ArticleViewAbstractPharmacognosy Journal,2021,13,6s,1568-1572.DOI:10.5530/pj.2021.13.200Published:December 2021Type:Original ArticleCharacterization and Phytochemical Screening of Meniran (Phyllanthus niruri Linn) Extract's Nanoparticles Used Ball Mill MethodEmy Koestanti Sabdoningrum, Sri Hidanah, Sri Chusniati, and Soeharsono Emy Koestanti Sabdoningrum*, Sri Hidanah, Sri Chusniati, Soeharsono Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, INDONESIA. Abstract:The aim of this study was to study the characterization and phytochemical screening of meniran (Phyllanthus niruri linn) extract's nanoparticles used ball mill method. The effect of herbal products would be maximized, a formulation that able to increase solubility, stability, bioavailability, and a targeted system was needed so the use of simplicia would be more effective. One of alternative solutions to this problem was to make the preparation of meniran extract in the form of nanoparticles. Nanoparticles made it easier for extract to be absorbed in blood plasma and were more effective in achieving the target drug itself. The manufacture of meniran nanoparticles used ball mill method. Then, meniran extract nanoparticles characterization and phytochemical screening were carried out. Meniran (Phyllanthus niruri Linn) extract nanoparticle characterization consisted of size, used Particle Size Analyzer (PSA), and morphology, used Scaning Electron Microscope (SEM). Phytochemical screening of meniran extract nanoparticles used qualitative screening by reagent test. The results showed that the meniran extract nanoparticles produced an average size of 192.6 nm. The averange shape of particle was imperfectly amorphous and the dominant composition was Carbon (C). Phytochemical screening showed the content of flavonoids, tannins, saponins, terpenoids and alkaloids. Keywords:Biological production, Nanoparticle, Phyllanthus niruri, Phytochemical compoundView:PDF (1.02 MB) PDF Images Meniran (Phyllanthus niruri Linn) phytochemical screening results A. Flavonoid, B. Tannin, C. Saponin, D. Trepenoid, E. Alkaloid. ‹ Alterations in Body Weight, Blood Glucose Levels, and Lipid Profiles in High-Fat Diet-Low Dose Streptozotocin-Induced Diabetic Rats up Role of Capsaicin in the Repair of Cellular Activity in Mice Liver ›