ArticleViewAbstractPharmacognosy Journal,2021,13,1,01-07.DOI:10.5530/pj.2021.13.1Published:January 2021Type:Original ArticleA New Ursane-Type Triterpene from the Fermented Shallot Allium AscalonicumNguyen Van Chuyen, Nguyen Hong Son, Pham Van Hien, Dang Truong Giang, Ho Ba Ngoc Minh, Ngo Thi Tuyet Mai, Chu Van Men, Ho Anh Son, and Vu Binh Duong Nguyen Van Chuyen#, Nguyen Hong Son#, Pham Van Hien, Dang Truong Giang, Ho Ba Ngoc Minh, Ngo Thi Tuyet Mai, Chu Van Men, Ho Anh Son*, Vu Binh Duong* Vietnam Military Medical University, 160 Phung Hung, Ha Dong District, Hanoi, VIETNAM. #These authors contributed equally to this work. Abstract:3,24-acetonideclethric acid (1), a new ursane-type triterpene, and four known compounds including ursolic acid (2), randiasaponin IV (3), ilekudinoside W (4) and (25S)-1β,3β,24β- trihydroxyspirost-5-en 1-O-α-L-rhamnopyranosyl-(1→2)- α-L-arabinopyranoside (5), and were isolated from the fermented shallot Allium ascalonicum. Their structures were determined by analysis of HR-ESI-MS, NMR spectral data, as well as comparison with those reported in the literature. All of the saponins (3-5) exhibited antimicrobial activity against three strains Staphylococcus aureus, Escherichia coli, and Candida albicans with IC50 values in the range from 89.49 ± 2.24 to 95.71 ± 3.86 μM. Keywords:24-Acetonideclethric acid, 3, Allium ascalonicum, Antimicrobial activity, SaponinView:PDF (963.33 KB) PDF Images Important HMBC and NOESY correlations of compound 1 ‹ Pharmacogn J, Vol 13, Issue 1, Jan-Feb, 2021 up Tinospora Sinensis (Lour.) Merr. Stem Modulate The TNF-Alpha Expression In HCT- 116 Tumour Cell, Besides the Inhibitory Effect on Cervical, Colon and Breast Cancer Cell Lines and Mycobacterium Tuberculosis H37Rv ›