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The Interactive Antimicrobial Activity of Conventional Antibiotics and Petalostigma spp. Extracts Against Bacterial Triggers of some Autoimmune Inflammatory Diseases

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Antibacterial activity of P. pubescens (a) and P. triloculare (b) fruit and leaf extracts against P. mirabilis (ATCC: 21721) measured as zones of inhibition (mm). PP = P. pubescens; PT = P. triloculare; L = leaf; F = fruit; W = aqueous extract; M = methanolic extract; C = chloroform extract; H = hexane extract; E = ethyl acetate extract. Positive control = Amp (ampicillin 2μg) and Chl (chloramphenicol 10μg). Negative control (NC) = water. Results are expressed as mean zones of inhibition of at least six replicates (two repeats) ± SEM. * indicates results that are significantly different to the negative control (P<0.01).