ArticleViewAbstractPharmacognosy Journal,2023,15,5,777-780.DOI:10.5530/pj.2023.15.151Published:October 2023Type:Original ArticlePhytochemical Profile, Antioxidant and Antibacterial Activity of the Essential Oil of Luma Chequen (Molina) A. Gray from PeruJulio Luis Díaz-Uribe, María Elena Salazar-Salvatierra, Julio Reynaldo Ruiz-Quiroz, Oscar Herrera- Calderon, Eddie Loyola-Gonzales, Freddy Emilio Tataje-Napuri, and José Francisco Kong-Chirinos Julio Luis Díaz-Uribe1, María Elena Salazar-Salvatierra2, Julio Reynaldo Ruiz-Quiroz2, Oscar Herrera-Calderon3,*, Eddie Loyola- Gonzales4, Freddy Emilio Tataje- Napuri5, José Francisco Kong- Chirinos6 1Basic and Applied Chemistry Department, Faculty of Pharmacy and Biochemistry, Universidad Nacional Mayor de San Marcos, Lima 15001, PERU. 2Institute for Research in Biological Chemistry, Microbiology and Biotechnology “Marco Antonio Garrido Malo”, Faculty of Pharmacy and Biochemistry, Universidad Nacional Mayor de San Marcos, Lima 15001, PERU. 3Department of Pharmacology, Bromatology and Toxicology, Faculty of Pharmacy and Biochemistry, Universidad Nacional Mayor de San Marcos, Lima, PERU. 4Department of Pharmaceutical Science, Faculty of Pharmacy and Biochemistry, Universidad Nacional San Luis Gonzaga, Ica 11001, PERU. 5Departamento de Ciencias Comunitarias, Facultad de Odontología, Universidad Nacional San Luis Gonzaga, Ica 11001, PERU. 6Department of Surgical Clinical Sciences, Faculty of Human Medicine, Universidad Nacional San Luis Gonzaga, Ica 11001, PERU. Abstract:Background: Luma chequen belongs to Myrtaceae family and it is known as “arrayan”. In the traditional medicine from Peru, L chequen is used as aromatic plant, anti-inflammatory and hypocholesterolemic. Objective: To determine the phytochemical profile, evaluate the antioxidant and the antibacterial activity of L. chequen essential oil. Material and Methods: In the analysis of the volatile components a Gas Chromatography coupled to Mass Spectrometry (GC-MS) was used to identify the content of terpenes and sesquiterpenes. 2,2-diphenyl-1-picrylhydrazyl (DPPH) was the method used to determine the antioxidant activity and obtain the half inhibitory concentration (IC50). For the antibacterial activity, a colorimetric macrodilution method was carried out to evaluate the effect of the essential oil of L. chequen against Staphylococcus aureus ATCC 25923 and Escherichia coli ATCC 25922. Results: The analysis by GC-MS showed two major components alpha-pinene (62.89%) followed by 1,8-cineole (11.94%), and propanoic acid, 2-methyl-, 2-methylpropyl ester with 8.67%. In the antioxidant activity against DPPH radical, the essential oil of L. chequen showed an IC50 equivalent to124.60 ± 2.0 μg/mL. In the antibacterial activity, L. chequen had an MIC (minimum inhibitory concentration) for Staphylococcus aureus ATCC 25923 and Escherichia coli ATCC 25922 of 4.35 ± 0 μg/mL and 8.71 ± 0 μg/mL respectively. Conclusion: L. chequen presented monoterpene compounds as main phytoconstituents as well as antioxidant and antibacterial activity in vitro. The essential oil might be used as antimicrobial agent in the future overall against S. aureus. Keywords:Antibacterial., Antioxidant, Aromatic plant, Essential oil, Luma chequeen, Medicinal plantView:PDF (1.08 MB) PDF Images L. chequen plant located at La mar, Ayacucho, Peru ‹ Anti-Neoplastic and Cytotoxicity Potency Measuring of Five Medicago sativa L. (Alfalfa) Leaf Extracts Towards Melanoma (UACC62), Breast (MCF7), Prostate (PC3), and Colon (HCT116) Cancer Cells up Male and Female Rosy Barb Fish (Pethia conchonius) Predation Time Against Aedes aegypti Mosquito Larva and Pupa Stage in the Morning ›