ArticleViewAbstractPharmacognosy Journal,2024,16,3,538-544.DOI:10.5530/pj.2024.16.85Published:June 2024Type:Original ArticleRenal Resistive Index and Estimated Glomerular Filtration Rate in Nondiabetic Chronic Kidney Disease Stage 3: A Cross-Sectional Analytical StudyPatnaree Wongmanit, Kusuma Sriyakul, Parunkul Tungsukruthai, Ouppatham Supasyndh, and Pratya Phetkate Abstract:Background: Renal resistive index (RRI) and estimated glomerular filtration rate (eGFR) are predictive markers for chronic kidney disease (CKD) progression. Aim: To evaluate RRI value, eGFRcr-cys and renal biomarker in nondiabetic patients with CKD stage 3 in Bangkok, Thailand. Methods: A cross-sectional analytical analysis was conducted involving nondiabetic patients with CKD stage 3, aged 35-85 years. Ultrasound was used to assess the RRI of arteries in both kidneys. Patients underwent assessments of serum and urine 24-hour. Results: Among the 61 participants (67.2% male; mean age 69.03 ± 12.59 years), the mean eGFRcr-cys was 41.63 ± 8.64 mL/min/1.73 m², and the mean RRI was 0.65 ± 0.06. Patients were categorized into three RRI groups: low (<0.65, n=35), intermediate (0.65-0.70, n=14), and high (>0.70, n=12). The high RRI group showed a mean RRI of 0.73 ± 0.05 (p < 0.01). Among those with high RRI group were significant decreased right kidney size (p<0.05) and they had a lower BMI, averaging 22.49 ± 3.48. An increase in PP (59.66 ± 13.84, p=0.04) was also significant in this group. The correlations coefficient of RRI value showed a significant positive correlation with age (p<0.05) and significant negative with BMI (p<0.05). In addition, eGFRcr-cys displayed a significant negative correlation with UAGT and 24hUP (p<0.05) and a significant while eGFRcr-cys positive correlation with both kidney size and urine iNOS(p<0.01). Conclusion: An increase in RRI is inversely linked to age, BMI, and PP. Lower eGFR is correlated with factors that cause CKD progression. View:PDF (431.22 KB) PDF Images Calculation the renal resistive value index (RRI), where PSV is the peak systolic velocity and EDV is the end diastolic velocity. ‹ Inventory of Medicinal Plants for Male and Female Reproductive Health by Ethnic Javanese and Ethnic Dayak Seberuang in Balai Harapan Village, Tempunak District, Sintang Regency up Effect of Glutathione Supplementation in Cryoprotectant Modification on Tyrosine Phosphorylation, Acrosin Expression and Acrosome Reaction of Post-Thawing Spermatozoa Quality ›