ArticleViewAbstractPharmacognosy Journal,2025,17,2,244-251.DOI:10.5530/pj.2025.17.31Published:April 2025Type:Research ArticlePreparation, Characterization and Wound Healing Effect of β Chitosan and Gelatin Hydrogels from Sepia Officinalis: In Vivo StudyAmina DOUBBI BOUNOUA, Mokhtaria Yasmina BOUFADI, Karima BOUGUEROUA, and Soumia KEDDARI Amina DOUBBI BOUNOUA1, Mokhtaria Yasmina BOUFADI1,2,3*, Karima BOUGUEROUA1, Soumia KEDDARI1 1Laboratory of Bioeconomics, Food Safety and Health, Faculty of Natural Sciences and Life, University of Abdelhamid Ibn Badis, Mostaganem 27000, ALGERIA. 2Faculty of biology, University of Houari Boumediene USTHB Algiers 16000, ALGERIA. 3Laboratory of Pharmaceutical Chemistry, Faculty of Pharmacy, Libre university of Brussels, 1050 Brussels, BELGIUM. Abstract:Wound healing is a fundamental process through which the body repairs itself following damage to the skin's integrity. This process is intricate and involves multiple biological mechanisms. The objective of this study is to assess the wound healing properties of β-chitosan and gelatin hydrogels. Twenty-five rats were divided into five groups to facilitate the evaluation of wound closure rates and histopathological changes. Upon analyzing the results, we noted a decrease in the initial surface area of all wounds examined. The extent of contraction varied depending on the type of hydrogel used. By day 14, the contraction was most significant in the hydrogel (ch + gel) group (97.30%), followed closely by β-chitosan (96.72%) and gelatin (96.63%), as well as the cicatryl-bio treatment (92.76%). Keywords:Gelatin, Hydrogel, Os, Sepia Officinalis, Skin, Wound Healing, β ChitosanView:PDF (1.41 MB) PDF Images Wound creation ‹ Analysis of the Influence of Leadership Style on Organizational Culture and Organizational Performance at RSUD H. Andi Sulthan Daeng Radja Bulukumba District up Additional Feed of Moringa Oleifera Leaf Flour on the Development of Veterinary Embryos ›