of lipid profiles and other biochemical parameters by using different kits. Histopathological study on liver, aorta, heart and adipose tissue was done to ensure the activity.&lt;strong&gt; Results:&lt;/strong&gt; The animal group administered with methanolic extract of the plant has shown decreased levels of TC, LDL, VLDL, TG, HDL+VLDL, VLDL+LDL, LDL/TC, AI, SGOT, SGPT and elevated levels of HDL, HDL/TC in a dose dependent manner significantly (p&amp;lt;0.01 &amp;amp; p&amp;lt;0.05). The evaluation of liver tissue of animal groups treated with herbal extract and standard had shown increased levels of SOD, GSH and Catalase, whereas levels of SGOT, SGPT, Total glucose, HMG-CoA, lipase, amylase and percentage of monaldehyde were decreased when compared with high fat diet fed rats. Body weight and Food intake in treated groups were significantly lower than that in model control. &lt;strong&gt;Conclusion:&lt;/strong&gt; It can be confered from the present studies that the &lt;em&gt;Boswellia ovalifoliolata&lt;/em&gt; Bal. Henry extract have strong activity against hypercholesterolemia and obesity suggesting a potential benefit as antihypercholesterolemic agent.&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;key words&lt;/strong&gt;: &lt;em&gt;Boswellia ovalifoliolata&lt;/em&gt; Bal. Henry, High fat diet, Lipid profile, Histopathological studies.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;D. Sathis Kumar&lt;sup&gt;1,2*&lt;/sup&gt;, David Banji&lt;sup&gt;3&lt;/sup&gt;, A. Harani&lt;sup&gt;4&lt;/sup&gt;, Ch. Pavan Kumar&lt;sup&gt;1&lt;/sup&gt; and JN. Ravi Varma&lt;/strong&gt;&lt;sup&gt;&lt;strong&gt;4&lt;/strong&gt;&lt;/sup&gt;&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Aditya Institute of Pharmaceutical Sciences and Research, Surampalem, Andhra Pradesh, India-533437&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Jawaharlal Nehru Technical University, Hyderabad, Andhra Pradesh, India&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Nalanda College of Pharmacy, Nalgonda, Andhra Pradesh, India-508001&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;A.U. College of Pharmaceutical Sciences, Andhra University, Visakhapatnam, India-530003.&lt;/p&gt;</style></auth-address></record></records></xml>