ArticleViewAbstractPharmacognosy Journal,2021,13,4,933-941.DOI:10.5530/pj.2021.13.120Published:July 2021Type:Research ArticlePhytochemical Analysis and Antioxidant Activity of Cotinus coggygria Scop. from Armenian FloraNK Shaboyan, AV Moghrovyan, KH Dumanyan, NH Ghukasyan, AA Altunyan, NI Arshakyan, AM Ghazaryan, GR Ulikhanyan, AL Ginosyan, AS Dadayan, and NB Chichoyan N.K. Shaboyan1, A.V. Moghrovyan2, K.H. Dumanyan2, N.H. Ghukasyan2, A.A. Altunyan2, N.I. Arshakyan2, A.M. Ghazaryan2, G.R. Ulikhanyan2, A.L. Ginosyan3, A.S. Dadayan4, N.B. Chichoyan2,* 1Institute of Pharmacy YSU, 0025,1 Alek Manukyan st, Yerevan, RA, ARMENIA. 2Yerevan State Medical University after M.Heratsi, Department of Pharmacognosy, 0025, 2 Koryun st., Yerevan, RA, ARMENIA. 3Analytical laboratory after Academician Emil Gabrielyan", branch of "Scientific center of drug and medical technology expertise" CJSC, 0051, Komitas Ave., 49/4, Yerevan, RA, ARMENIA. 4Scientific and Production Center «Armbiotechnology» of National Academy of Sciences RA, 0056, 14 Gyurjyan Str., Yerevan, RA, ARMENIA. Abstract:Armenian flora is stood out by the variety of its medicinal and edible plants. Here small plants as well as trees and shrubs are met. Cotinus coggygria of Armenian flora is used in folk medicine. The aim of this investigation was to determine the chemical composition of Armenian flora’s smoke trees leaves’ essential oil and antiradical activity of ethanol extract of leaves and branches of smoke tree. Methods: The aerial parts were extracted by hydrodistillation method, and the composition was analyzed by gas chromatograph interfaced to a mass spectrometer. Antiradical activity of essential oil from leaves and branches was determined by using appropriate methods. Results: The total amount of flavonoids has been determined in the leaves of the smoke tree by miricetin. This analysis revealed that the flavonoid amount in ethanol extract of C. coggygria, growing in Armenia, was 0,94%. In volatile oil of Smoke tree leaves 22 compounds were determined. The results demonstrated that in the essential oil of leaves of Cotinus from Armenian flora predominated Germacrene D, Linalool, formate, ά –Terpineol sesquiterpenes and diterpene alcohol Thunbergol. Ethanol extracts of leaves and branches of Smoke tree showed antioxidant activity. Conclusion: From the results, it is evident that C. coggygria from Armenia flora contains various bioactive compounds and the extracts of leaves pronounced higher antioxidant activity and recommended as a plant of phytopharmaceutical importance. Keywords:Antiradical activity, Cotinus coggygria Scop., DPPH, Essential oil, Ethanol ExtractView:PDF (775.25 KB) PDF Images Graphical Abstract ‹ Hypoglycemic and Antianemia Effects of Chlorophyll from Sauropus androgynus (L) Merr Leaves in Rats up Comparison of Colchicine Content in Gloriosa superba L., Root after Pretreatment by Thai Traditional Medicine Methods ›