ArticleViewAbstractPharmacognosy Journal,2019,11,4,689-693.DOI:10.5530/pj.2019.11.109Published:July 2019Type:Original ArticleEffectiveness of Moringa oleifea Extract in Attenuating the Toxic Effect on Platelet Count: An Experiment on Cadmium Exposed RatsVinodini NA, Pratik Kumar Chatterjee, Kunal, Suman VB, Rashmi KS, Nayanatara AK, Anupama N, Ramesh M. Bhat, and Sheela Joice P Vinodini NA1, Pratik Kumar Chatterjee1,*, Kunal1, Suman VB1, Rashmi KS1, Nayanatara AK1, Anupama N1, Ramesh M. Bhat1, Sheela Joice P2 1Department of Physiology, Kasturba Medical College, Mangalore, Manipal Academy of Higher Education (MAHE), Manipal, Karnataka, INDIA. 2Department of Physiology, MES Medical College, Perinthalmanna, Kerala, INDIA. Abstract:Aims and Objective: To determine the role of Moringa oleifera on total platelet count alterations (T-PC) in rats treated with cadmium. Materials and Methods: In the present study female adult Wistar Albino rats, (180-200) gm were divided into, Group I-normal control, Group II-pretreated control, group III-cadmium treated , group IV- pre-treated with Moringa oleifera leaf extract (MOE) and then administered oral cadmium for a day, with n=6 each Results: Indicate that the pre-treatment with MOE (100 mg/kg/bw) prior to cadmium infusion augmented the level of total platelet count (p≤0.001) as compared to the cadmium-exposed group, which might have a role in clotting mechanisms also. Conclusion: Moringa oleifera extract has a beneficial effect on platelet count in cadmium-induced animal model. Keywords:Cadmium, Clotting Mechanisms, Moringa oleifera, Platelet Count, ToxicityView:PDF (888.69 KB) PDF Images Graphical Abstract ‹ Exploration of Anti-Urolithiasis Potential of Traditional Siddha Formulations Amukkara Chooranam and Karisalai Karpam Chooranam by Struvite Crystal Growth Inhibition Assay up Free Radicals Scavenging Activity and Oxidative DNA Damage Protecting Property of Methanol Extract from Honeycrisp Apple ›