Flavonoids of East Asian Species Serratula manshurica Kitag

Aim/ Background: The flavonoid composition of the East Asian species Serratula manshurica Kitag. (Family Asteraceae) growing in the Primorsky Territory, the Amur region and in the South of the Khabarovsk Territory of Russia was studied. Materials and Methods: Flavonoids quercetin-4’-O-β-D-glucuronopyranoside (1) and apigenin-7-O-β-D-glucuronopyranoside (2) were isolated from Serratula manshurica by methods of liquid extraction and recrystallization. The structures of the isolated compounds were identified by UV, NMR spectroscopy and mass spectrometry with electrospray ionization. Separation and quantitative content of flavonoids in the extracts of the aerial part (Leaves, stems, inflorescences) of Serratula manshurica was observed by RP HPLC. Results and Conclusion: The change in the amount of some flavonoids in various phenological phases in the overhead part of Serratula manshurica Kitag was studied. It was revealed that the maximum concentration of flavonoid aglycones in the plant was observed during the before budding in the budding period and their glycosides prevaily in the flowering phase. Widespread across the Far East, Serratula manshurica is promising and renewable source of bioactive compounds.