ArticleViewAbstractPharmacognosy Journal,2016,8,3,215-219.DOI:10.5530/pj.2016.3.6Published:January 2016Type:Original ArticlePharmaco-Chemical characterization and Acaricidal Activity of Ethanolic Extract of Chassalia Curviflora (Wall ex Kurz.) Thwaites.Ajeesh Krishna Thumadath Palayullaparambil, Adarsh Krishna Thumadath Palayullaparambil, Sanis Juliet, Kumuthakalavalli Renganathan, Ramasubbu Raju, Sunil Athalathil, Reghu Ravindran, Leena Chandrashekar, Suresh Narayanan Nair, and Srikanta Ghosh Ajeesh Krishna Thumadath Palayullaparambil1, Adarsh Krishna Thumadath Palayullaparambil2, Sanis Juliet2*, Kumuthakalavalli Renganathan1, Ramasubbu Raju1, Sunil Athalathil2, Reghu Ravindran3, Leena Chandrashekar4, Suresh Narayanan Nair2, Srikanta Ghosh5 1Department of Biology, The Gandhigram Rural Institute-Deemed University, Gandigram, Dindigul-624 302, Tamil Nadu, INDIA. 2Department of Veterinary Pharmacology and Toxicology, College of Veterinary and Animal Sciences, Kerala Veterinary and Animal Sciences University, Pookode-673 576, Wayanad, Kerala, INDIA. 3Department of Veterinary Parasitology, College of Veterinary and Animal Sciences, Kerala Veterinary and Animal Sciences University, Pookode-673 576, Wayanad, Kerala, INDIA. 4Department of Anatomy and Histology, College of Veterinary and Animal Sciences, Kerala Veterinary and Animal Sciences University, Pookode-673 576, Wayanad, Kerala, INDIA. 5Division of Parasitology, Indian Veterinary Research Institute, Izatnagar, UP243122, INDIA. Abstract:Introduction: C. curviflora, an important ethno-medicinal plant used by the Kurichia local people in Western Ghats region of Wayanad is yet to be explored pharmacologically. It is used as paste on the body of cattle and birds for curing skin diseases. Objectives: To characterize the pharmacochemical features and to study the acaricidal effect of ethanolic extract of C. curviflora on engorged female ticks of R. (B.) annutatus. Methods: The pharmaco-chemical features such as physico-chemical, proximate, phytochemical, fluorescence, and HPTLC profiling were carried out using standard techniques. The pulverized leaves were subjected to soxhlet extraction using ethanol. The ethanolic extract at different concentrations (10% to 1.25%) was tested against ticks using adult immersion test (AIT). Result: The preliminary phytochemical investigation showed high contents of saponins, alkaloids and flavonoids. The HPTLC profiling of ethanolic extract showed the presence of 14 polyvalent components. Based on AIT, the extract at 10% revealed 43.76% of inhibition of fecundity (IF) and 29.16% of adult tick mortality. Conclusion: The results revealed that the extract has some active compounds that may influence in the reproductive system of female ticks. Keywords:Acaricidal activity, Chassalia curviflora, Fecundity., HPTLC, Pharmaco-chemical, R. (B.) annutatusView:PDF (188.75 KB) PDF Images Graphical Abstract ‹ Updates on Traditional Medicinal Plants for Hepatocellular Carcinoma up Evaluation of antioxidant effect and anticancer activity against human glioblastoma (U373MG) cell lines of Murraya Koenigii ›