ArticleViewAbstractPharmacognosy Journal,2022,14,4,358-361.DOI:10.5530/pj.2022.14.107Published:August 2022Type:Original Article Amino Acid and Proximate Analysis of Type-1 Collagen from Sea Cucumber and Tilapia-Skin and its Potential Application as Artificial TendonArifia Safira, Cinta Atsa Mahesa Rani, Roro Ayu Puspitasari, Anindyta Kirana Putri Ayuningtyas, Yayang Amru Mahendra, Agus Purnomo, Faisal Fikri, Shekhar Chhetri, and Muhammad Thohawi Elziyad Purnama Arifia Safira1,5, Cinta Atsa Mahesa Rani1,5, Roro Ayu Puspitasari1,5, Anindyta Kirana Putri Ayuningtyas1,5, Yayang Amru Mahendra1,5, Agus Purnomo2, Faisal Fikri3,5, Shekhar Chhetri4, Muhammad Thohawi Elziyad Purnama1,5,* 1Division of Veterinary Anatomy, Department of Veterinary Science, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, INDONESIA. 2Department of Veterinary Surgery and Radiology, Faculty of Veterinary Medicine, Universitas Gadjah Mada, Yogyakarta, INDONESIA. 3Division of Physiology and Pharmacology, Department of Veterinary Science, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, INDONESIA. 4Department of Animal Science, College of Natural Resources, Royal University of Bhutan, Lobesa, Punakha, BHUTAN. 5Department of Veterinary Science, School of Health and Life Sciences, Universitas Airlangga, Surabaya, INDONESIA. Abstract:Tendon injury is a medical indication that requires surgical therapy and prolonged recovery. Collagen plays a crucial role in the wound healing process. Collagen maintains homeostasis, interacts with platelets, and enhances cellular components. Most living organisms consist of collagen components as fibrillar proteins. In this study, the potential properties of type-1 collagen from sea cucumber and Tilapia-skin were evaluated depend on proximate analysis, amino acid composition, and moisture-absorption ability. The result showed that Tilapia-skin has a higher protein and fat composition compared to the sea cucumber. In contrast, moisture, ash, and yield composition showed higher for sea cucumber compared to Tilapiaskin. Meanwhile, based on amino acid analysis was revealed that proline, alanine, methionine, isoleucine, leucine, phenylalanine, and lysine were lower on sea cucumber compared to Tilapia-skin. In conclusion, both type-1 collagen material from sea cucumber and Tilapia-skin might be developed as a biomaterial for tendon injury. It is crucial that further studies be carried out to emphasize the potential of biodegradable and bio-replaceable materials using the in vivo model. Keywords:collagen, Key words: Artificial tendon, Marine biodiversity, Sea cucumber, Tilapia-skinView:PDF (306.96 KB) PDF Images Graphical Abstract ‹ Bioactive Compounds from Purslane (Portulaca oleracea L.) and Star Anise (Illicium verum Hook) as SARS-CoV-2 Antiviral Agent via Dual Inhibitor Mechanism: In Silico Approach up Triterpenoids from Agathis robusta Aerial Parts and Their Hepatopotective Activity ›